190 Results for "

macrolide

" in MedChemExpress (MCE) Product Catalog:
Products (190)

190 Results for "macrolide" in MCE Product Catalog:

981
981 Publications Verification
Referencia número: HY-100558
No. CAS: 88899-55-2
Pureza:  99.95%
Synonyms: BafA1
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H +-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .
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60
60 Cited Publications
Referencia número: HY-N6716
No. CAS: 11078-21-0
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
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50
50 Cited Publications
Referencia número: HY-17506
No. CAS: 83905-01-5
Synonyms: CP 62993
Áreas de investigación:  

Infection Cancer

Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
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50
50 Cited Publications
Referencia número: HY-17506A
No. CAS: 117772-70-0
Synonyms: CP-62993 hydrate
Áreas de investigación:  

Infection Cancer

Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
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31
31 Cited Publications
Referencia número: HY-N1724
No. CAS: 80890-47-7
Synonyms: Antibiotic X 4357B; Folimycin; X 4357B
Concanamycin A (Folimycin; Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
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31
31 Cited Publications
Referencia número: HY-N1724A
No. CAS: 80890-47-7
Synonyms: Antibiotic X 4357B (purity≥70%); Folimycin (purity≥70%); X 4357B (purity≥70%)
Concanamycin A (purity≥70%) (Antibiotic X 4357B) is a macrolide antibiotic, a vacuolar type H +-ATPase (V-ATPase) inhibitor. Concanamycin A (purity≥70%) is also an inhibitor of lysosomal acidification, can be used to T cell-mediated inflammation research - .
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29
29 Cited Publications
Referencia número: HY-N6718
No. CAS: 480-49-9
Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis, S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure .
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28
28 Cited Publications
Referencia número: HY-B0220
No. CAS: 114-07-8
Erythromycin is a macrolide antibiotic produced by actinomycete?Streptomyces erythreus?with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits?RNA-dependent protein synthesis?by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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28
28 Cited Publications
Referencia número: HY-B0220A
No. CAS: 3847-29-8
Áreas de investigación:  

Infection Cancer

Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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28
28 Cited Publications
Referencia número: HY-B0220D
No. CAS: 7704-67-8
Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research [3][4].
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8
8 Cited Publications
Referencia número: HY-B0133
No. CAS: 7681-93-8
Synonyms: Pimaricin
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .
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7
7 Cited Publications
Referencia número: HY-B0435
No. CAS: 80214-83-1
Synonyms: RU-28965
Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects .
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6
6 Cited Publications
Referencia número: HY-B0905
No. CAS: 108050-54-0
Synonyms: LY-177370; EL-870
Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .
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6
6 Cited Publications
Referencia número: HY-B0905A
No. CAS: 137330-13-3
Synonyms: LY-177370 phosphate; EL-870 phosphate
Áreas de investigación:  

Infection Inflammation/Immunology

Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects .
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5
5 Cited Publications
Referencia número: HY-A0062
No. CAS: 191114-48-4
Synonyms: HMR3647; RU66647
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection Inflammation/Immunology

Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
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3
3 Cited Publications
Referencia número: HY-N7141
No. CAS: 24916-50-5
Spiramycin I is a macrolide antibiotic and antiparasitic .
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3
3 Cited Publications
Referencia número: HY-105231
No. CAS: 83314-01-6
Pureza:  99.70%
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties .
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2
2 Cited Publications
Referencia número: HY-15662
No. CAS: 217500-96-4
Pureza:  ≥98.0%
Synonyms: Tulathromycin; CP 472295
Target:  

Antibiotic Bacterial

Áreas de investigación:  

Infection

Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC50=0.26 µM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .
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2
2 Cited Publications
Referencia número: HY-B1908
No. CAS: 35457-80-8
Synonyms: SF-837; Antibiotic SF-837
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
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2
2 Cited Publications
Referencia número: HY-128423A
No. CAS: 63409-12-1
Pureza:  99.00%
Synonyms: Acetylisovaleryltylo​sin
Áreas de investigación:  

Infection Inflammation/Immunology Cancer

Tylvalosin (Acetylisovaleryltylo?sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation .
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