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Results for "

delivery system

" in MedChemExpress (MCE) Product Catalog:

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Targets Recommended: Complement System

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109506

DPPC 5+ Cited Publications 129Y83	Liposome Endogenous Metabolite	Others
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-N7131

Coumarin 6 20+ Cited Publications	Fluorescent Dye	Others
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-160523

DBCO Ir catayst	Biochemical Assay Reagents	Others
DBCO Ir catalyst is an iridium catalyst labeled with DBCO. DBCO Ir catalyst can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems .

HY-126437E

Poly-L-lysine hydrobromide (MW 15000-30000)	Biochemical Assay Reagents	Others
Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) is an amino acid polymer with positive charge, and it serves as a non-specific attachment factor for cells. Poly-L-lysine hydrobromide (with a molecular weight of 15,000 - 30,000) can be used for gene delivery and the construction of nano-delivery systems .

HY-B1620D

Polyvinylpyrrolidone K25 PVP K25; Polyvidone K25; Povidone K25	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K25 is a preferable binder for granules and tablets .

HY-P10128

GE11 1 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .

HY-144007

Chol-PEG	Liposome	Others
Chol-PEG is a nonionic surfactant vesicles and can be used for a blood-persistent drug delivery system .

HY-Y0873O

PEG35000 Polyethylene glycol 35000	Environmental Pollutants Biochemical Assay Reagents	Others
PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems .

HY-46759

Genevant CL1	Liposome	Infection
Genevant CL1 is an ionizable lipid (pKa = 6.3) suitable for the preparation of lipid nanoparticles (LNPs) for delivering nucleic acid payloads and intramuscular vaccines. Genevant CL1 is a component of lipid nanoparticle delivery systems for mRNA vaccines .

HY-W763806

Zein	Environmental Pollutants Biochemical Assay Reagents	Others
Zein is a plant protein‐based polymer, can be used to prepare nanofibrous mats through electrospun. Zein has good cell compatibility and easy fabrication ability, and can be used in drug delivery systems .

HY-121447

Heneicosanoic acid	Endogenous Metabolite	Metabolic Disease
Heneicosanoic acid is an odd-chain saturated fatty acid widely present in human milk, fish, seeds, and cerebrosides in the cell membranes of the nervous system. Heneicosanoic acid can form Langmuir monolayers and is often used as a model to study lipid self-assembly and disassembly processes in biological membranes and drug delivery systems. In the low-temperature L'2 and CS crystalline phases, Heneicosanoic acid undergoes local oscillations, which in turn drive the spontaneous formation and expulsion of micelles and vesicles .

HY-143702

Fluorescent DOTAP NBD-DOTAP	Fluorescent Dye Liposome	Inflammation/Immunology Cancer
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .

HY-174264

DMG-PEG2000-NHS	Biochemical Assay Reagents	Others
DMG-PEG2000-NHS is a polyethylene glycol lipid with a molecular weight of 2000, which can be used to construct novel drug delivery systems that confer mucoadhesive and cell-targeting capabilities to lipid nanoparticles .

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-148775A

mPEG-PLGA (21500-26500)	Biochemical Assay Reagents	Others
mPEG-PLGA (21500-26500) is a biodegradable polymer composed of methoxypolyethylene glycol (mPEG) and poly (lactic-co-glycolic acid) (PLGA). mPEG-PLGA (21500-26500) is applicable for drug delivery systems .

HY-145396

PLGA12000-PEG2000-NH2	Biochemical Assay Reagents	Cancer
PLGA-PEG-NH2 is a material to synthesis nanomicelles. PLGA-PEG-NH2 nanomicelle is an efficient delivery system of Irinotecan for targeted colorectal cancer and hepatocellular carcinoma .

HY-W002879

4-Hydroxyphenylboronic acid pinacol ester	Reactive Oxygen Species (ROS)	Inflammation/Immunology
4-Hydroxyphenylboronic acid pinacol ester is a ROS-responsive component. 4-Hydroxyphenylboronic acid pinacol ester can structurally modify hyaluronic acid to prepare ROS-responsive intelligent nanocarriers and compound delivery systems. 4-Hydroxyphenylboronic acid pinacol ester endows hyaluronic acid-based nanocarriers with ROS responsiveness, enabling them to rapidly release the encapsulated Curcumin (HY-N0005) in the presence of reactive oxygen species. 4-Hydroxyphenylboronic acid pinacol ester is applicable to research related to periodontitis. 4-Hydroxyphenylboronic acid pinacol ester can also be used for the synthesis of boronic acid-modified resins .

