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Results for "

root extract

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Amyloid-β (2) Apoptosis (10) Autophagy (2) Bacterial (2) Biochemical Assay Reagents (3) C-type Lectin-like Receptors (CTLRs) (2) Carboxylesterase (CES) (1) Dengue Virus (2) Drug Derivative (1) Drug Metabolite (2) EBV (1) Environmental Pollutants (3) Glycosidase (3) Interleukin Related (2) Isotope-Labeled Compounds (2) JNK (3) NF-κB (7) NO Synthase (1) NOD-like Receptor (NLR) (2) Phytohormone (1) Potassium Channel (2) PPAR (2) Prolyl Endopeptidase (PREP) (2) RANKL/RANK (2) Reference Standards (8) STAT (2)
By Research Areas:	Cancer (15) Cardiovascular Disease (4) Infection (6) Inflammation/Immunology (14) Metabolic Disease (4) Neurological Disease (5)

By Targets:

5-HT Receptor (1)

Amyloid-β (2)

Apoptosis (10)

Autophagy (2)

Bacterial (2)

Biochemical Assay Reagents (3)

C-type Lectin-like Receptors (CTLRs) (2)

Carboxylesterase (CES) (1)

Dengue Virus (2)

Drug Derivative (1)

Drug Metabolite (2)

EBV (1)

Environmental Pollutants (3)

Glycosidase (3)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

JNK (3)

NF-κB (7)

NO Synthase (1)

NOD-like Receptor (NLR) (2)

Phytohormone (1)

Potassium Channel (2)

PPAR (2)

Prolyl Endopeptidase (PREP) (2)

RANKL/RANK (2)

Reference Standards (8)

STAT (2)

By Research Areas:

Cancer (15)

Cardiovascular Disease (4)

Infection (6)

Inflammation/Immunology (14)

Metabolic Disease (4)

Neurological Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-32735

Triptolide Maximum Cited Publications 70 Publications Verification PG490	Environmental Pollutants NF-κB Apoptosis	Cancer
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-N0145

Puerarin 25+ Cited Publications	5-HT Receptor	Cardiovascular Disease Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption .

HY-N0174

Cryptotanshinone 45+ Cited Publications Cryptotanshinon; Tanshinone c	STAT Autophagy	Cancer
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC₅₀ of 4.6 μM.

HY-N6973

Boldine 1 Publications Verification	RANKL/RANK Apoptosis	Inflammation/Immunology Cancer
Boldine is an apomorphine isoquinoline alkaloid extracted from the root of the pheasant pepper (Litsea cubeba). Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3β. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research .

HY-N0373

Licochalcone B 10+ Cited Publications	Amyloid-β Apoptosis NOD-like Receptor (NLR)	Neurological Disease
Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (₄₂) self-aggregation (IC₅₀=2.16 μM) and disaggregate pre-formed Aβ₄₂ fibrils, reduce metal-induced Aβ₄₂ aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .

HY-N2481

Oroxylin A-7-O-glucuronide 1 Publications Verification Oroxyloside; Oroxylin A-7-O-β-D-glucuronide	Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .

HY-136302

Karrikinolide	Phytohormone	Others
Karrikinolide is a plant-active compound. Karrikinolide can be extracted from smoke water (SW). Karrikinolide promotes total Cytokinin production. Plants treated with Karrikinolide exhibit superior growth in terms of rooting, leaf and bulb size, and fresh weight .

HY-W250120

Konjac glucomannan (Viscosity≥15000mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Konjac glucomannan (Viscosity≥15000mPa.s) is an acetylated (1-4)-beta-D-glucomannan extracted from the tuber of konjac or konjac root. In Japan, it is a dietary supplement intended to reduce calorie intake because it swells in water.

HY-N0434

Astragaloside III 2 Publications Verification	C-type Lectin-like Receptors (CTLRs) Apoptosis Dengue Virus	Infection Cancer
Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .

HY-W016289

Antiarol 3,4,5-Trimethoxyphenol	Glycosidase	Others
Antiarol (3,4,5-Trimethoxyphenol) is a natural compound. Antiarol can be extracted from Cochlospermum vitifolium. Antiarol can be used to study plant seed germination and root and hypocotyl growth .

