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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Skin pigmentation
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Skin pigmentation" in MCE Product Catalog:
2
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Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes. Tyrosinase can be used in research on Parkinson's disease, melanoma and pigmentation .
Synonyms: MT-7117
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Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation .
Cat. No.: HY-P10533
CAS No.: 845727-64-2
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Cat. No.: HY-W250145
CAS No.: 8005-03-6
Synonyms: Nigrosine
Cat. No.: HY-P5269
CAS No.: 887140-79-6
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Cat. No.: HY-109114A
CAS No.: 2490660-87-0
Synonyms: MT-7117 phosphate
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Dersimelagon phosphate is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon phosphate shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon phosphate can be used for the research of skin pigmentation .
Cat. No.: HY-173512
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mTYR-IN-1 (compound 3e) is a reversible and competitive mTYR inhibitor with an IC50 of 4.86 μM. mTYR-IN-1 can be used in the study of skin pigmentation .
Synonyms: trans-10-Pentadecenoic acid
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10 (E)-Pentadecenoic acid (trans-10-Pentadecenoic acid) is a melanin synthesis inhibitor. 10 (E)-Pentadecenoic acid inhibits nuclear translocation and reduces the protein level of phosphorylated microphthalmia-associated transcription factor (MITF), as well as decreases intracellular tyrosinase activity. 10 (E)-Pentadecenoic acid can be used in the research of skin pigmentation disorders .
Cat. No.: HY-W267446
CAS No.: 6295-35-8
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Citrus × aurantium Linnaeus Rutaceae Coumarins Phenylpropanoids Plants Daphniphyllum macropodum Miq.
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Cat. No.: HY-179100
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Tyrosinase-IN-45 (compound 4) is a tyrosinase inhibitor (IC50 = 1.51 μM). Tyrosinase-IN-45 can reduce the melanin content. Tyrosinase-IN-45 can be used for skin whitening and improving pigmentation .
Cat. No.: HY-N10337
CAS No.: 74119-87-2
Synonyms: (-)-Norjuziphine
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Cat. No.: HY-N9846
CAS No.: 62346-14-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