HY-N1446A

Glycerol Monoleate Maximum Cited Publications 60 Publications Verification	Endogenous Metabolite	Others
Glycerol Monoleate is a non-toxic, biodegradable, biocompatible, lipophilic glycerol fatty acid ester. Glycerol Monoleate exhibits hemolytic properties. Glycerol Monoleate is combined with bile salts for use as an emulsifier and absorption enhancer. Glycerol Monoleate can be applied in drug delivery systems and in vitro siRNA delivery .

HY-143692

SQDG	Liposome HSV Topoisomerase MDM-2/p53 Apoptosis	Infection Inflammation/Immunology Cancer
SQDG inhibits topoisomerase I and P-selectin receptor, exhibits anti-inflammatory, antiviral and antitumor activities. SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations .

HY-W133967

Calcium alginate	Environmental Pollutants Biochemical Assay Reagents	Inflammation/Immunology
Calcium alginate is a biopolymer that can be used for developing oral agent-delivery systems . Calcium alginate is a pH sensitive hydrogel stable in acidic media and soluble in basic media .

HY-W109224

3,3'-(Propane-2,2-diylbis(sulfanediyl))dipropionic acid	ADC Linker	Cancer
3,3'-(Propane-2, 2-Diylbis (sulfanediyl))dipropionic acid is a ROS-sensitive cleavable linker that can be used in the synthesis of ADCs. 3,3'-(Propane-2,2-diylbis(sulfanediyl))dipropionic acid is promising for research of tumor drug delivery systems .

HY-143210

Transfectam	Liposome	Metabolic Disease
Transfectam is a cationic lipid able to interact with DNA to form complexes that mediate efficient gene transfer into various eukaryotic cells .

HY-W441015A

DSPE-m-PEG3400-NHS	Liposome	Others
DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .

HY-P5840

Cyclo(RGDyC)	Biochemical Assay Reagents	Cancer
Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer .

HY-145941

AETA 2-Acryloxyethyltrimethylammonium chloride	Biochemical Assay Reagents	Inflammation/Immunology
AETA (2-Acryloxyethyltrimethylammonium chloride) can be used for the synthesis of hydrophilic polymers and hydrogels. Hydrogels are used for membranes, catheters, contact lenses, and drug delivery systems .

HY-142986

Dlin-MeOH	Liposome	Others
Dlin-MeOH is a lipid product for use in drug delivery systems .

HY-148363

Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate	Liposome	Inflammation/Immunology
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .

HY-177846

Liposomal Melatonin	Liposome	Inflammation/Immunology
Liposomal Melatonin is a specialized delivery system that encapsulates melatonin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of melatonin. Melatonin is an antioxidant, anti-inflammatory, fr

HY-109506R

DPPC (Standard) 129Y83 (Standard)	Liposome Reference Standards Endogenous Metabolite	Others
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-177843

Liposomal NMN	Liposome	Metabolic Disease
Liposomal NMN is a specialized delivery system that encapsulates NMN within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of NMN. NMN (β-Nicotinamide Mononucleotide) is a naturally occurring key met

HY-177829

Liposomal Vitamin C	Liposome	Metabolic Disease
Liposomal Vitamin C is a specialized delivery system that encapsulates vitamin C within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin C. Vitamin C (L-ascorbic acid) is a water-soluble vit

HY-145782

Witepsol	Liposome	Metabolic Disease
Witepsol is a selective lipid-based vehicle for use in drug delivery systems .

HY-D2762

18:1 PE AF 594 triammonium	Fluorescent Dye	Cancer
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .

HY-P10560

M918	Biochemical Assay Reagents	Others
M918 is a cell-penetrating peptide. M918 is internalized by cells through endocytosis and can effectively penetrate a variety of cells in a non-toxic manner. M918 can be used in gene therapy and drug delivery system research .

HY-164657

Polyamidoamine (20% in methanol) PAMAM	Radionuclide-Drug Conjugates (RDCs)	Cancer
Polyamidoamine (PAMAM) (20% in methanol) is a new type of drug carrier that has drug encapsulation capabilities internally and biocompatibility on the surface, and can be used as a drug delivery system.

HY-W013122

Cholesteryl n-butyrate Cholesteryl butyrate	Biochemical Assay Reagents	Cancer
Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate .

HY-158255A

mPEG-PLGA (22500-26500)	Biochemical Assay Reagents	Others
mPEG-PLGA (22500-26500) is a biodegradable polymer composed of methyl polyethylene glycol (mPEG) and poly(lactic-co-glycolic acid) (PLGA). mPEG-PLGA (22500-26500) can be used in drug delivery systems .

