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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
super-resolution imaging
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "super-resolution imaging" in MCE Product Catalog:
1
Cat. No.: HY-D2348A
Cat. No.: HY-D2348
CAS No.: 3058751-62-2
Cat. No.: HY-W784030
CAS No.: 1380349-88-1
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N-TCO-L-lysine is a non-canonical amino acid. N-TCO-L-lysine contains a trans-cyclooctene (TCO) bioorthogonal reactive linker. N-TCO-L-lysine undergoes a bioorthogonal click reaction with SiR-Tz to enable fluorescent labeling of endogenously expressed proteins with site-specific incorporation. When used in combination with SiR-Tz, N-TCO-L-lysine allows super-resolution and live-cell imaging of endogenous proteins .
Cat. No.: HY-W400925
CAS No.: 1481447-40-8
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Sulfo-Cy5-N3 is an azide-functionalized sulfonated cyanine 5 Fluorescent dye and also serves as click chemistry coupling reagent. Sulfo-Cy5-N3 undergoes copper (I)-catalyzed azide-alkyne cycloaddition with alkyne-functionalized antibody constructs and peptide probes for site-selective fluorescent labeling. Sulfo-Cy5-N3 also acts as an emission dye for STORM super-resolution imaging. Sulfo-Cy5-N3 is applicable to the study of HER2-positive breast cancer .
Cat. No.: HY-D2417
CAS No.: 2365417-91-8
Cat. No.: HY-D1305
CAS No.: 1443553-08-9
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ATTO 488 carboxylic acid is a bright green fluorescent dye with high photostability, which is commonly used in protein fluorescent labeling, single-molecule fluorescence imaging and super-resolution microscopy studies. The carboxylic acid form of ATTO 488 can be covalently coupled to primary amines of proteins via activation, or prepared into a maleimide derivative for coupling with thiol groups; it emits green fluorescence after labeling. Ex/Em = 488/524 nm .
Cat. No.: HY-D2002
CAS No.: 1219127-42-0
Cat. No.: HY-D2923
CAS No.: 1811539-43-1
Cat. No.: HY-D2183
CAS No.: 1811539-31-7
Cat. No.: HY-D2953
Synonyms: CLIP-CPY
Cat. No.: HY-D2954
CAS No.: 1108751-16-1
Synonyms: CLIP-PEG-NH2
Cat. No.: HY-D3366
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Th-TMR-S-Halo is a fluorescent probe for HaloTag labeling and live-cell imaging, including super-resolution imaging and real-time visualization of endoplasmic reticulum (ER) vortex formation under ER stress conditions. Th-TMR-S-Halo shows weak fluorescence in the free state, and upon covalent binding to HaloTag, fluorescence activation is achieved by restricting the rotation of the thiophene ring. Th-TMR-S-Halo can be used in studies related to intracellular protein localization, cytoskeleton structure, and ER vortex formation. Live-cell NSPARC super-resolution detection is performed using Ex/Em = 561/570-616 nm .
Cat. No.: HY-D3570
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AF405 DBCO is a blue fluorescent dye derivative containing a dibenzocyclooctyne (DBCO) group. AF405 DBCO reacts rapidly with azide-labeled biomolecules at room temperature without the need for a metal catalyst, enabling copper-free click chemistry (SPAAC) for applications in live-cell imaging, flow cytometry, super-resolution microscopy, and other research fields .
Cat. No.: HY-D3438
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Photoswitchable PM8 is a fluorescent probe used for super-resolution imaging of the plasma membrane. Photoswitchable PM8 functions through a light-induced Z/E isomerization mechanism: in the hydrophobic cell membrane environment, the Z isomer forms a planar intramolecular charge transfer state stabilized by an intramolecular hydrogen bond, which restricts conformational freedom, reduces nonradiative decay, and produces bright fluorescence; in contrast, the E isomer lacks this hydrogen bond, has increased conformational freedom, and exhibits a fluorescence-quenched state. The fluorescence of Photoswitchable PM8 can be switched "on/off" by visible light: activation with 405 nm light forms the fluorescent Z isomer, and switching with 561 nm light converts it to the nonfluorescent E isomer. In the membrane environment, Photoswitchable PM8 enables single-molecule localization for super-resolution imaging. Due to solvent-induced quenching and aggregation, Photoswitchable PM8 has negligible fluorescence in aqueous solution, but upon binding to the hydrophobic membrane environment it produces bright fluorescence, enabling high signal-to-noise ratio imaging without washing .
Cat. No.: HY-D3240
CAS No.: 2375541-43-6
Cat. No.: HY-D3437
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LRhod-PM is a photo-activated plasma membrane fluorescent probe based on a self-initiating photo-oxidation cascade mechanism. LRhod-PM, a non-fluorescent reduced rhodamine, is oxidized to the fluorescent form Rhod-PM upon visible light irradiation. LRhod-PM has maximum excitation and emission wavelengths of 560 nm and 585 nm, respectively. LRhod-PM enables wash-free labeling of the plasma membrane of living cells, including fine structures such as filopodia and tunneling nanotubes. LRhod-PM can be used in studies related to single-molecule localization super-resolution imaging of living cells .
Cat. No.: HY-D3148
CAS No.: 1804107-88-7
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TPE-Ph-In is a mitochondria-targeted voltage-sensitive probe that can be used for mitochondrial membrane potential detection, mitochondrial imaging of animal and plant cells and tissues, mouse sperm activity indication, and detection of mitochondrial membrane potential changes associated with early apoptosis. TPE-Ph-In is non-fluorescent in solution, but emits strong fluorescence when aggregated via restriction of intramolecular rotation/movement, and its fluorescence intensity is directly correlated with local probe concentration or mitochondrial membrane potential level. TPE-Ph-In can penetrate cell membranes, target mitochondria through charge-dependent accumulation, has low cytotoxicity and high photostability, and enables super-resolution imaging of plant mitochondrial fission, fusion and cristae structures. The excitation wavelengths of TPE-Ph-In include 450 nm, 488 nm, and 489 nm, while its emission wavelengths include 551-661 nm, 660 nm, and 694 nm. TPE-Ph-In can be used for studies on mitochondrial dysfunction associated with early apoptosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
