85 Results for "

progressive

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "progressive" in MCE Product Catalog:

184
184 Publications Verification
Referencia número: HY-16561
No. CAS: 501-36-0
Synonyms: trans-Resveratrol; SRT501
Resveratrol (trans-Resveratrol; SRT501) is a CNS-penetrant natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator . Resveratrol is a potent pregnane X receptor (PXR) inhibitor . Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model . Resveratrol increases production of NO in endothelial cells .
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81
81 Cited Publications
Referencia número: HY-P7117
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1; CAEND1; Transforming Growth Factor, Beta 1; LAP; Diaphyseal Dysplasia 1, progressive; Transforming Growth Factor Beta 1; Transforming Growth Factor Beta
Species:  
Rat Mouse
Source:  
HEK293
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7
7 Cited Publications
Referencia número: HY-109192
No. CAS: 1971920-73-6
Pureza:  99.79%
Synonyms: SAR442168; PRN2246
Target:  

Btk

Áreas de investigación:  

Neurological Disease Inflammation/Immunology

Tolebrutinib (SAR442168) is an orally active, selective, and blood-brain barrier-penetrant BTK inhibitor with neuroactive properties. Tolebrutinib is being investigated for use in multiple sclerosis (MS), particularly secondary progressive multiple sclerosis (SPMS). .
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7
7 Cited Publications
Referencia número: HY-P78168
Pureza:  ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1; CAEND1; Transforming Growth Factor, Beta 1; LAP; Diaphyseal Dysplasia 1, progressive; Transforming Growth Factor Beta 1; Transforming Growth Factor Beta
Species:  
Human
Source:  
HEK293
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6
6 Cited Publications
Referencia número: HY-P70781
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial progressive Hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:  
Human
Source:  
E. coli
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4
4 Cited Publications
Referencia número: HY-B0964
No. CAS: 130-40-5
Synonyms: Riboflavine phosphate sodium; Riboflavin 5'-phosphate sodium; Riboflavine 5'-phosphate sodium
Riboflavin phosphate sodium (FMN-Na) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavin phosphate sodium can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism . Riboflavine phosphate sodium is a very effective NAD +-recycling agent .
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3
3 Cited Publications
Referencia número: HY-15897
No. CAS: 1432597-26-6
Pureza:  99.70%
Target:  

TGF-β Receptor

Áreas de investigación:  

Cancer

LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC50: 1.3 nM). LDN-212854 also inhibits ALK1 (IC50: 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC) .
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3
3 Cited Publications
Referencia número: HY-18932
No. CAS: 181223-80-3
Target:  

ERK Apoptosis

Áreas de investigación:  

Cancer

DEL-22379 is an ERK dimerization Inhibitor. DEL-22379 readily binds to ERK2 with a Kd estimated in the low micromolar range, though binding is detectable even at low nanomolar concentrations. ERK2 dimerization is progressively inhibited with an IC50 of ~0.5 μM.
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3
3 Cited Publications
Referencia número: HY-P70528
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial progressive Hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:  
Mouse
Source:  
E. coli
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3
3 Cited Publications
Referencia número: HY-P70555
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial progressive Hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:  
Mouse
Source:  
HEK293
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3
3 Cited Publications
Referencia número: HY-P78213
Pureza:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1; CAEND1; Transforming Growth Factor, Beta 1; LAP; Diaphyseal Dysplasia 1, progressive; Transforming Growth Factor Beta 1; Transforming Growth Factor Beta
Species:  
Human
Source:  
HEK293
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3
3 Cited Publications
Referencia número: HY-P78668
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1; CAEND1; Transforming Growth Factor, Beta 1; LAP; Diaphyseal Dysplasia 1, progressive; Transforming Growth Factor Beta 1; Transforming Growth Factor Beta
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Referencia número: HY-13010
No. CAS: 248281-84-7
Pureza:  99.46%
Synonyms: ABR-215062
Target:  

NF-κB Apoptosis

Áreas de investigación:  

Inflammation/Immunology

Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research .
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2
2 Cited Publications
Referencia número: HY-P70433
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB1; Transforming Growth Factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; Transforming Growth Factor Beta-1 Proprotein; IBDIMDE; Prepro-Transforming Growth Factor Beta-1; CAEND1; Transforming Growth Factor, Beta 1; LAP; Diaphyseal Dysplasia 1, progressive; Transforming Growth Factor Beta 1; Transforming Growth Factor Beta
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Referencia número: HY-132613
No. CAS: 1834612-06-4
Pureza:  99.21%
Áreas de investigación:  

Metabolic Disease

Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
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1
1 Cited Publications
Referencia número: HY-123178
No. CAS: 39515-41-8
Pureza:  99.86%
Áreas de investigación:  

Neurological Disease

Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively .
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1
1 Cited Publications
Referencia número: HY-107428
No. CAS: 199850-67-4
Pureza:  99.21%
Target:  

MMP

Áreas de investigación:  

Cardiovascular Disease

PD-166793 is a potent, selective, orally active and wide-broad spectrum inhibitor of MMP, exhibiting nanomolar potency against MMP-2, MMP-3 and MMP-13 (IC50=4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1, -7 and -9 (IC50=6.0, 7.2, and 7.9 μM, respectively). PD-166793 can attenuate left ventricular remodeling and dysfunction in a rat model of progressive heart failure .
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1
1 Cited Publications
Referencia número: HY-P72965
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSTB; Cystatin B (Stefin B); Prev. STFB; CPI-B; Prev. EPM1; Epididymis Secretory Sperm Binding Protein; CST6; Epilepsy, progressive Myoclonic 1; Cystatin-B; Stefin B; PME; EPM1A; Liver Thiol Proteinase Inhibitor; ULD; Cystatin B; Stefin-B
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Referencia número: HY-P70757G
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KITLG; SLF; Prev. MGF; Familial progressive Hyperpigmentation 2; SCF; Steel Factor; Mast Cell Growth Factor; C-Kit Ligand; Stem Cell Factor; Kit Ligand; DFNA69; SHEP7; Kitl; DCUA; KL-1; FPHH; FPH2; WS2F; KIT Ligand; SF
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Referencia número: HY-P75333
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: COL2A1; Alpha-1 Collagen Type II; Prev. SEDC; Chondrocalcin; Prev. AOM; SEMDSTWK; STL1; COL11A3; Arthroophthalmopathy, progressive (Stickler Syndrome); SEDSTN; Collagen, Type II, Alpha 1; SMDALG; Collagen Alpha-1(II) Chain; ANFH1; Alpha-1 Type II Collagen
Species:  
Human
Source:  
HEK293
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