HY-149664

3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol DC-Chol	Liposome	Cancer
3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .

HY-W160127

N-Hydroxymethyl succinimide N-Methylolsuccinimide	Biochemical Assay Reagents	Others
N-Hydroxymethyl succinimide (N-Methylolsuccinimide) is a promoiety used as a prodrug carrier for non-steroidal anti-inflammatory drugs (NSAIDs). N-Hydroxymethyl succinimide enhances the lipophilicity of NSAIDs and reducing the gastrointestinal toxicity of NSAIDs. N-Hydroxymethyl succinimide is promising for research of anti-inflammatory drug delivery system .

HY-P5033

Cyclo(Gly-His)	Bacterial	Cancer
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC₅₀ values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .

HY-W591449

DOPE-PEG2000-Azide	Liposome	Cancer
DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .

HY-155921

mPEG5000-CHO mPEG5000-Aldehyde	Biochemical Assay Reagents	Others
mPEG5000-CHO participates in the formation of a three-dimensional porous scaffold which carries active substances to form a delivery vehicle. The -CHO functional group interacts with the -NH2 functional group of the chitosan chain to form a glutaraldehyde-type adduct to functionalize mPEG. This functionalization and cross-linking can affect the rigidity of the delivery system, allowing slow release of the cross-linked conjugate system.

HY-112756

PEG2000-DGG	Liposome	Others
PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .

HY-142985

Oleyl Mesylate	Liposome	Metabolic Disease
Oleyl Mesylate is a derivative of Oleyl Alcohol. Oleyl Alcohol has been incorporated into various formulations for drug delivery .

HY-177845

Liposomal Resveratrol	Liposome	Inflammation/Immunology
Liposomal Resveratrol is a specialized delivery system that encapsulates resveratrol within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of resveratrol. Resveratrol is a polyphenol found in plants,

HY-177837

Liposomal Magnesium	Liposome	Metabolic Disease
Liposomal Magnesium is a specialized delivery system that encapsulates inorganic magnesium within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of magnesium. Magnesium is an essential mineral and a

HY-177836

Liposomal Calcium	Liposome	Metabolic Disease
Liposomal Calcium is a specialized delivery system that encapsulates inorganic calcium within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of calcium. Calcium is an essential mineral that plays a c

HY-177835

Liposomal Iron	Liposome	Metabolic Disease
Liposomal Iron is a specialized delivery system that encapsulates inorganic iron within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of iron. Iron is an essential trace element in the human body th

HY-177834

Liposomal Zinc	Liposome	Inflammation/Immunology
Liposomal Zinc is a specialized delivery system that encapsulates zinc compound within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of zinc. Zinc is an important trace element and plays a key role

HY-177842

Liposomal NAD+	Liposome	Metabolic Disease
Liposomal NAD+ is a specialized delivery system that encapsulates NAD+ within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of NAD+. NAD+ (β-Nicotinamide adenine dinucleotide), also known as Coenzym

Cat. No.	Product Name

HY-L214

Liposome Library

191 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 191 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-D0040

Calcein

10+ Cited Publications

Fluorexon

Fluorescent Dye

Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .

HY-N7131

Coumarin 6 20+ Cited Publications	Fluorescent Dye
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-B0315A

Biotin-Vitamin B12

Biotin-Cyanocobalamin B12

Fluorescent Dye

Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is the biotinylated Vitamin B12 (HY-B0315). Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. Biotin-Vitamin B12 can be used in researches on vitamin B12 transport, cellular uptake, targeted delivery, analytical detection, and other areas .

HY-W923645

Fluorescein O,O′-diacrylate

Diacryloyloxyfluorescein

Fluorescent Dye

Fluorescein O,O′-diacrylate (Diacryloyloxyfluorescein) is a fluorescent compound with good biocompatibility and cell labeling ability. Fluorescein O,O′-diacrylate is often used in biological imaging and cell tracking research, and can effectively label cells and track their dynamic changes in vivo. Fluorescein O,O′-diacrylate is also used in compound delivery systems to improve the localization accuracy and inhibitory effect of compounds. Fluorescein O,O′-diacrylate is also used to prepare polymer materials to enhance their optical properties and biological interactions.

HY-D2762

18:1 PE AF 594 triammonium	Fluorescent Dye
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .

HY-N7131R

Coumarin 6 (Standard)	Fluorescent Dye
Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .

