Search Result
Results for "
drinking
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0216
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- HY-19801
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Aldehyde Dehydrogenase (ALDH)
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Neurological Disease
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CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects .
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- HY-A0191
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(+)-Brompheniramine; (S)-Brompheniramine
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Endogenous Metabolite
Histamine Receptor
TRP Channel
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Neurological Disease
Metabolic Disease
Inflammation/Immunology
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Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine can be used in the research of chronic cough and related pathological mechanisms .
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- HY-N0216S1
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Bacterial
Fungal
Endogenous Metabolite
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Infection
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Benzoic acid- 13C6 is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
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- HY-131113
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N-Nitroso-di-n-butylamine
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Caspase
Apoptosis
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Cancer
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N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. N-Nitrosodibutylamine regulates caspase pathway. N-Nitrosodibutylamine induces Apoptosis. N-Nitrosodibutylamine induces hepatocarcinoma and oxidative DNA damage .
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- HY-167856
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GPR88
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Neurological Disease
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RTI-122 is a selective, blood-brain barrier-permeable GPR88 agonist (cAMP EC50=11 nM), with EC50 values of 11.5 nM and 155 nM for human and mouse GPR88, respectively ([ 35S]GTPγS assay). By activating the GPR88 receptor to regulate the cAMP signaling pathway and G protein activity, RTI-122 significantly attenuates Binge-like drinking, reduces alcohol intake, and decreases alcohol-seeking motivation. RTI-122 blocks the reinstatement of alcohol-seeking behavior without affecting water or sucrose intake. RTI-122 exhibits metabolic stability in mice (T1/2=5.8 h) and can be used to investigate alcohol use disorder .
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- HY-B1386
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- HY-131113S
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N-Nitroso-di-n-butylamine-d18
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Isotope-Labeled Compounds
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Others
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N-Nitrosodibutylamine-d18 is the deuterium labeled N-Nitrosodibutylamine . N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water .
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- HY-N0216R
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Reference Standards
Bacterial
Fungal
Endogenous Metabolite
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Infection
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Benzoic acid (Standard) is the analytical standard of Benzoic acid. This product is intended for research and analytical applications. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi .
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- HY-133665
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Drug Derivative
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Others
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2,2-Dibromoacetamide is a class of disinfection by-product (DBP) in drinking water .
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- HY-111469
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Phosphatase
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Metabolic Disease
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CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance .
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- HY-133631
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Drug Derivative
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Others
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Chloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-151217
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RO-71554
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Parasite
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Infection
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Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water .
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- HY-N0216S2
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Bacterial
Fungal
Endogenous Metabolite
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Infection
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Benzoic acid- 13C is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
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- HY-107121
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LY 2196044
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Opioid Receptor
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Neurological Disease
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Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD) .
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- HY-133657
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- HY-133635
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Biochemical Assay Reagents
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Others
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Tribromonitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-P3176
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Motilin Receptor
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Others
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Motilin, human, porcine is a gastrointestinal hormone, which is released during fasting and after eating, or by drinking water. Motilin, human, porcine promotes enteric cholinergic activity in human stomach with an EC50 of 33 nM, and thus modulates gastrointestinal motility function .
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- HY-151217R
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RO-71554 (Standard)
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Reference Standards
Parasite
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Infection
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Ipronidazole (Standard) is the analytical standard of Ipronidazole. This product is intended for research and analytical applications. Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water .
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- HY-W019780
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Dichlorobromomethane
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Glutathione S-transferase
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Metabolic Disease
Cancer
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Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity .
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- HY-B2202R
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Biochemical Assay Reagents
Reference Standards
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Others
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Choline dihydrogen citrate (Standard) is the analytical standard of Choline dihydrogen citrate. This product is intended for research and analytical applications. Choline dihydrogen citrate is a choline-rich hydrochloride that can be absorbed by the body and converted into acetylcholine, which enhances the function of the nervous system and muscles and promotes good health. In addition, this compound is widely used in supplements such as certain energy drinks and protein powders to help improve the body's metabolism and exercise capacity.
