Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10197 Results for "
chemically
" in MedChemExpress (MCE) Product Catalog:
Products (10197)
10197 Results for "chemically" in MCE Product Catalog:
364
315
Domaines de recherche:
(+)-JQ-1 (JQ1), a chemical probe, is a potent, specific, CNS-penetrant and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)) . (+)-JQ-1 also activates autophagy .
120
120 Cited Publications
Domaines de recherche:
A-485, a chemical probe, is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively .
84
Target:
Domaines de recherche:
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
84
Target:
Domaines de recherche:
Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
50
50 Cited Publications
Cat. No.: HY-D1374
CAS No.: 1144107-82-3
46
46 Cited Publications
Cat. No.: HY-K0030
MCE Deacetylase Inhibitor Cocktail is a synergistic combination of chemicals designed to preserve the acetylation state of proteins.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
33
33 Cited Publications
Target:
Domaines de recherche:
GSK343, a chemical probe, is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM.
28
28 Cited Publications
Target:
Domaines de recherche:
UNC0642, a chemical probe, is a potent and selective lysine methyltransferases G9a and GLP inhibitor, with an IC50 of <2.5 nM for G9a.
26
26 Cited Publications
Cat. No.: HY-19725
CAS No.: 1235034-55-5
Target:
Domaines de recherche:
A-1155463, a chemical probe, is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. A-1155463 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
25
25
25 Cited Publications
Synonyms: 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride
25
25 Cited Publications
Synonyms: 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
25
25 Cited Publications
Cat. No.: HY-W015213
CAS No.: 6055-72-7
24
24 Cited Publications
Cat. No.: HY-19615
CAS No.: 1831110-54-3
Target:
Domaines de recherche:
MS023, a chemical probe, is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively .
22
22 Cited Publications
Target:
Domaines de recherche:
IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases .
20
20 Cited Publications
Target:
Domaines de recherche:
BAY-1816032, a chemical probe, is a potent and oral available BUB1 (budding uninhibited by benzimidazoles 1) kinase inhibitor with an IC50 of 7 nM.
18
17
17 Cited Publications
Target:
Domaines de recherche:
UNC1999, a chemical probe, is a SAM-competitive, potent and selective inhibitor of EZH2/1 with IC50s of <10 nM and 45 nM, repectively.
17
17 Cited Publications
Target:
Domaines de recherche:
MLi-2, a chemical probe, is an orally active and highly selective LRRK2 inhibitor with an IC50 of 0.76 nM. MLi-2 has the potential for Parkinson’s disease .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