HY-N10686

Tanshinone IIA anhydride	Carboxylesterase (CES)	Cancer
Tanshinone IIA anhydride, present in root extracts of Salvia miltiorrhiza, acts as an inhibitor of human carboxylesterase (CE). Tanshinone IIA anhydride has a K_i value of 1.9 nM against hCE1 and a K_i value of 1.4 nM against hiCE. Tanshinone IIA anhydride forms a stable covalent complex with serine Ser221 at the active site of hCE1, blocking the catalytic cycle of carboxylesterase, and the activity of the inactivated enzyme cannot recover spontaneously. Tanshinone IIA anhydride is applicable in metabolism-related studies .

HY-32735S

Triptolide-d3 PG490-d₃	Isotope-Labeled Compounds NF-κB Apoptosis	Cancer
Triptolide-d₃ is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-N8761

Kihadanin A	NO Synthase	Metabolic Disease
Kihadanin A (compound 3) is a limonoid NOS3 inhibitor that can be isolated from the methanol extract of Dictamnus dasycarpus root bark. Kihadanin A is useful in the study of hyperuricemia (HUA) [3].

HY-32735R

Triptolide (Standard) PG490 (Standard)	Reference Standards NF-κB Apoptosis	Cancer
Triptolide (Standard) is the analytical standard of Triptolide. This product is intended for research and analytical applications. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-N6973R

Boldine (Standard) 1 Publications Verification	Reference Standards RANKL/RANK	Inflammation/Immunology
Boldine (Standard) is the analytical standard of Boldine. This product is intended for research and analytical applications. Boldine is an aporphine isoquinoline alkaloid extracted from the root of Litsea cubeba and also possesses these properties, including antioxidant, anti-inflammatory and cytoprotective effects. Boldine suppresses osteoclastogenesis, improves bone destruction by down-regulating the OPG/RANKL/RANK signal pathway and may be a potential therapeutic agent for rheumatoid arthritis .

HY-N2205

Esculentoside H 2 Publications Verification	NF-κB JNK	Cancer
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .

HY-P3071

ShK toxin Stichodactyla helianthus neurotoxin	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation .

HY-107918

Alkaloids, Rauwolfia	Others	Cardiovascular Disease
Alkaloids, Rauwolfia is an extract of the whole root of Rauwolfia serpentina with antihypertensive effect .

HY-N10603

Praeroside Baihuaqianhuoside	Others	Inflammation/Immunology
Praeroside (Baihuaqianhuoside), a coumarin glycoside. Praeroside can be extracted from the root of Peucedanum praeruptorum and Heracleum dissectum. Praeroside shows anti-inflammatory activity in vitro. Praeroside can be used for the research of inflammation .

HY-N11020

Cabenoside D	EBV	Infection Inflammation/Immunology
Cabenoside D (compound 8) is a triterpenoid glycoside, which can be isolated from the methanol extract of lichen root. Cabenoside D shows anti-inflammatory activity and inhibits inflammation induced by 12-O-tetracylacyl hormone-13-acetate (TPA) in mice. Cabenoside D also inhibits TPA-induced Epstein-Barr virus (EBV) early antigen (EBV-EA) activation .

HY-W017241

1-Naphthalenemethanol 1-Hydroxymethylnaphthalene	Bacterial Biochemical Assay Reagents	Infection
1-Naphthalenemethanol is a hydroxyl-substituted naphthalene derivative. 1-Naphthalenemethanol can be extracted from the root of Annona senegalensis. 1-Naphthalenemethanol is a photolysis product of 1-napthaleneacetic acid. 1-Naphthalenemethanol, together with PAPS, provides some protection against the irreversible inactivation of AST IV caused by N-OH-2AF. 1-Naphthalenemethanol can be used in antibacterial research .

HY-N7399

Dipalmitin	Environmental Pollutants	Others
Dipalmitin is an active product that can be extracted from root tuber of Typhonium giganteum Engl. Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid Palmitic acid (HY-N0830) at two positions .