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- HY-32833
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Biochemical Assay Reagents
Drug Intermediate
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Others
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2-Chloro-3-pyridinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Chloro-3-pyridinol can also be used in the synthesis of other active compounds. In addition, 2-Chloro-3-pyridinol is a halopyridinol disinfection by-product in drinking water samples .
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- HY-W015487
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Ethyl 3-oxohexanoate
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Biochemical Assay Reagents
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Others
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Ethyl butyrylacetate is an organic compound belonging to the class of esters. Synthesized by the reaction of ethyl acetate, butyric acid and acetic anhydride. Ethyl butyrylacetate has a fruity aroma and is commonly used as a flavoring agent in various food and beverages such as candies, ice cream and soft drinks. It is also used as a fragrance ingredient in perfumes and personal care products. In addition to its use in the food and fragrance industries, Ethyl butyrylacetate is also used in industrial settings, such as in the production of solvents.
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- HY-A0191A
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(+)-Brompheniramine maleate; (S)-Brompheniramine maleate
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TRP Channel
Histamine Receptor
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Inflammation/Immunology
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Dexbrompheniramine ((+)-Brompheniramine; (S)-Brompheniramine) maleate is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine maleate exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine maleate with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine maleate alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine maleate can be used in the research of chronic cough and related pathological mechanisms .
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- HY-133666
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Drug Derivative
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Others
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Diiodoacetamide, a iodo-haloacetamide, is a disinfection by-product (DBP) in drinking water .
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- HY-133647
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Others
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Others
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Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity .
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- HY-133649
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Drug Derivative
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Others
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Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity .
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- HY-P11382
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GABA Receptor
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Neurological Disease
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Octadecaneuropeptide is an 18-residue peptide. Octadecaneuropeptide can be derived from Diazepam binding inhibitor. Octadecaneuropeptide includes a specific ligand for the gamma-aminobutyric acid receptor regulatory site occupied by beta-carbolines. Octadecaneuropeptide elicits a dose-related facilitation of the punishment-
elicited suppression of drinking .
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- HY-133664
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- HY-133636
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Drug Derivative
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Others
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Bromochloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133633
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Biochemical Assay Reagents
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Others
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Bromodichloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-133634
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Biochemical Assay Reagents
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Others
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Dibromochloronitromethane is one of Halonitromethanes, which are a recently identified class of disinfection by-products (DBPs) in drinking water .
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- HY-23399
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Apoptosis
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Others
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Dibromoacetic acid, a haloacetic acid found in drinking water as a disinfection by-product, can cause many adverse effects, including immunotoxicity and apoptosis .
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- HY-133630
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Drug Derivative
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Others
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1-Bromo-1,1-dichloroacetone is one of the clorine doxide dsinfection bproducts (DBPs) in drinking water .
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- HY-133655
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Drug Derivative
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Others
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(E)-2,3-Dibromo-2-butenedioic acid is one of brominated haloacids, which are the drinking water disinfection byproducts (DBPs) .
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- HY-131113S1
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N-Nitroso-di-n-butylamine-d9
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Isotope-Labeled Compounds
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Others
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N-Nitrosodibutylamine-d9 is the deuterium labeled N-Nitrosodibutylamine . N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water .
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- HY-133656
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cis-2-Bromo-3-methylbutenendioic acid
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Biochemical Assay Reagents
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Others
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(Z)-2-Bromo-3-methyl-2-butenedioic acid, one of brominated haloacids, is a disinfection byproduct (DBP) at in finished drinking waters .
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- HY-131113R
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N-Nitroso-di-n-butylamine (Standard)
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Endogenous Metabolite
Reference Standards
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Others
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N-Nitrosodibutylamine (Standard) is the analytical standard of N-Nitrosodibutylamine. This product is intended for research and analytical applications. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water .
