147 Results for "

artificial

" in MedChemExpress (MCE) Product Catalog:
Products (147)

147 Results for "artificial" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-113424A
CAS No.: 4235-95-4
Purity:  98.11%
Synonyms: DOPC
1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes.
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5
5 Cited Publications
Cat. No.: HY-N0119
CAS No.: 18916-17-1
Synonyms: Naringin DC
Naringin Dihydrochalcone is an artificial sweetener derived from naringin. Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin suppresses NF-κB signaling pathway.
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4
4 Cited Publications
Cat. No.: HY-N0154
CAS No.: 20702-77-6
Synonyms: Neohesperidin DC; NHDC
Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.
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3
3 Cited Publications
Cat. No.: HY-N0614
CAS No.: 56038-13-2
Synonyms: E955; Trichlorosucrose
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents .
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3
3 Cited Publications
Cat. No.: HY-141571
CAS No.: 67254-28-8
Purity:  98.70%
Synonyms: Dioleoylphosphatidylglycerol sodium
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .
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2
2 Cited Publications
Cat. No.: HY-111915
CAS No.: 108392-02-5
Purity:  99.44%
Synonyms: 18:1 PA sodium salt
1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA sodium salt) is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes .
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1
1 Cited Publications
Cat. No.: HY-113437A
CAS No.: 169051-60-9
Purity:  ≥98.0%
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite . It is used in the generation of micelles, liposomes, and artificial membranes.
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1
1 Cited Publications
Cat. No.: HY-12242
CAS No.: 67469-81-2
Purity:  99.45%
Target:  

Dopamine Transporter

Research Areas:  

Neurological Disease

GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice .
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1
1 Cited Publications
Cat. No.: HY-139338
CAS No.: 13101-54-7
Purity:  ≥99.0%
Erlose is a trisaccharide sucrose derivative and low-calorie sweetener synthesized from glucose and sucrose via an α-glucosidase-mediated transglycosylation reaction. Erlose is often used as a marker to identify whether honey is adulterated with artificial sucrose. Erlose has approximately half the sweetness of sucrose but a similar taste, and it effectively inhibits crystal formation and browning reactions during food heat treatment .
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1
1 Cited Publications
Cat. No.: HY-W011183
CAS No.: 3459-18-5
4-Nitrophenyl-N-acetyl-β-D-glucosaminide, an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), can be used in rapid and accurate rate assay for N-acetyl-beta-D-hexosaminidase. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide is highly soluble and stable. 4-Nitrophenyl-N-acetyl-β-D-glucosaminide can be used for the study of renal tubular injury .
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1
1 Cited Publications
Cat. No.: HY-N2045
CAS No.: 81-14-1
Musk ketone is a widely used artificial fragrance. Musk ketone is also a cytochrome P450 enzyme inducer. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis .
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1
1 Cited Publications
Cat. No.: HY-127032
CAS No.: 75345-27-6
Purity:  ≥99.0%
Synonyms: Polidronium chloride
Research Areas:  

Infection

Polyquaternium-1 (Polidronium chloride; PQ-1) is an antimicrobial preservative and an activator of NF-κB. Polyquaternium-1 targets bacterial cell membranes, commonly used in ophthalmic surgery. Polyquaternium-1 adsorbs to the surface of microbial membranes through its polycationic properties, destroying membrane integrity and inducing potassium ion leakage, leading to bacterial death. Polyquaternium-1 exerts antimicrobial effects at a concentration of 0.001% and has low toxicity to mammalian cells. Polyquaternium-1 can be used to prepare products such as glaucoma eye drops (Travoprost preparations containing PQ-1), artificial tears, and contact lens solutions to reduce the ocular surface toxicity of traditional preservatives such as benzalkonium chloride (HY-B2232) .
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1
1 Cited Publications
Cat. No.: HY-P99014
CAS No.: 1864871-20-4
Synonyms: ARGX-110

Research Areas:  

Inflammation/Immunology Cancer

Cusatuzumab (ARGX-110) is a selective competitive blocker targeting CD70 (with an equilibrium dissociation constant of 17 pM for binding to human CD70). Cusatuzumab also possesses enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity. It is a humanized IgG1 monoclonal antibody, artificially synthesized through humanization and genetic engineering modifications (CH2 region mutation to enhance effector function). Cusatuzumab has a dual mechanism of action: firstly, it competitively blocks the interaction between CD70 and CD27, inhibiting the CD27-NF-κB signaling pathway, reducing regulatory T cell (Treg) activation and tumor cell proliferation; secondly, by enhancing binding to FcγRIIIa, it mediates ADCC and antibody-dependent cellular phagocytosis (ADCP), directly lysing CD70-positive tumor cells. Cusatuzumab can efficiently eliminate leukemia stem cells (LSCs), induce tumor cell differentiation and apoptosis, restore immune surveillance, and target CD70-positive tumors. Cusatuzumab is used in the study of acute myeloid leukemia (AML) .
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Cat. No.: HY-Y0272
CAS No.: 81-07-2
Category:  

Microorganisms

Target:  

Bacterial

Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties .
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Cat. No.: HY-W011053
CAS No.: 165450-17-9
Research Areas:  

Metabolic Disease

Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
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Cat. No.: HY-D0259
CAS No.: 16423-68-0
Synonyms: Erythrosin extra bluish
Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
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Cat. No.: HY-D0195
CAS No.: 55589-62-3
Acesulfame potassium is a synthetic sweetener. Long-term use of Acesulfame potassium can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame potassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion .
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Cat. No.: HY-D1378
CAS No.: 959839-06-6
C-Laurdan is a modified Laurdan (HY-D0080) probe that imaging lipid rafts with environmentally sensitive fluorescence. C-Laurdan can be used in research of lipid arrangement and fluidity in biological membranes or artificial lipid membranes .
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Cat. No.: HY-W017522
CAS No.: 124-04-9
Synonyms: Hexanedioic acid
Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc .
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Cat. No.: HY-125940
CAS No.: 200880-41-7
Purity:  ≥98.0%
Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium
DPPG (UV radiation exposure) suffers cleavage of C―O, C=O and -PO2- bonds and loses monolayer stability; when DNA exists in the subphase, ionic degradation products from DPPG and DNA stabilize intact DPPG molecules and mitigate UV irradiation damage .
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