Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
aldehyde intermediate
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "aldehyde intermediate" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: Triose phosphate
Cat. No.: HY-W039943
CAS No.: 121584-52-9
Target:
Research Areas:
Acetyl-cyclosporin A aldehyde is an acetylated derivative of Cyclosporin A (HY-B0579) with a reducible aldehyde group. Acetyl-cyclosporin A aldehyde serves as a synthetic intermediate for the calcineurin inhibitor Voclosporin (HY-106638). Acetyl-cyclosporin A aldehyde can act as a substrate for ruthenium nanocatalyzed reductive deuteration reactions, producing the corresponding deuterated alcohol with selective deuterium incorporation at the α-position of the oxygen atom .
Cat. No.: HY-69052
CAS No.: 25016-11-9
Cat. No.: HY-W004301
CAS No.: 112-54-9
Cat. No.: HY-W142618
CAS No.: 13265-84-4
Cat. No.: HY-W127521
CAS No.: 5910-87-2
Target:
Cat. No.: HY-W127515
CAS No.: 557-48-2
Synonyms: Violet leaf aldehyde
Cat. No.: HY-W047688
CAS No.: 216961-61-4
Synonyms: 1-Boc-1,10-diaminodecane
Target:
Research Areas:
tert-Butyl (10-aminodecyl) carbamate (1-Boc-1,10-diaminodecane) is a synthetic intermediate that serves as a PROTAC linker in PROTAC synthesis and other conjugation applications. tert-Butyl (10-aminodecyl) carbamate is an alkane chain with a terminal amine and a Boc-protected amino group. The amine group can react with carboxylic acids, active NHS esters, carbonyl groups (ketones, aldehydes), etc. The Boc group can be deprotected under mild acidic conditions to form a free amine .
Cat. No.: HY-W599279
CAS No.: 2761170-84-5
Research Areas:
ABS-752 is an orally active prodrug targeting CRBN-modulating molecular glue with selectivity in protein degradation. ABS-752 preferentially degrades GSPT1 and induces cytotoxicity through this degradation, while it also degrades NEK7, SALL4 and CK1α, with weaker degradation potency against CK1α. As a prodrug, ABS-752 requires metabolic activation to ABT-002 to form the active complex; VAP-1 mediates its conversion to an aldehyde intermediate. ABS-752 induces cell death, reduces cell viability, and exhibits antitumor activity, leading to regression and inhibition of tumor growth. ABS-752 shows no cytotoxicity in primary human hepatocytes. ABS-752 can be used in the research of hepatocellular carcinoma .
Cat. No.: HY-32786
CAS No.: 149806-06-4
Cat. No.: HY-44114
CAS No.: 82689-15-4
Synonyms: tert-Butyl(S)-(1-(4-(benzyloxy)phenyl)-3-oxopropan-2-yl)carbamate
Target:
Research Areas:
Boc-tyr(bzl)-aldehyde (tert-Butyl(S)-(1-(4-(benzyloxy)phenyl)-3-oxopropan-2-yl)carbamate) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W015012
CAS No.: 90421-78-6
Target:
Research Areas:
NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
Cat. No.: HY-Y1747
CAS No.: 537013-51-7
Cat. No.: HY-169496
CAS No.: 64091-14-1
Target:
Research Areas:
TBS-Corey lactone aldehyde is a versatile, hydroxyl-protected intermediate for the synthesis of prostaglandins and prostaglandin analogs.
Cat. No.: HY-W653739
CAS No.: 41944-86-9
Synonyms: Abscisic aldehyde
Target:
Research Areas:
(+)-Abscisic Aldehyde (ABAld) is an intermediate in the biosynthesis of the plant hormone abscisic acid (ABA). (+)-Abscisic Aldehyde is produced by the dehydrogenation of xanthoxin by xanthoxin dehydrogenases, followed by selective oxidation by abscisic aldehyde oxygenase. (+)-Abscisic Aldehyde has an oxidizing PsAOγ activity and it correlates with ABA accumulation in the old leaves of pea plants with long exposure of salinity, ammonium or nitrogen deficiency. (+)-Abscisic Aldehyde can be used for plant growth and development research .
Cat. No.: HY-W127505S
Cat. No.: HY-W800617
CAS No.: 2055024-63-8
Target:
Research Areas:
NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
Cat. No.: HY-W127515S
CAS No.: 1083053-38-6
Synonyms: Violet leaf aldehyde-13C2
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