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- HY-120144
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Opioid Receptor
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Neurological Disease
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SR-8993 is a highly selective nociceptin receptor agonist that can penetrate the blood-brain barrier and has the activity of reducing alcohol intake and relieving withdrawal anxiety. SR-8993 has shown mild anxiolytic effects in animal models and can effectively reverse anxiety caused by acute alcohol withdrawal. SR-8993 further reduces restricted drinking, operant responses for alcohol, and increased drinking induced by long-term intermittent exposure to alcohol. SR-8993 also reduces stress- and cue-related alcohol-seeking relapse .
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- HY-23399R
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Reference Standards
Apoptosis
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Others
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Dibromoacetic acid (Standard) is the analytical standard of Dibromoacetic acid. This product is intended for research and analytical applications. Dibromoacetic acid, a haloacetic acid found in drinking water as a disinfection by-product, can cause many adverse effects, including immunotoxicity and apoptosis .
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- HY-134564
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Fluorescent Dye
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Others
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Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
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- HY-126910
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Opioid Receptor
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Metabolic Disease
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Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice .
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- HY-11084
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Endogenous Metabolite
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Neurological Disease
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SNAP-7941 is a selective antagonist with anxiolytic, antidepressant and appetite suppressant activities. SNAP-7941 showed promising biological activity in initial animal studies. SNAP-7941 targets the melanin concentrating hormone receptor MCH1 and has significant inhibitory potential. SNAP-7941 was shown to inhibit the centrally induced MCH-induced drinking effect in in vivo studies .
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- HY-W715850
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Ethyl 3-oxohexanoate-d5
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Isotope-Labeled Compounds
Biochemical Assay Reagents
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Others
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Ethyl butyrylacetate-d5 (Ethyl 3-oxohexanoate-d5) is the deuterium labeled Ethyl butyrylacetate (HY-W015487). Ethyl butyrylacetate is an organic compound belonging to the class of esters. Synthesized by the reaction of ethyl acetate, butyric acid and acetic anhydride. Ethyl butyrylacetate has a fruity aroma and is commonly used as a flavoring agent in various food and beverages such as candies, ice cream and soft drinks. It is also used as a fragrance ingredient in perfumes and personal care products. In addition to its use in the food and fragrance industries, Ethyl butyrylacetate is also used in industrial settings, such as in the production of solvents.
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- HY-W274652
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IEM-1770
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iGluR
Drug Derivative
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Neurological Disease
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Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research .
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- HY-W142446
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- HY-181960
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Histamine Receptor
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Neurological Disease
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BP1.3656B is a selective, orally active, blood-brain barrier-permeable histamine H3 receptor (histamine H3 receptor) inverse agonist/antagonist, with a KB value of 0.08 nM for antagonizing agonist-induced activity and an IC50 value of 0.38 nM for directly inhibiting the basal activity of the receptor. BP1.3656B reduces alcohol consumption, alcohol-seeking behavior, alcohol self-administration, motivation to drink, alcohol relapse, alcohol-induced hyperlocomotion, and binge alcohol intake. BP1.3656B is applicable for the research of alcohol use disorder .
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- HY-W751921
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Insecticide
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Others
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Chlorethoxyfos is an organophosphate insecticide. Chlorethoxyfos undergoes oxidation to form its oxon in chlorinated laboratory water .
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- HY-167856A
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GPR88
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Neurological Disease
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RTI-122 dihydrochloride is a selective, blood-brain barrier-permeable GPR88 agonist (cAMP EC50=11 nM), with EC50 values of 11.5 nM and 155 nM for human and mouse GPR88, respectively ([ 35S]GTPγS assay). By activating the GPR88 receptor to regulate the cAMP signaling pathway and G protein activity, RTI-122 dihydrochloride significantly attenuates Binge-like drinking, reduces alcohol intake, and decreases alcohol-seeking motivation. RTI-122 dihydrochloride blocks the reinstatement of alcohol-seeking behavior without affecting water or sucrose intake. RTI-122 dihydrochloride exhibits metabolic stability in mice (T1/2=5.8 h) and can be used to investigate alcohol use disorder .
