69 Results for "

amyloid beta-protein

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "amyloid beta-protein" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-N0931
CAS No.: 1477949-42-0
Synonyms: CAY-10683
Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-β protein fragment 25–35. STA can be used for cancer and neurological disease research .
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6
6 Cited Publications
Cat. No.: HY-19369
CAS No.: 292632-98-5
Synonyms: L-685,458
Target:  

γ-secretase Apoptosis

Research Areas:  

Neurological Disease Cancer

L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimer’s disease (AD) and cancers .
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1
1 Cited Publications
Cat. No.: HY-P3908
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .
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Cat. No.: HY-P5096
CAS No.: 1802087-77-9
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

FITC-β-Ala-Amyloid β-Protein (1-42) is a FITC tagged Aβ1-42 peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .
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Cat. No.: HY-P1466
CAS No.: 131580-10-4
Synonyms: amyloid β-protein (1-16)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-16) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-124322
CAS No.: 1262857-73-7
Purity:  99.08%
NB-360 is a potent, brain penetrable and orally active β‐secretase 1/2 (BACE1/BACE2) dual inhibitor with IC50 values of 5 and 6 nM. NB-360 can inhibit amyloid-β protein accumulation. NB-360 can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease .
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Cat. No.: HY-D1443
CAS No.: 291766-06-8
Synonyms: (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
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Cat. No.: HY-P4882A
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) TFA is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) TFA is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
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Cat. No.: HY-P10040
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Gln22)β-Amyloid (1-40) human is an amyloid beta protein (Aβ)-containing peptide used in Alzheimer's disease research .
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Cat. No.: HY-P1046
CAS No.: 183745-81-5
Synonyms: amyloid β-protein (1-15)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-N13742
CAS No.: 219565-74-9
Synonyms: Dihydrohonokiol
Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
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Cat. No.: HY-P1468
CAS No.: 109770-29-8
Synonyms: amyloid β-protein (1-28)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-159083
CAS No.: 937012-09-4
Purity:  99.01%
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

DN5355 is a small molecule compound that targets amyloid β protein (Aβ) and hyperphosphorylated tau protein. DN5355 can inhibit the aggregation of Aβ and tau protein and disaggregate the formed Aβ and tau protein fibers. DN5355 can be used in the study of Alzheimer's disease .
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Cat. No.: HY-P4882
CAS No.: 183449-57-2
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated pyroglutamylated β-amyloid peptide. (Pyr3)-Amyloid β-Protein (3-42) forms stable β-sheet structures across different pH values, co-oligomerizes with Aβ1-42 to form cytotoxic oligomers, induces tau-dependent cytotoxicity and neuronal loss, inhibits hippocampal LTP, and exhibits stronger protease resistance. (Pyr3)-Amyloid β-Protein (3-42) exists in the brain tissues of human Alzheimer's disease patients, correlates with the pathogenesis of Alzheimer's disease, and follows a unique, faster oligomerization pathway. (Pyr3)-Amyloid β-Protein (3-42) can be used in Alzheimer's disease-related research .
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Cat. No.: HY-P4788
CAS No.: 903883-22-7
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Acetyl-Amyloid β-Protein (1-6) amide is a hexapeptide that contains a potential copper(II) binding site. Acetyl-Amyloid β-Protein (1-6) amide can be used for research of Alzheimer's disease and related disorders .
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Cat. No.: HY-P3780
CAS No.: 1802078-25-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42) is the 36-42 fragment of Amyloid β-Protein. β-amyloid, a polypeptide made up of 36-43 amino acids, is the main component of amyloid plaques found in the brains of people with Alzheimer's disease. β-amyloid oligomers (Aβos) plays A key role in the progression of Alzheimer's disease (AD) by inducing neuronal damage and cognitive impairment .
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Cat. No.: HY-P4886A
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Amyloid β-Protein (3-42) TFA is a precursor of Pyr peptide. Pyroglutamic acid-modified Aβ (pEAβ) (3-42) is the core of the amyloid plaque in Alzheimer's disease. pEAβ (3-42) accelerates the aggregation of Aβ(1-42), while Aβ(1-42) significantly slows down the primary and secondary nucleation of pEAβ(3-42).
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Cat. No.: HY-P3846
CAS No.: 1802086-22-1
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Glu20)-Amyloid β-Protein (1-42) is a slower fibrillizing variant of amyloid β-protein (Aβ). The Glu20 mutation reduces the aggregation propensity of Aβ42 and prevents accumulation of the slowly fibrillizing peptide. Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease .
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Cat. No.: HY-P3859
CAS No.: 1802086-21-0
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) can be used in research of Alzheimer's disease .
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Cat. No.: HY-P4884
CAS No.: 285554-31-6
Target:  

Amyloid-β

Research Areas:  

Others

Amyloid β-Protein (1-46) is aAβ Fragment.
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