HY-P3071A

ShK toxin TFA Stichodactyla helianthus neurotoxin TFA	Potassium Channel	Neurological Disease Inflammation/Immunology
ShK toxin TFA (Stichodactyla helianthus neurotoxin TFA) is a neurotoxin. ShK toxin TFA blocks voltage-dependent potassium channel (K_v1.3 channel). ShK toxin TFA can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin TFA competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin TFA suppresses K ⁺ currents in cultured rat dorsal root ganglion neurons. ShK toxin TFA also inhibits T lymphocyte proliferation .

HY-N2481R

Oroxylin A-7-O-glucuronide (Standard) Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)	Reference Standards Prolyl Endopeptidase (PREP) Drug Metabolite JNK PPAR NF-κB Interleukin Related	Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide (HY-N2481). This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .

HY-N19046

Rehmannia root extract	Others	Others
Rehmannia Root Extract is derived from the root tuber of Rehmannia glutinosa Libosch. It contains catalpol, a variety of amino acids and sugars, mannitol, β-sitosterol and campesterol.

HY-N18691

Scutellaria baicalensis root extract	Others	Inflammation/Immunology
Scutellaria Baicalensis Root Extract is a plant cosmetic raw material obtained from the dried root of Scutellaria baicalensis Georgi. Scutellaria Baicalensis Root Extract mainly contains two flavonoid active ingredients, baicalin and baicalein, which has strong biological activity and is a multi-effect cosmetic additive.

HY-N18672

Valerian root solid extract	Others	Others
Valerian root solid extract is a substance extracted from the rhizome of valerian (Valeriana officinalis) and is commonly used in health products, pharmaceuticals, and cosmetics.

HY-N12365

Ginsenoside Rs2	Others	Others
Ginsenoside Rs2 is extracted from Panax ginseng root .

HY-N8662

Primulic acid II	Others	Inflammation/Immunology
Primulic acid II is a saponin isolated from root extract of Primula sp .

HY-N5154

Sanggenon W	Others	Others
Sanggenon W is an isoprenyl flavonoid extracted from mulberry root bark .

HY-N7341

8-Deacetylyunaconitine	Others	Others
8-Deacetylyunaconitine, a diterpenoid alkaloid, can be found in the root extract of A. forrestii .

HY-N12014

Triptotriterpenic acid C	Others	Others
Triptotriterpenic acid C is a ursolic-type acid that can be isolated from total glycosides extracted from the root of Tripterygium wilfordii Hook.f. .

HY-119637

Frangufoline	Others	Others
Frangufoline is a 4(14)-type cyclopeptide alkaloid, that can be isolated from the root bark extract of Ziziphus cambodiana Pierre .

HY-N9478

Sumaresinolic acid	Glycosidase	Others
Sumaresinolic acid (compound 6) is a natural product which can be extracted from heterophyllum root . Sumaresinolic acid is a alpha-glucosidase inhibitor .

HY-N12579

Desacylsenegasaponin B	Others	Inflammation/Immunology
Desacylsenegasaponin B is an active product that can be extracted from root of Polygala tenuifolia. Desacylsenegasaponin B has potential anti-inflammatory activity .

HY-N12575

Physcion-8-O-(6'-O-malonyl)-glucoside	Others	Others
Physcion-8-O-(6'-O-malonyl)-glucoside can be extracted from the root tuber of Polygonum multiflorum Thunb .

HY-N1770

12-Hydroxysapriparaquinone 3,4-Didehydrosapriparaquione	Others	Others
12-Hydroxysapriparaquinone (compound 8) is a rearranged 4,5-seco-abietane diterpenoid isolated from the petroleum ether extract of the root of Salvia rhytidea .

HY-N0174R

Cryptotanshinone (Standard) Cryptotanshinon (Standard); Tanshinone c (Standard)	Reference Standards STAT Autophagy	Cancer
Cryptotanshinone (Standard) is the analytical standard of Cryptotanshinone. This product is intended for research and analytical applications. Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC₅₀ of 4.6 μM.

HY-W654377

Triptolide-d3 (major) (>90%)	Isotope-Labeled Compounds Apoptosis NF-κB	Cancer
Triptolide-d₃ (major) (>90%) is the deuterium labeled Triptolide (HY-32735). Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .

