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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
cell wall structures
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "cell wall structures" in MCE Product Catalog:
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3 Cited Publications
Cat. No.: HY-B0848
CAS No.: 41814-78-2
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Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .
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Alkaloids Human Gut Microbiota Metabolites Neurological Disease Other Alkaloids Endogenous metabolite Disease Research Fields Cancer
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1 Cited Publications
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1 Cited Publications
Cat. No.: HY-159688
CAS No.: 104145-95-1
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Cefditoren is a broad-spectrum oral active cephalosporin that acts as a penicillin-binding protein (PBP) inhibitor. Cefditoren binds to specific PBPs in Gram-positive and Gram-negative bacteria, thereby inhibiting cell wall synthesis. Cefditoren also reduces serum levels of the inflammatory biomarkers IL-6 and KL-6. Cefditoren can be used in research related to acute exacerbation of chronic bronchitis, pharyngitis-tonsillitis, uncomplicated skin and skin structure infections, respiratory tract infections, acute pyelonephritis, and enterococcal endocarditis .
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Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) .
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Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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Cat. No.: HY-N7101
CAS No.: 87239-81-4
Synonyms: U-76,252; CS-807
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Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
Cat. No.: HY-W744966
CAS No.: 374726-62-2
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Mandipropamid is a cellulose synthase (CesA3) inhibitor and fungicide, with an IC50 of 19.8 nM against Phytophthora infestans. Mandipropamid inhibits the synthesis of crystalline cellulose on the cell surface, disrupts the cell wall structure of oomycetes, and induces germ tube tip swelling and growth arrest in Phytophthora infestans. S-Mandipropamid, an isomer of Mandipropamid, exhibits enantioselective acute toxicity to zebrafish embryos and larvae. Mandipropamid is applicable to studies related to plant infections .
Cat. No.: HY-W141916
CAS No.: 7093-67-6
Synonyms: Tetraglycylglycine; Gly-Gly-Gly-Gly-Gly; NSC 96353
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A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). A40926 irreversibly inhibits cell wall synthesis by competitively binding to this target, and has high bactericidal activity against Gram-positive bacteria (such as Staphylococcus, Streptococcus) and Neisseria gonorrhoeae, with MIC=0.06-2 μg/mL, and is also effective against penicillin-resistant strains. A40926 blocks peptidoglycan cross-linking, destroys cell wall integrity, and causes bacterial lysis and death. A40926 has a fat-soluble fatty acid structure, which can increase serum concentrations and prolong the duration of action (e.g., the terminal half-life in rats is 61.22 h) .
Cat. No.: HY-Y0395
CAS No.: 25487-66-5
Cat. No.: HY-147097
CAS No.: 87156-00-1
EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W286362
CAS No.: 6832-98-0
Synonyms: Palmitic acid anilide
Palmitanilide (Palmitic acid anilide) is an antibacterial agent against Gram-positive bacteria. Palmitanilide can electrostatically bind to relevant components in the cell walls of Gram-positive bacteria (such as Bacillus cereus), alter the cell membrane structure, and affect the normal functions of the cells. Palmitanilide is promising for research of infectious diseases caused by Gram-positive bacteria .
Cat. No.: HY-N15356
CAS No.: 2489590-40-9
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Cat. No.: HY-W744966R
CAS No.: 374726-62-2
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Mandipropamid (Standard) is the analytical standard of Mandipropamid (HY-W744966). This product is intended for research and analytical applications. Mandipropamid is a cellulose synthase (CesA3) inhibitor and fungicide, with an IC50 of 19.8 nM against Phytophthora infestans. Mandipropamid inhibits the synthesis of crystalline cellulose on the cell surface, disrupts the cell wall structure of oomycetes, and induces germ tube tip swelling and growth arrest in Phytophthora infestans. S-Mandipropamid, an isomer of Mandipropamid, exhibits enantioselective acute toxicity to zebrafish embryos and larvae. Mandipropamid is applicable to studies related to plant infections .
Cat. No.: HY-113100R
CAS No.: 18233-70-0
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Cat. No.: HY-N7101R
CAS No.: 87239-81-4
Synonyms: U-76,252 (Standard); CS-807 (Standard)
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Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
Cat. No.: HY-N7101S
Synonyms: U-76-d7,252-d7; CS-807-d7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