HY-DY1091

Calcein (solution)

Fluorexon (solution)

Fluorescent Dye

Calcein (solution) (Fluorexon (solution)) is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
Solvent and concentration: DMSO: 2 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

Cat. No.	Product Name	Target	Research Area

HY-P5423

GALA	Exosomes Liposome	Cancer
GALA is a pH-responsive amphipathic peptide consisting of 30 amino acids, which acts as a lung endothelium-targeting ligand. GALA undergoes a conformational transition from random coil to α-helix in an acidic environment at pH 5.0, thereby inducing endosomal membrane destabilization and fusion. GALA-modified liposomes traverse lung endothelial cells via clathrin-dependent endocytosis and transcytosis, and specifically accumulate in the lungs after intravenous injection. GALA significantly promotes the cytosolic release of cargos carried by exosomes, plasmids and liposomes, effectively enhances gene transfection efficiency, and drives gene knockdown of functional macromolecules (such as siRNA) in alveolar epithelial cells (with no significant cytotoxicity at effective concentrations). GALA serves as a critical tool for studies on lung cancer metastasis (e.g., melanoma lung metastasis) and lung-targeted drug delivery systems .

HY-P10128

GE11 1 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study .

HY-P4121

L17E	Potassium Channel	Inflammation/Immunology Cancer
L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .

HY-160429

PSAR18-COOH	Drug Derivative	Others
PSAR18-COOH is a derivative of PSAR extracted from patent WO2009064913A1. PSAR is a highly hydrophilic, biodegradable, non-immunogenic and water-soluble polymer that has been employed in several delivery systems for drugs or diagnostics.

HY-P10502

L57	LDLR	Infection
L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC₅₀ of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery .

HY-P1848

Pep-1 (uncapped) 2 Publications Verification	Interleukin Related	Cancer
Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma .

HY-P5840

Cyclo(RGDyC)	Biochemical Assay Reagents	Cancer
Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer .

HY-P11423

CSK peptide	Peptides	Others
CSK peptide is a peptide that improves transport of macromolecules across the intestinal mucosal barrier targeting goblet cells. CSK peptide can be used for oral delivery system research .

HY-P10560

M918	Biochemical Assay Reagents	Others
M918 is a cell-penetrating peptide. M918 is internalized by cells through endocytosis and can effectively penetrate a variety of cells in a non-toxic manner. M918 can be used in gene therapy and drug delivery system research .

HY-P4084A

KLA seq acetate	Peptides	Others
KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. KLA seq acetate conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells. KLA seq acetate covalently links targeted mRNA and fluorescein to form a delivery system that has low re-export and is less resistant to serum effects .

HY-P5033

Cyclo(Gly-His)	Bacterial	Cancer
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC₅₀ values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .

HY-P3401

DgHBP-2 HBpep	Peptides	Others
GHGVYGHGVYGHGPYGHGPYGHGLYW (DgHBP-2) is 26-amino-acid-long consensus peptide derived from histidine-rich beak protein-2 (DgHBP-2). GHGVYGHGVYGHGPYGHGPYGHGLYW can be used fabricated glucose-responsive insulin delivery system .

HY-40118

Boc-Pro-OMe Boc-L-proline methyl ester	Liposome	Others
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-P5840A

Cyclo(RGDyC) TFA	Peptides	Cancer
Cyclo(RGDyC) TFA is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) TFA can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer .

HY-P11143

IL4RPep-1	Interleukin Related	Cardiovascular Disease
IL4RPep-1 is a peptide that can specifically target atherosclerotic plaque, and its target is IL-4 receptor. IL4RPep-1 exhibits good plaque targeting and is not enriched in normal tissues. IL4RPep-1 has potential application as a targeting delivery system or molecular imaging probe for atherosclerosis research .

HY-P11186

CALNN	Peptides	Cancer
CALNN is a pentapeptide that can be used as a ligand to stabilise and functionalise gold nanoparticles in drug delivery systems .

HY-P11800A

GPLGVRGC	Exosomes MMP	Inflammation/Immunology
GPLGVRGC is a cysteine-tagged variant of GPLGVRG (HY-P11800). GPLGVRGC is hydrolyzable by MMP13. GPLGVRGC mediates the disassembly of micelle-exosome systems, enhances chondrocyte endocytosis, and promotes responsive system uptake. GPLGVRGC confers targeted delivery and responsive release properties to micelle-exosome systems. GPLGVRGC is applicable to the research of osteoarthritis .

