18 Results for "

muscle-type

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "muscle-type" in MCE Product Catalog:

Cat. No.: HY-B1532
CAS No.: 494-52-0
Synonyms: (S)-Anabasine; (+)-Anabasine
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
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Cat. No.: HY-P5823
CAS No.: 1391936-86-9
Target:  

nAChR

Research Areas:  

Neurological Disease

Azemiopsin is a potent nicotinic acetylcholine receptor (nAChR) inhibitor with IC50s of 0.18 μM and 22 μM against T. californica nAChR and human α7 nAChR, respectively. Azemiopsin blocks acetylcholine-induced currents in Xenopus oocytes heterologously expressing human muscle-type nAChR .
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Cat. No.: HY-B1532R
CAS No.: 494-52-0
Synonyms: (S)-Anabasine (Standard); (+)-Anabasine (Standard)
Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
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Cat. No.: HY-W014928
CAS No.: 53912-89-3
Synonyms: (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
Target:  

nAChR

Research Areas:  

Neurological Disease

Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
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Cat. No.: HY-126638
CAS No.: 75731-43-0
Synonyms: NSC 324645
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99=0.06 μg/mL) and inhibits motility of adult worms (EC50=2 μM). Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s=0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
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Cat. No.: HY-P700265
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Lung cancer antigen NY-LU-1, muscle-type aldolase
Species:  
Source:  
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Cat. No.: HY-P82292
Synonyms: ALDOA; ALDA; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; muscle-type aldolase

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82292A
Synonyms: ALDOA; ALDA; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; muscle-type aldolase

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7877
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuFructose-bisphosphate aldolase A/ALDOA, His; Fructose-Bisphosphate Aldolase A; Lung Cancer Antigen NY-LU-1; muscle-type Aldolase; ALDOA; ALDA
Species:  
Source:  
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Cat. No.: HY-P71090
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 6-phosphofructokinase; muscle type; Phosphofructo-1-kinase isozyme A; Phosphofructokinase 1; Phosphohexokinase; PFKM; PFKX
Species:  
Source:  
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Cat. No.: HY-P74635
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ATP-dependent 6-phosphofructokinase; ATP-PFK; PFK-M; Phosphohexokinase
Species:  
Source:  
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Cat. No.: HY-P85625
Synonyms: CKM; CKMM; Creatine kinase M; Creatine kinase M chain; Creatine kinase M type; Creatine kinase M-type; Creatine kinase muscle; Creatine kinase, muscle type; KCRM_HUMAN; M-CK; MCK; muscle creatine kinase.

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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Cat. No.: HY-180194
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

SERCA2a activator 2 (Compound 25) is a potent SERCA2a (cardiac type) activator, which also has an activating effect on SERCA1a (skeletal muscle type). SERCA2a activator 2, under [Ca²⁺]MAX conditions activates the ATPase activity of SERCA2a and promotes Ca²⁺ uptake, with its EC₅₀ values being 4 μM and 0.80 μM respectively. SERCA2a activator 2 also exhibits consistent activating effects under more physiological [Ca²⁺]MID conditions. SERCA2a activator 2 has low cytotoxicity and can be used for research on diseases such as heart failure .
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Cat. No.: HY-P85551
Synonyms: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK muscle type; PK, muscle type; PK2; PK3; PKM; PKM2; pykm; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; pyruvate kinase PKM; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK .

Host:  

Mouse

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Monkey

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Cat. No.: HY-P85552
Synonyms: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK muscle type; PK, muscle type; PK2; PK3; PKM; PKM2; pykm; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; pyruvate kinase PKM; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK.

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat, Monkey

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Cat. No.: HY-183204
CAS No.: 326924-19-0
Target:  

nAChR

Research Areas:  

Neurological Disease

TC-2559 is an orally active, selective central nervous system Nicotinic acetylcholine receptor agonist with a Ki value of 5 nM. TC-2559 activates central nervous system receptors selectively over peripheral nervous system receptors. TC-2559 improves scopolamine (HY-N0296)-induced cognitive impairment and enhances radial arm maze performance. TC-2559 can be used in the research of neurodegenerative diseases .
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Cat. No.: HY-P11860
Target:  

nAChR

Research Areas:  

Neurological Disease

WrFr-OCH3 is a competitive nAChR inhibitor, with IC50 values of 291.9 nM, 25.3 nM, 477.5 nM and 36.5 nM against hα1β1εδ nAChR, hα9α10 nAChR, hα7 nAChR and hα9 nAChR, respectively. WrFr-OCH3 exhibits analgesic and muscle relaxant effects, reduces forelimb grip strength in rats, and alleviates Oxaliplatin (HY-17371)-induced cold allodynia in rats. WrFr-OCH3 can be used in studies related to cold allodynia .
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Cat. No.: HY-P83644
Synonyms: PKM2 (Phospho Tyr105); PKM2 (Phospho Y105); PK 1; PK 2; PK 3; PK muscle type; PK1; PK2; Pk3; PKL; PKLR; PKM 2; PKM; PYKM; Pyruvate kinase 1; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozyme R/L; Pyruvate kinase isozymes M1/M2; Pyruvate kinase liver and blood cell; Pyruvate kinase liver and RBC; Pyruvate kinase liver and RBC type; Pyruvate kinase M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; Pyruvate kinase type L; R type/L type pyruvate kinase; Red cell/liver pyruvate kinase; RPK; TCB; THBP 1; THBP1; Thyroid hormone binding protein cytosolic; CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; Tumor M2-PK; p58; OIP-3.

Host:  

Rabbit

Application:  

IHC-P, IHC-F, ICC/IF, FC, ELISA

Reactivity:  

Human, Rat

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