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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
107 Results for "
Trimethylamine hydrochloric acid-15N
" in MedChemExpress (MCE) Product Catalog:
Products (107)
107 Results for "Trimethylamine hydrochloric acid-15N" in MCE Product Catalog:
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43 Publications Verification
Cat. No.: HY-P0014
CAS No.: 204656-20-2
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Neurological Disease Metabolic Disease Inflammation/Immunology
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43 Publications Verification
Cat. No.: HY-P0014B
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12 Cited Publications
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3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3 Cited Publications
Cat. No.: HY-P3462A
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Irsogladine (Dicloguamine) is an orally active gastric mucosal protective agent. Irsogladine inhibits breast cancer recurrence and lung metastasis in nude mice . Irsogladine inhibits the transcriptional activities of NF-κB and AP-1, suppresses the activities of PDE and PDE4 to elevate intracellular cAMP levels, and activates TRPV1 and KATP channels. Irsogladine enhances iNOS expression, NO production, and the activation of cAMP-responsive elements. Irsogladine inhibits the development and progression of intestinal polyps in Apc-mutant mice. Irsogladine alleviates oxidative stress, increases gastric mucosal blood flow, and stimulates the production of endogenous prostaglandins. Irsogladine promotes insulin secretion in MIN6 cells. Irsogladine inhibits tumor angiogenesis, cancer cell proliferation, and the production of proinflammatory cytokines. Irsogladine exerts protective effects on astrocytes in ethanol/hydrochloric acid-induced gastric ulcers in mice. Irsogladine prevents colitis in IL-10 gene-deficient mice by reducing the production of IL-12 and IL-23. Irsogladine upregulates gap junction intercellular communication in pancreatic cancer cells via the PKA pathway. Irsogladine is applicable to research related to breast cancer, intestinal polyposis, gastric ulcer, spontaneous colitis, glioma, liver cancer, and pancreatic cancer [5][6] .
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2 Cited Publications
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Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
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1 Cited Publications
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1 Cited Publications
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Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
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1 Cited Publications
Cat. No.: HY-P1108A
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1 Cited Publications
Cat. No.: HY-P10218
CAS No.: 479482-23-0
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1 Cited Publications
Cat. No.: HY-P10218A
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