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- HY-B1803
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ICI 136753
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GABA Receptor
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Neurological Disease
|
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Tracazolate (ICI 136753) is an orally active non-benzodiazepine anxiolytic. Tracazolate significantly enhances the binding of the radioligand 3H-flunitrazepam ( 3H-FLU) to brain tissue benzodiazepine receptors. Tracazolate enhances the binding of γ-aminobutyric acid (GABA) to its receptors. Tracazolate exhibits anticonvulsant activity. Tracazolate can be used in anxiety-related research .
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-
| Cat. No. |
Product Name |
Type |
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- HY-134564
-
|
|
Fluorescent Dye
|
|
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
|
| Cat. No. |
Product Name |
Type |
-
- HY-32833
-
|
|
Biochemical Assay Reagents
|
|
2-Chloro-3-pyridinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Chloro-3-pyridinol can also be used in the synthesis of other active compounds. In addition, 2-Chloro-3-pyridinol is a halopyridinol disinfection by-product in drinking water samples .
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- HY-W015487
-
|
Ethyl 3-oxohexanoate
|
Biochemical Assay Reagents
|
|
Ethyl butyrylacetate is an organic compound belonging to the class of esters. Synthesized by the reaction of ethyl acetate, butyric acid and acetic anhydride. Ethyl butyrylacetate has a fruity aroma and is commonly used as a flavoring agent in various food and beverages such as candies, ice cream and soft drinks. It is also used as a fragrance ingredient in perfumes and personal care products. In addition to its use in the food and fragrance industries, Ethyl butyrylacetate is also used in industrial settings, such as in the production of solvents.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P3176
-
|
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Motilin Receptor
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Others
|
|
Motilin, human, porcine is a gastrointestinal hormone, which is released during fasting and after eating, or by drinking water. Motilin, human, porcine promotes enteric cholinergic activity in human stomach with an EC50 of 33 nM, and thus modulates gastrointestinal motility function .
|
-
- HY-P11382
-
|
|
GABA Receptor
|
Neurological Disease
|
|
Octadecaneuropeptide is an 18-residue peptide. Octadecaneuropeptide can be derived from Diazepam binding inhibitor. Octadecaneuropeptide includes a specific ligand for the gamma-aminobutyric acid receptor regulatory site occupied by beta-carbolines. Octadecaneuropeptide elicits a dose-related facilitation of the punishment-
elicited suppression of drinking .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N0216S1
-
|
|
|
Benzoic acid- 13C6 is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
|
-
-
- HY-131113S
-
|
|
|
N-Nitrosodibutylamine-d18 is the deuterium labeled N-Nitrosodibutylamine . N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water .
|
-
-
- HY-N0216S2
-
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|
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Benzoic acid- 13C is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
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- HY-131113S1
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N-Nitrosodibutylamine-d9 is the deuterium labeled N-Nitrosodibutylamine . N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water .
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- HY-W715850
-
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Ethyl butyrylacetate-d5 (Ethyl 3-oxohexanoate-d5) is the deuterium labeled Ethyl butyrylacetate (HY-W015487). Ethyl butyrylacetate is an organic compound belonging to the class of esters. Synthesized by the reaction of ethyl acetate, butyric acid and acetic anhydride. Ethyl butyrylacetate has a fruity aroma and is commonly used as a flavoring agent in various food and beverages such as candies, ice cream and soft drinks. It is also used as a fragrance ingredient in perfumes and personal care products. In addition to its use in the food and fragrance industries, Ethyl butyrylacetate is also used in industrial settings, such as in the production of solvents.
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| Cat. No. |
Product Name |
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Classification |
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- HY-N0216
-
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Preservatives
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Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi .
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