HY-P11800

GPLGVRG	MMP	Inflammation/Immunology
GPLGVRG is an MMP13-responsive linker peptide. GPLGVRG can be hydrolyzed by MMP13, which in turn triggers micellar disintegration, loss of amphipathicity, and increases the chondrocyte uptake rate of the related delivery system. GPLGVRG can be used in the research of osteoarthritis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-109506

DPPC 5+ Cited Publications 129Y83	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Lipid Source Classification	Liposome Endogenous Metabolite
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-N7131

Coumarin 6 20+ Cited Publications	Alkaloids Structural Classification Classification of Application Fields Other Diseases Umbelliferae Plants Disease Research Fields Indole Alkaloids Ambrosia hispida Source Classification	Fluorescent Dye
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-B0315A

Biotin-Vitamin B12 Biotin-Cyanocobalamin B12	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Biotin-Vitamin B12 (Biotin-Cyanocobalamin B12) is the biotinylated Vitamin B12 (HY-B0315). Vitamin B12 is a vitamin that can pass through the blood-brain barrier. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies. Biotin-Vitamin B12 can be used in researches on vitamin B12 transport, cellular uptake, targeted delivery, analytical detection, and other areas .

HY-121447

Heneicosanoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Heneicosanoic acid is an odd-chain saturated fatty acid widely present in human milk, fish, seeds, and cerebrosides in the cell membranes of the nervous system. Heneicosanoic acid can form Langmuir monolayers and is often used as a model to study lipid self-assembly and disassembly processes in biological membranes and drug delivery systems. In the low-temperature L'2 and CS crystalline phases, Heneicosanoic acid undergoes local oscillations, which in turn drive the spontaneous formation and expulsion of micelles and vesicles .

HY-N1446A

Glycerol Monoleate Maximum Cited Publications 60 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Glycerol Monoleate is a non-toxic, biodegradable, biocompatible, lipophilic glycerol fatty acid ester. Glycerol Monoleate exhibits hemolytic properties. Glycerol Monoleate is combined with bile salts for use as an emulsifier and absorption enhancer. Glycerol Monoleate can be applied in drug delivery systems and in vitro siRNA delivery .

HY-137499

NT1-O12B	Alkaloids Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification	Liposome Endogenous Metabolite
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .

HY-109506R

DPPC (Standard) 129Y83 (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Liposome Reference Standards Endogenous Metabolite
DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-W050154R

Kojic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Parasite Tyrosinase NF-κB CDK
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .

HY-N7131R

Coumarin 6 (Standard)	Alkaloids Structural Classification Umbelliferae Plants Indole Alkaloids Ambrosia hispida Source Classification	Fluorescent Dye Reference Standards
Coumarin 6 (Standard) is the analytical standard of Coumarin 6 (HY-N7131). This product is intended for research and analytical applications. Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) .

Cat. No.	Product Name	Chemical Structure

HY-132397S

Phenylephrone-d3 hydrochloride
Phenylephrone-d₃ (hydrochloride) is a deuterium labeled Phenylephrone hydrochloride. Phenylephrone hydrochloride can be used for the phenylephrone chemical delivery systems as safe and effective mydriatic agents .

HY-151994S

1,3-Diolein-d66

1,3-Diolein-d₆₆ is deuterium labeled 1,3-Diolein. 1,3-Diolein is a phospholipid compound that has the activity of regulating cell membrane fluidity and signal transduction. 1,3-Diolein is widely used in cell biology research to study lipid-mediated signal transduction pathways and membrane protein interactions. 1,3-Diolein can also serve as a functional carrier in compound delivery systems to help improve the bioavailability of compounds .

HY-141613S

(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium

(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d₃ ammonium ((2S,8R,19Z)DOPS-d₃ ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .

Cat. No.	Product Name		Classification

HY-160523

DBCO Ir catayst		DBCO
DBCO Ir catalyst is an iridium catalyst labeled with DBCO. DBCO Ir catalyst can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems .

HY-164035

DOPE-PEG2000-DBCO		DBCO
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .

HY-175201

pro-FTY		Azide
pro-FTY, a FTY720 (HY-12005) anticancer prodrug, is a sphingosine-1-phosphate (S1P) (HY-108496) inhibitor. pro-FTY specifically inhibits S1P signaling in cancer cells using a drug delivery system (DDS) that reacts with acrolein. pro-FTY significantly inhibits the survival of breast cancer cells, including multidrug-resistant cells and its organoids resistant to Paclitaxel (HY-B0015) or Doxorubicin (HY-15142A). pro-FTY potently suppresses tumor growth in 4T1 cells or organoids xenograft tumors mice model while avoiding lymphocytopenia .

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