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PLGA

" in MedChemExpress (MCE) Product Catalog:

75

Inhibitors & Agonists

2

Fluorescent Dye

49

Biochemical Assay Reagents

5

Peptides

15

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2247
    PLGA (50:50)
    Maximum Cited Publications
    29 Publications Verification

    poly(lactic-co-glycolic acid) (50:50)

    Biochemical Assay Reagents Others
    PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.
    PLGA (50:50)
  • HY-B2247A
    PLGA (75:25)
    5+ Cited Publications

    poly(lactic-co-glycolic acid) (75:25)

    Biochemical Assay Reagents Others
    PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
    PLGA (75:25)
  • HY-W723152

    Drug Intermediate Inflammation/Immunology
    Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems .
    Poly(D,L-lactide-co-glycolide)
  • HY-W127512
    5β-Cholanic acid
    1 Publications Verification

    Drug Intermediate Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid
  • HY-D0791
    TRITC
    1 Publications Verification

    5(6)-Tetramethylrhodamine isothiocyanate

    Fluorescent Dye Others
    TRITC (5(6)-Tetramethylrhodamine isothiocyanate) is a commonly used fluorescent dye, belonging to the Rhodamine derivative family. It exhibits red fluorescence properties (Ex/Em ≈ 550/580 nm). TRITC can be used for cell labeling and imaging .
    TRITC
  • HY-W440823A

    DSPE-PEG1000-NH2 ammonium

    Liposome Cancer
    DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .
    DSPE-PEG1000-Amine ammonium
  • HY-Y0850O

    PVA (Mw 31000-50000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 87-89% hydrolyzed)

    Environmental Pollutants Biochemical Assay Reagents Cancer
    Polyvinyl alcohol (PVA; Poly (Ethenol)) (Mw 31000-50000, 87-89% hydrolyzed) is a polymer with emulsifying and stabilizing properties, with a degree of hydrolysis of 87-89%. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) mainly acts as a stabilizer in the preparation of nanomedicines; it not only maintains the structural integrity of PEGylated PLGA nanoparticles during double emulsion synthesis, but also facilitates the preparation of chitosan/matrine-PLGA nanoparticle aqueous solutions and lipid-polymer nanoparticles. Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed) can be widely used in research related to fields such as breast cancer .
    Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)
  • HY-P10646

    Biochemical Assay Reagents Neurological Disease
    Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction .
    Muscle homing peptide M12
  • HY-156829I

    Biochemical Assay Reagents Others
    PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (15% solution) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (15% solution) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors .
    PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (15% solution)
  • HY-156829B

    Biochemical Assay Reagents Others
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors. The gelation temperature varies with concentration. The higher the concentration, the lower the gelation temperature. The gelation temperature is between 31-34°C at a concentration of 15-20 wt% .
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1)
  • HY-148775A

    Biochemical Assay Reagents Others
    mPEG-PLGA (21500-26500) is a biodegradable polymer composed of methoxypolyethylene glycol (mPEG) and poly (lactic-co-glycolic acid) (PLGA). mPEG-PLGA (21500-26500) is applicable for drug delivery systems .
    mPEG-PLGA (21500-26500)
  • HY-145396

    Biochemical Assay Reagents Cancer
    PLGA-PEG-NH2 is a material to synthesis nanomicelles. PLGA-PEG-NH2 nanomicelle is an efficient delivery system of Irinotecan for targeted colorectal cancer and hepatocellular carcinoma .
    PLGA12000-PEG2000-NH2
  • HY-158089
    PLGA-COOH (MW 80000) (LA/GA 50:50)
    1 Publications Verification

    Biochemical Assay Reagents Others
    PLGA-COOH (MW 80000) (LA/GA 50:50) is a copolymer composed of lactic acid (LA)-glycolic acid (GA) at a molar ratio of 50:50 and a terminal carboxyl group. PLGA-COOH (MW 80000) (LA/GA 50:50) is used in compound delivery systems due to its biocompatibility and biodegradability .
    PLGA-COOH (MW 80000) (LA/GA 50:50)
  • HY-144012H

    16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium

    Liposome Others
    DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
    DPPE-PEG5000
  • HY-156829J

