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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
muscle-type
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "muscle-type" in MCE Product Catalog:
Category:
Alkaloids Piperidine Alkaloids Nicotiana tabacum L. Pyridine Alkaloids Plants Solanaceae Extract
Target:
Cat. No.: HY-P5823
CAS No.: 1391936-86-9
Target:
Research Areas:
Cat. No.: HY-W014928
CAS No.: 53912-89-3
Synonyms: (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
Target:
Research Areas:
Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
Category:
Alkaloids Piperidine Alkaloids Nicotiana tabacum L. Pyridine Alkaloids Plants Solanaceae Extract
Target:
Cat. No.: HY-126638
CAS No.: 75731-43-0
Synonyms: NSC 324645
Category:
Alkaloids Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Indole Alkaloids
Target:
Cat. No.: HY-188046
Target:
Research Areas:
AS3566987 is a positive allosteric modulator of the skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3566987 promotes acetylcholine signaling via the skeletal muscle-type nicotinic acetylcholine receptor, and receptor activation requires the involvement of acetylcholine. AS3566987 can be used in the research of neuromuscular diseases (including myasthenia gravis and congenital myasthenic syndrome) .
Cat. No.: HY-P71090
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PFKM; Phosphofructokinase muscle Isoform 4; Prev. PFKX; 6-Phosphofructokinase, muscle type; Phosphofructo-1-Kinase Isozyme A; 6-Phosphofructo-1-Kinase; 6-Phosphofructokinase type A; Phosphofructokinase 1; Phosphohexokinase; Phosphofructokinase-M; PPP1R122
Species:
Human
Source:
HEK293
Cat. No.: HY-188045
Research Areas:
AS3513678 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3513678 promotes acetylcholine (ACh) signaling via m-nAChR, shifts the ACh concentration-response curve to the left, and does not activate the receptor in the absence of ACh. AS3513678 can be used for research on myasthenia gravis and congenital myasthenic syndrome .
Cat. No.: HY-P74635
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PFKM; Phosphofructokinase muscle Isoform 4; Prev. PFKX; 6-Phosphofructokinase, muscle type; Phosphofructo-1-Kinase Isozyme A; 6-Phosphofructo-1-Kinase; 6-Phosphofructokinase type A; Phosphofructokinase 1; Phosphohexokinase; Phosphofructokinase-M; PPP1R122
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-188047
Target:
Research Areas:
AS3580239 is a positive allosteric modulator of skeletal muscle-type nicotinic acetylcholine receptor (m-nAChR). AS3580239 promotes acetylcholine (ACh) signaling via m-nAChR, causing a leftward shift of the ACh concentration-response curve. AS3580239 enhances electrically stimulated isometric contraction of the extensor digitorum longus (EDL) muscle. AS3580239 improves neurotransmission and enhances muscle strength. AS3580239 can be used for research on myasthenia gravis .
Cat. No.: HY-P7459
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ACYP2; ACYP; Acylphosphatase 2; Testicular Tissue Protein Li 11; Acylphosphatase, muscle type Isozyme; HCG2040114, Isoform CRA_a; Acylphosphate Phosphohydrolase 2; Acylphosphatase; Acylphosphatase-2; ACYM; Acylphosphatase 2, muscle type
Species:
Human
Source:
E. coli
Cat. No.: HY-188044
Target:
Research Areas:
DC-98-LC74 is a selective modulator of adult skeletal muscle-type nicotinic acetylcholine receptor (α1β1δε), with an EC50 value of 6.5 µM for the human receptor and an IC50 of 13.45 µM for the human α3β4 nicotinic acetylcholine receptor. DC-98-LC74 increases the ligand-free opening probability of the receptor via the ε subunit M2-M3 loop, and prolongs the burst duration and opening probability of wild-type and fast-channel mutant AChR. DC-98-LC74 exerts weak effects on neuronal AChR subtypes and has no agonist activity. DC-98-LC74 prolongs the mouse diaphragm endplate current and improves muscle contractility in isolated neuromuscular preparations from sarcopenic mice. DC-98-LC74 can be used for studies on neuromuscular junction function and myasthenia-related diseases .
Cat. No.: HY-180194
Target:
Research Areas:
SERCA2a activator 2 (Compound 25) is a potent SERCA2a (cardiac type) activator, which also has an activating effect on SERCA1a (skeletal muscle type). SERCA2a activator 2, under [Ca²⁺]MAX conditions activates the ATPase activity of SERCA2a and promotes Ca²⁺ uptake, with its EC₅₀ values being 4 μM and 0.80 μM respectively. SERCA2a activator 2 also exhibits consistent activating effects under more physiological [Ca²⁺]MID conditions. SERCA2a activator 2 has low cytotoxicity and can be used for research on diseases such as heart failure .
Cat. No.: HY-P85551
Synonyms: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK muscle type; PK, muscle type; PK2; PK3; PKM; PKM2; pykm; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; pyruvate kinase PKM; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK .
Cat. No.: HY-P85552
Synonyms: CTHBP; Cytosolic thyroid hormone binding protein; Cytosolic thyroid hormone-binding protein; KPYM_HUMAN; MGC3932; OIP 3; OIP-3; OIP3; OPA interacting protein 3; Opa-interacting protein 3; p58; PK muscle type; PK, muscle type; PK2; PK3; PKM; PKM2; pykm; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; pyruvate kinase PKM; Pyruvate kinase, muscle 2; TCB; THBP1; Thyroid hormone binding protein 1; Thyroid hormone binding protein cytosolic; Thyroid hormone-binding protein 1; Tumor M2 PK; Tumor M2-PK.
Cat. No.: HY-P83644
Synonyms: PKM2 (Phospho Tyr105); PKM2 (Phospho Y105); PK 1; PK 2; PK 3; PK muscle type; PK1; PK2; Pk3; PKL; PKLR; PKM 2; PKM; PYKM; Pyruvate kinase 1; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozyme R/L; Pyruvate kinase isozymes M1/M2; Pyruvate kinase liver and blood cell; Pyruvate kinase liver and RBC; Pyruvate kinase liver and RBC type; Pyruvate kinase M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; Pyruvate kinase type L; R type/L type pyruvate kinase; Red cell/liver pyruvate kinase; RPK; TCB; THBP 1; THBP1; Thyroid hormone binding protein cytosolic; CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; Tumor M2-PK; p58; OIP-3.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
