95 Results for "

thiol labeling

" in MedChemExpress (MCE) Product Catalog:
Products (95)

95 Results for "thiol labeling" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-100041
CAS No.: 71418-44-5
Purity:  99.31%
Synonyms: Monobromobimane
Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols .
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5
5 Cited Publications
Cat. No.: HY-D0098
CAS No.: 75350-46-8
Synonyms: N-(5-Fluoresceinyl)maleimide
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
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3
3 Cited Publications
Cat. No.: HY-136769
CAS No.: 129179-83-5
Purity:  99.73%
Biotin-HPDP is a biochemical reagent. Biotin-HPDP can couple with GMPS and label free protein thiols. Biotin-HPDP can be used as a biological material or organic compound for life science related research .
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2
2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
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1
1 Cited Publications
Cat. No.: HY-138200
CAS No.: 1437796-65-0
Purity:  99.43%
Synonyms: Cyanine5 maleimide
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).
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1
1 Cited Publications
Cat. No.: HY-W011500S
CAS No.: 1174025-33-2
TCEP-d16 (hydrochloride) is the deuterium labeled TCEP hydrochloride . TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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1
1 Cited Publications
Cat. No.: HY-D0807
CAS No.: 63368-54-7
Synonyms: 5-Iodoacetamidofluorescein
5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains) .
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1
1 Cited Publications
Cat. No.: HY-D1605
CAS No.: 1180490-57-6
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm) .
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1
1 Cited Publications
Cat. No.: HY-N0394S1
CAS No.: 1192736-38-1
L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
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1
1 Cited Publications
Cat. No.: HY-D1261
CAS No.: 210292-65-2
Synonyms: thiol-green 1
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells . Ex: 488 nM; Em: 540 nM.
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1
1 Cited Publications
Cat. No.: HY-135235
CAS No.: 1947408-74-3
Purity:  98.14%
Target:  

Fluorescent Dye

Research Areas:  

Others

Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .
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1
1 Cited Publications
Cat. No.: HY-N0394S4
CAS No.: 2483736-13-4
L-Cystine-3,3'- 13C2 is the 13C labeled L-Cystine . L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes .
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Cat. No.: HY-D2906
CAS No.: 1825332-75-9
Alexa fluor 647 maleimide is a bright, far-red-emitting fluorescent dye for labeling of protein SH groups (Ex/Em = 656/670 nm). Alexa fluor 647 maleimide can be used to attach AF 647 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Alexa Fluor 647 maleimide is promising for research of cell biology, neuroscience, and disease diagnostics .
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Cat. No.: HY-123749
CAS No.: 114458-99-0
Purity:  86.61%
Synonyms: 5-TMRIA
Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues. Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) can be used to covalently label DNA fragments .
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Cat. No.: HY-W998680
CAS No.: 2228857-33-6
Synonyms: 5-FITC-Maleimide
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
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Cat. No.: HY-D1781
CAS No.: 2411398-95-1
NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis .
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Cat. No.: HY-D2381
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .
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Cat. No.: HY-D1390A
CAS No.: 2130955-10-9
Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
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Cat. No.: HY-130509
CAS No.: 81213-52-7
Synonyms: Otmpmms
Research Areas:  

Infection

MTSSL (Otmpmms) is a highly reactive thiol-specific spin label that can be used to label thiol residues in proteins for the determination of protein structure and dynamics, as well as studies on protein-protein interactions. MTSSL serves as a nitroxide labeling reagent for cysteine residues in recombinant mouse prion protein (moPrP C) mutants. MTSSL can be applied in studies of transmissible spongiform encephalopathies (prion diseases) .
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Cat. No.: HY-119493
CAS No.: 135980-66-4
Purity:  98.39%
Target:  

Fluorescent Dye

Research Areas:  

Others

MSBN is a highly selective fluorogenic probe for thiols. MSBN can be used to image thiols in live cells selectively and specifically label protein thiols with a signal to determine various reversible protein thiol modifications .
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