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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
413 Results for "
RNA synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (413)
413 Results for "RNA synthesis" in MCE Product Catalog:
226
226 Publications Verification
Synonyms: GS-5734
Target:
Research Areas:
Remdesivir (GS-5734) is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection .
79
79 Cited Publications
Synonyms: 7-Ethyl-10-hydroxycamptothecin
71
71 Cited Publications
Target:
Research Areas:
CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively .
49
49 Cited Publications
Synonyms: Agrept; Agrimycin; Streptomycin A
Category:
43
43 Cited Publications
Synonyms: Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride
43
43 Cited Publications
Cat. No.: HY-13062A
CAS No.: 20830-81-3
Synonyms: Daunomycin; RP 13057; Rubidomycin
38
Research Areas:
Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase . Epirubicin inhibits DNA and RNA synthesis. Epirubicin is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity .
38
38 Cited Publications
Synonyms: 4'-Epidoxorubicin hydrochloride
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase . Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity .
24
Category:
Disease Research Antibacterial Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields
Target:
24
Target:
Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
24
Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Disease Research Antibacterial Anticancer Disease Research Fields
Target:
24
24
24 Cited Publications
Synonyms: 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride
24
24 Cited Publications
Synonyms: 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
24
24 Cited Publications
Cat. No.: HY-W015213
CAS No.: 6055-72-7
20
20 Cited Publications
Synonyms: TR 700; Torezolid; DA-7157
Target:
Research Areas:
Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.
19
Idarubicin is an orally active and potent anthracycline antileukemic agent. Idarubicin inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin shows induction of DNA damage. Idarubicin inhibits DNA synthesis and of c-myc expression. Idarubicin inhibits the growth of bacteria and yeasts .
16
Target:
Research Areas:
L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis .
15
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
13
13 Cited Publications
Research Areas:
CR-1-31-B is a synthetic rocaglate and a potent eIF4A inhibitor. CR-1-31-B exhibits powerful inhibitory effects over eIF4A by perturbing the interaction between eIF4A and RNA, sequentially impeding initiation during protein synthesis. CR-1-31-B perturbs association of Plasmodium falciparum eIF4A (PfeIF4A) with RNA. CR-1-31-B induces apoptosis of neuroblastoma and gallbladder cancer cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