HY-N2939

Bis-5,5-Nortrachelogenin	Others	Others
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM .

HY-N2132R

Flavokawain B (Standard) Flavokavain B (Standard)	Reference Standards Apoptosis	Cancer
Flavokawain B (Standard) is the analytical standard of Flavokawain B. This product is intended for research and analytical applications. Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B (Flavokavain B) shows strong antiangiogenic activity. Flavokawain B (Flavokavain B) inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations .

HY-N0434R

Astragaloside III (Standard)	Reference Standards C-type Lectin-like Receptors (CTLRs) Apoptosis Dengue Virus	Infection Cancer
Astragaloside III (Standard) is the analytical standard of Astragaloside III (HY-N0434). This product is intended for research and analytical applications. Astragaloside III is a triterpenoid saponin. Astragaloside III can be extracted from Astragalus root. Astragaloside III increases NKG2D and induces TACE phosphorylation. Astragaloside III induces Apoptosis. Astragaloside III has antiviral activity against dengue serotypes 1 and 3. Astragaloside III has anticancer activity against breast and colon cancer .

HY-W017241R

1-Naphthalenemethanol (Standard) 1-Hydroxymethylnaphthalene (Standard)	Reference Standards Bacterial Biochemical Assay Reagents	Infection
1-Naphthalenemethanol (Standard) is the analytical standard of 1-Naphthalenemethanol (HY-W017241). This product is intended for research and analytical applications. 1-Naphthalenemethanol is a hydroxyl-substituted naphthalene derivative. 1-Naphthalenemethanol can be extracted from the root of Annona senegalensis. 1-Naphthalenemethanol is a photolysis product of 1-napthaleneacetic acid. 1-Naphthalenemethanol, together with PAPS, provides some protection against the irreversible inactivation of AST IV caused by N-OH-2AF. 1-Naphthalenemethanol can be used in antibacterial research .

HY-N0373R

Licochalcone B (Standard)	Reference Standards Amyloid-β Apoptosis NOD-like Receptor (NLR)	Neurological Disease
Licochalcone B (Standard) is the analytical standard of Licochalcone B. This product is intended for research and analytical applications. Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .

HY-N8737

Desrhamnosylmartynoside	Others	Others
Desrhamnosylmartynosideis extracted from the root of Scutellaria prostrata. Desrhamnosylmartynoside has absorption bands assignable to hydroxyl,α,β-unsanturate carbonyl groups .

HY-N17537

Norwogonin-7-O-glucoside	Drug Derivative	Others
Norwogonin-7-O-glucoside is a flavonoid found in the root of Scutellaria discolor COLEBR .

HY-N17559

Praeroside V	Others	Others
Praeroside V is an angular-type pyranocoumarm glycoside. Praeroside V can be isolated from the n-butanol extracts of Bai-Hua Qian-Hu, the root of Peucedanum praeruptorum Dunn .

HY-N19073

Picrorrhiza kurroa extract	Others	Inflammation/Immunology
Picrorrhiza kurroa extract is derived from the root of the Picrorrhiza kurroa plant. Its active ingredients include matrine I, matrine II, oleanolic acid, and triterpenoids, which give it hepatoprotective, anti-inflammatory, antioxidant, and immunomodulatory effects.

HY-N18182

Mudanpioside E	Glycosidase	Inflammation/Immunology
Mudanpioside E is an orally effective paeoniflorin-type monoterpene glycoside antiallergic agent, with an IC₅₀ of 40.34 μM against IgE-mediated β-hexosaminidase release. Mudanpioside E reverses the inhibitory effect of the modified Xiaoqinglong Decoction extract (paeonia root component removed) on passive cutaneous anaphylaxis in mice. Mudanpioside E itself shows no activity against passive cutaneous anaphylaxis. Mudanpioside E can be used in research related to allergic diseases .

HY-N17966

Puerarin-6"-O-glucoside	Others	Others
Puerarin-6"-O-glucoside (Compound 2) is an isoflavonoid compound that can be isolated from the roots of Pueraria lobata (Wild.) Ohwi .

Cat. No.	Product Name	Target	Research Area