    Biochemical Assay Reagents Others
    PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (20% solution) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (20% solution) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors .
    PLGA-PEG-PLGA (hydrogel) (LA:GA 3:1) (20% solution)
  • HY-156829A

    Biochemical Assay Reagents Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)
  • HY-168943

    Biochemical Assay Reagents Others
    PLGA nanoparticles, 100 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
    PLGA nanoparticles, 100nm
  • HY-148775B

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) has a molecular weight of 20kDA to 5.0kDA and contains a 40:60 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60)
  • HY-P10427

    CXCR Dengue Virus Neurological Disease Inflammation/Immunology Cancer
    DV1 is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .
    DV1
  • HY-156829

    Biochemical Assay Reagents Cancer
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
    PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1)
  • HY-172174

    Fluorescent Dye Others
    Red Fluorescent PLGA nanoparticles, 100nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
    Red Fluorescent PLGA nanoparticles, 100nm
  • HY-176499
    PLGA38000-PEG10000
    1 Publications Verification

    Biochemical Assay Reagents Others
    PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA38000-PEG10000
  • HY-148776

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) has a molecular weight of 20kDA to 5.0kDA and contains a 50:50 ratio of lactic acid (LA) to glycolic acid (GA) molecules. The molecular ratio of LA to GA determines the rate of matrix degradation and protein re-release .
    PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50)
  • HY-154818

    Ac-BSA

    Biochemical Assay Reagents Others
    Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .
    Bovine Serum Albumin, Acetylated
  • HY-P4125

    HIV Fluorescent Dye Infection
    FITC-LC-TAT (47-57) is a FITC-labeled TAT peptide (HY-P0281) (λex: 493 nm, λem: 522 nm). Derived from the trans-activator of transcription (TAT) of human immunodeficiency virus (HIV-1), TAT enhances the yield of heterologous proteins .
    FITC-LC-TAT (47-57)
  • HY-P10427A

    CXCR Dengue Virus Infection
    DV1 TFA is a CXCR4 inhibitor with anti-proteolytic properties that specifically blocks the binding of SDF-1α to its receptor. DV1 TFA inhibits the migration of breast cancer cells and enables the targeted delivery of avidin-PLGA nanoparticles to CXCR4-expressing cancer cells. DV1 TFA not only effectively suppresses the progression of metastatic breast cancer in mouse models, but also preferentially accumulates in brain tumor tissues rather than normal brain tissues, showing potential for inhibiting intracranial tumor metastasis. As a humoral immune stimulant, DV1 TFA induces the production of specific IgG, neutralizing antibodies and cellular immune responses, thereby providing the host with protection against lethal challenges. DV1 TFA has been applied to studies on CXCR4-expressing cancers, glioblastoma, dengue fever and other related diseases .
    DV1 TFA
  • HY-164077

    Biochemical Assay Reagents Others
    mPEG-PLGA is a mucus-penetrating polymer. mPEG-PLGA is a raw material to prepare nanomedicine .
    mPEG-PLGA
  • HY-156829H

    Biochemical Assay Reagents Others
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (20% solution) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (20% solution) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors. The gelation temperature varies with concentration. The higher the concentration, the lower the gelation temperature. The gelation temperature is between 31-34°C at a concentration of 15-20 wt% .
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (20% solution)
  • HY-158255

    Biochemical Assay Reagents Others
    mPEG-PLGA (2000-80000) (LA/GA 50:50) is a copolymer, which consists of hydrophilic mPEG and biodegradable PLGA (molar ratio is 50:50) with a molecular weight of 2000 (mPEG) + 80000 (PLGA). mPEG-PLGA (2000-80000) (LA/GA 50:50) forms nanoparticles or microparticles, which is stable in aqueous solution at different pH values and elevated temperatures as well as in serum. mPEG-PLGA (2000-80000) (LA/GA 50:50) is utilized as carrier material in drug delivery systems .
    mPEG-PLGA (2000-80000) (LA/GA 50:50)
  • HY-148775

    Biochemical Assay Reagents Others
    PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
    PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25)
  • HY-W409806

    Liposome Inflammation/Immunology
    Cholesterylamine is a cationic lipid. Cholesterylamine can be added to the PLGA to prepare PLGA particle having surface charge. Cholesterylamine can be used for drug delivery. Cholesterylamine can be used for autoimmune diseases and allergy research .
    Cholesterylamine
  • HY-178794

