28 Results for "

polyene

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "polyene" in MCE Product Catalog:

57
57 Publications Verification
Cat. No.: HY-17409
CAS No.: 1400-61-9
Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion . Nystatin is a cholesterol-sequestering agent , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis .
loading...
    loading...
53
53 Cited Publications
Cat. No.: HY-N6716
CAS No.: 11078-21-0
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
loading...
    loading...
31
31 Cited Publications
Cat. No.: HY-B0221
CAS No.: 1397-89-3
Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-B2235
CAS No.: 8002-43-5
Synonyms: polyene phosphatidylcholine
Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-K1052

MCE Amphotericin B, Sterile (250 μg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Amphotericin B is a polyene antifungal antibiotic produced by Streptomyces nodosus. It can bind with sterols to form transmembrane channels, resulting in the leakage of intracellular substances, thus inhibiting fungal and yeast contamination.

loading...
    loading...
Cat. No.: HY-106681
CAS No.: 6834-98-6
Purity:  96.14%
Synonyms: Fungichromin; Pentamycin; Cogomycin
Lagosin (Fungichromin) is a polyene macrolide antibiotic. Lagosin has demonstrated broad-spectrum antifungal activity and is impervious to agent resistance .
loading...
    loading...
Cat. No.: HY-DY1017
CAS No.: 11078-21-0
Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718) , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
Solvent and concentration: DMSO: 5 mg/mL
loading...
    loading...
Cat. No.: HY-108874
CAS No.: 1403-17-4
Synonyms: Levorin; Vanobid; Candimon
Research Areas:  

Infection

Candicidin is a polyene antifungal antibiotic agent and can be isolated from Streptomyces griseus or Actinomyces levoris .
loading...
    loading...
Cat. No.: HY-135327
CAS No.: 36148-89-7
Purity:  83.37%
Target:  

HIV Fungal

Research Areas:  

Infection

Amphotericin B methyl ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disrupts HIV-1 particle production and potently inhibits HIV-1 replication .
loading...
    loading...
Cat. No.: HY-125682
CAS No.: 1405-32-9
Target:  

Fungal

Research Areas:  

Infection

Amphotericin A is a tetraenic polyene antifungal agent, produced in the fermentation broth of Amphotericin B (HY-B0221). Amphotericin A has a structure identical to Amphotericin B except for a single bond between carbons 28 and 29 instead of a double bond. Amphotericin A can be used for research on fungal infection .
loading...
    loading...
Cat. No.: HY-125617
CAS No.: 51053-40-8
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

α-Lipomycin is an acyclic polyene antibiotic isolated from the gram-positive bacterium Streptomyces aureofaciens Tü117 .
loading...
    loading...
Cat. No.: HY-B0221A
CAS No.: 1202017-46-6
Amphotericin B trihydrate, a polyene antibiotic, is first isolated from fermenter cultures of Streptomyces nodosus. Amphotericin B trihydrate also possesses antileishmanial activity .
loading...
    loading...
Cat. No.: HY-W160625
CAS No.: 1123-09-7
3,5-Dimethyl-2-cyclohexen-1-one is a precursor to configurationally locked polyene chromophores with a mono-methylated cyclohexene ring .
loading...
    loading...
Cat. No.: HY-B0221R
CAS No.: 1397-89-3
Amphotericin B (Standard) is the analytical standard of Amphotericin B. This product is intended for research and analytical applications. Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
loading...
    loading...
Cat. No.: HY-159666
CAS No.: 34786-70-4
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Nystatin A1 is a polyene macrolide antifungal antibiotic that can be isolated from Streptomyces noursei. Nystatin A1 binds to ergosterol on the fungal cell membrane, increasing the permeability of the cell membrane and causing leakage of cell contents, thereby inhibiting the growth and reproduction of fungi .
loading...
    loading...
Cat. No.: HY-177849
Synonyms: Amphotericin B liposome
Target:  

Liposome Fungal Antibiotic

Research Areas:  

Infection

Liposomal Amphotericin B is a liposome-encapsulated form of Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. Amphotericin B binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death. Liposomal Amphotericin B can significantly reduce the toxicity of Amphotericin B.
loading...
    loading...
Cat. No.: HY-N14979
CAS No.: 51053-36-2
Dermostatin A is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .
loading...
    loading...
Cat. No.: HY-112663
CAS No.: 11006-31-8
Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200 .
loading...
    loading...
Cat. No.: HY-N14980
CAS No.: 51141-40-3
Dermostatin B is a polyene antibiotic with antifungal activity that can be used in the study of fungal infections .
loading...
    loading...
Cat. No.: HY-126783
CAS No.: 77215-53-3
Synonyms: 11-Deoxycandicidin D
Levorin A0 is a Levorin component. Levorin is an aromatic polyene (heptaene) antibiotic with high antifungal activity.
loading...
    loading...