27 Results for "

oleanane triterpenoid

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "oleanane triterpenoid" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0819
CAS No.: 89412-79-3
Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma .
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1 Cited Publications
Cat. No.: HY-N0306
CAS No.: 36284-77-2
Hederasaponin B is an orally active oleanane-type triterpenoid saponin and antiviral agent. Hederasaponin B is isolated from the leaves of Acanthopanax senticosus, Hedera nepalensis var. sinensis, and the rhizomes of Souliea vaginata. Hederasaponin B inhibits the expression of the viral capsid protein VP2 and attenuates virus-induced cytopathic effects. Hederasaponin B exhibits activity against Enterovirus 71 subtypes C3 and C4a. Hederasaponin B shows no hepatoprotective effect against CCl4-induced hepatocyte injury. Hederasaponin B is used in research on hand, foot, and mouth disease .
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1 Cited Publications
Cat. No.: HY-N7026
CAS No.: 1807732-38-2
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
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Cat. No.: HY-112671
CAS No.: 1191265-33-4
Purity:  99.71%
Synonyms: RTA dh404
CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB . CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats .
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Cat. No.: HY-N8156
CAS No.: 595-14-2
Soyasapogenol C is an oleanane-type triterpenoid. Soyasapogenol C exhibits anti-HSV-1 activity, with an IC50 of 18.9 μM .
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Cat. No.: HY-N8609
CAS No.: 1262326-46-4
Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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Cat. No.: HY-N7273
CAS No.: 55304-02-4
Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
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Cat. No.: HY-N11068
CAS No.: 96315-52-5
Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
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Cat. No.: HY-N13847
CAS No.: 105038-43-5
Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.
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Cat. No.: HY-N9345
CAS No.: 26926-98-7
(2α,3β)-Olean-12-ene-2,3-diol (Compound 3) is a triterpenoid with lupane, oleanane, and ursane skeleton .
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Cat. No.: HY-N3523
CAS No.: 38337-25-6
3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell line with an IC50 of 13.36 μM .
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Cat. No.: HY-N13115
CAS No.: 35931-54-5
Synonyms: (Z)-Protoescigenin 21-tiglate
21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
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Cat. No.: HY-N13115A
CAS No.: 7047-43-0
Synonyms: (E)-21-Angeloyl-protoaescigenin
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
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Cat. No.: HY-N0819R
CAS No.: 89412-79-3
Raddeanin A (Standard) is the analytical standard of Raddeanin A (HY-N0819). This product is intended for research and analytical applications. Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma.
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Cat. No.: HY-N19898
CAS No.: 1215281-16-5
Raddeanoside R22 is an oleanane-type triterpenoid bisdesmoside saponin found in the rhizome and roots of Anemone raddeana Regel .
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Cat. No.: HY-N21726
CAS No.: 1453187-71-7
Phaseoloideside B is an oleanane-type triterpenoid saponin found in Entada phaseoloides. Phaseoloideside B shows no cytotoxicity against cancer cells .
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Cat. No.: HY-N17570
CAS No.: 135322-63-3
23α-Hydroxy-olean-12-en-3-one (Compound 15) is a pentacyclic triterpenoid, which is a natural derivative of the oleanane skeleton .
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Cat. No.: HY-N17961
CAS No.: 843668-13-3
Synonyms: Septemloside I
Kalopanaxsaponin I (Septemloside I) is an oleanane-type triterpenoid that exists in the fruits of Stauntonia brachyanthera. Kalopanaxsaponin I inhibits LPS (HY-D1056)-induced nitric oxide production in macrophages, with a IC50 of 80.25 μM .
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Cat. No.: HY-N17752
CAS No.: 1453187-72-8
Phaseoloideside C is an oleanane-type triterpenoid saponin. Phaseoloideside C can be isolated from the seeds of *Entada phaseoloides*. Phaseoloideside C exhibits no cytotoxicity against hepatocellular carcinoma cells, esophageal carcinoma cells, cervical carcinoma cells, and colon carcinoma cells .
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Cat. No.: HY-N19755
CAS No.: 80666-65-5
Clemontanoside-C is an oleanane-based triterpenoid saponin and antifungal agent found in the roots of Lepidagathis cuspidata. Clemontanoside-C acts against Aspergillus flavus, Rhizopus stolinifer, Penicillum nodatum, and Aspergillus fumigatus. Clemontanoside-C can be used for the research of fungal infections .
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