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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
149 Results for "
palmitate
" in MedChemExpress (MCE) Product Catalog:
Products (149)
149 Results for "palmitate" in MCE Product Catalog:
149
149 Publications Verification
Cat. No.: HY-50202A
CAS No.: 828934-41-4
Synonyms: (R)-(+)-Etomoxir sodium salt
Research Areas:
Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .
149
Research Areas:
Etomoxir ((R)-(+)-Etomoxir) is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig.
34
34 Cited Publications
K-975 is a potent, selective and orally active TEAD inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma .
12
12 Cited Publications
Target:
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TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth .
5
5 Cited Publications
Target:
Research Areas:
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression .
3
3 Cited Publications
Synonyms: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
3
3 Cited Publications
Target:
Research Areas:
DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca 2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 μM, respectively) . DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis .
3
3 Cited Publications
Synonyms: 1,2-Dilauroyl-sn-glycero-3-phosphocholine
3
3 Cited Publications
Target:
Research Areas:
AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM). AM-1638 increases the expression of antioxidant molecules (HO-1 and NQO-1). AM1638 blocks Palmitate (HY-N0830)-mediated superoxide production and ER stress. AM-1638 has antidiabetic activity and improves glycemic control in BDF mice with diet-induced obesity (DIO). AM-1638 demonstrates excellent oral bioavailability (mouse, >100%; rat, 72%; and cyno, 71%) .
2
1
1 Cited Publications
Synonyms: Vitamin A palmitate; Retinol palmitate
Target:
1
1 Cited Publications
Cat. No.: HY-A0019A
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate
Target:
Research Areas:
Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
1
1 Cited Publications
Cat. No.: HY-P10441A
Target:
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Synonyms: DXP
Target:
Research Areas:
Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation .
Cat. No.: HY-W013168
CAS No.: 1492-30-4
Synonyms: 4-Nitrophenyl hexadecanoate; p-Nitrophenyl palmitate; pNpp
Category:
Verbenaceae Ranunculaceae Lipids Plants Thalictrum acutifolium (Hand.-Mazz.) Boivin Disease Research Fields Inflammation/Immunology Lantana camaraLinn.
Target:
Cat. No.: HY-W011426
CAS No.: 142-91-6
Synonyms: Propan-2-yl hexadecanoate
Cat. No.: HY-168375
CAS No.: 1246809-50-6
Target:
Research Areas:
BODIPY-Palmitate is a fluorescently labeled palmitic acid (HY-N0830), with excitation/emission maxima at 488/508 nm. BODIPY-Palmitate can be used to detect fatty acid uptake and metabolism .
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Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol (HY-B0239), obtained from the esterification reaction between the agent and Palmitic acid (HY-N0830). Chloramphenicol palmitate is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol. Chloramphenicol is an orally effective broad-spectrum antibiotic .
Cat. No.: HY-W010708
CAS No.: 601-34-3
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