    PGE synthase Inflammation/Immunology
    AGU661 is a Microsomal prostaglandin E2 synthase 1 (mPGES-1) inhibitor with an IC50 of 0.22  nM. AGU661 lowers PGE2 formation in human pro-inflammatory M1 macrophages and activated monocytes without affecting other lipid mediator pathways. AGU661 has unfavorable physicochemical properties with poor metabolic stability and strong plasma protein binding tendencies. AGU661 into PLGA-based NPs significantly enhances its bioactivity. AGU661 can be used for inflammatory disorders research .
    AGU661
  • HY-167006

    PLGA10000-PEG3000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA10000-PEG3000-VS (PLGA10000-PEG3000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA10000-PEG3000-VS
  • HY-158255A

    Biochemical Assay Reagents Others
    mPEG-PLGA (22500-26500) is a biodegradable polymer composed of methyl polyethylene glycol (mPEG) and poly(lactic-co-glycolic acid) (PLGA). mPEG-PLGA (22500-26500) can be used in drug delivery systems .
    mPEG-PLGA (22500-26500)
  • HY-168947

    Fluorescent Dye Others
    Green Fluorescent PLGA nanoparticles, 100nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
    Green Fluorescent PLGA nanoparticles, 100nm
  • HY-D0153

    Fluorescent Dye Cancer
    Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
    Tetramethylrhodamine-5-isothiocyanate
  • HY-167033

    PLGA4000-PEG5000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA4000-PEG5000-VS (PLGA4000-PEG5000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA4000-PEG5000-VS
  • HY-167035

    PLGA5000-PEG2000-Vinylsulfone

    Biochemical Assay Reagents Others
    PLGA5000-PEG2000-VS (PLGA5000-PEG2000-Vinylsulfone) is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .
    PLGA5000-PEG2000-VS
  • HY-168943A

    Biochemical Assay Reagents Others
    PLGA nanoparticles, 500 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
    PLGA nanoparticles, 200nm
  • HY-168943B

    Biochemical Assay Reagents Others
    PLGA nanoparticles, 500 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
    PLGA nanoparticles, 500nm
  • HY-168943C

    Biochemical Assay Reagents Others
    PLGA nanoparticles, 1μm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
    PLGA nanoparticles, 1μm
  • HY-156829E

    Biochemical Assay Reagents Others
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (15% solution) is a biodegradable thermosensitive hydrogel product that can undergo phase transition at a specific temperature. PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (15% solution) can be widely used in drug delivery systems, tissue engineering, wound dressings, and biosensors. The gelation temperature varies with concentration. The higher the concentration, the lower the gelation temperature. The gelation temperature is between 31-34°C at a concentration of 15-20 wt% .
    PLGA-PEG-PLGA (hydrogel) (LA:GA 7:1) (15% solution)
  • HY-172168A

    Fluorescent Dye Others
    Orange Fluorescent PLGA nanoparticles, 200nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
    Orange Fluorescent PLGA nanoparticles, 200nm
  • HY-172168B

    Fluorescent Dye Others
    Orange Fluorescent PLGA nanoparticles, 500nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
    Orange Fluorescent PLGA nanoparticles, 500nm
  • HY-172168

    Fluorescent Dye Others
    Orange Fluorescent PLGA nanoparticles, 100nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
    Orange Fluorescent PLGA nanoparticles, 100nm
  • HY-172174B

    Fluorescent Dye Others
    Red Fluorescent PLGA nanoparticles, 500nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
    Red Fluorescent PLGA nanoparticles, 500nm
  • HY-172174A

    Fluorescent Dye Others
    Red Fluorescent PLGA nanoparticles, 200nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
    Red Fluorescent PLGA nanoparticles, 200nm
  • HY-145396D

    Biochemical Assay Reagents Others
    PLGA20000-PEG10000-NH2 is a biochemical reagent.
    PLGA20000-PEG10000-NH2
  • HY-145396A

    Biochemical Assay Reagents Others
    PLGA20000-PEG1000-NH2 is a biochemical reagent.
    PLGA20000-PEG1000-NH2
  • HY-145396C

    Biochemical Assay Reagents Others
    PLGA20000-PEG5000-NH2 is a biochemical reagent.
    PLGA20000-PEG5000-NH2

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