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primary follicles

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-106591A
    4-Vinylcyclohexene dioxide

    Vinylcyclohexene diepoxide

    		 Environmental Pollutants Akt Apoptosis mTOR Reactive Oxygen Species (ROS) PI3K Endocrinology
    4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .
    4-Vinylcyclohexene dioxide
  • HY-106591AR
    4-Vinylcyclohexene dioxide (Standard)

    Vinylcyclohexene diepoxide (Standard)

    		 Reference Standards Apoptosis Reactive Oxygen Species (ROS) PI3K Akt mTOR Endocrinology
    4-Vinylcyclohexene dioxide (Standard) is the analytical standard of 4-Vinylcyclohexene dioxide (HY-106591A). This product is intended for research and analytical applications. 4-Vinylcyclohexene dioxide (4-Vinylcyclohexene diepoxide) is an orally active metabolite of 4-vinylcyclohexene. 4-Vinylcyclohexene dioxide induces Apoptosis, increases intracellular ROS, and activates the PI3K/Akt/mTOR pathway. 4-Vinylcyclohexene dioxide selectively damages small ovarian follicles, inhibits granulosa cell function, and disrupts the male reproductive system. 4-Vinylcyclohexene dioxide can be used in the study of premature ovarian insufficiency, reproductive toxicity, and related fertility disorders .
    4-Vinylcyclohexene dioxide (Standard)
  • HY-W673613
    ADX68692

    		Estrogen Receptor/ERR Metabolic Disease
    ADX68692 is an orally active negative allosteric modulators of follicle-stimulating hormone receptor with a log IC50 of -5.71. ADX68692 can inhibit hCG-induced cAMP production and s ß-arrestin 2 recruitment in HEK293 cells. ADX68692 exhibits a partial effect in both mLTC-1 and primary rat Leydig cells. ADX68692 inhibits FSHR-promoted cAMP, progesterone and estradiol production. ADX68692 can reduce the number of oocytes recovered from the ampullae .
    ADX68692

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