64 Results for "

thyroxine

" in MedChemExpress (MCE) Product Catalog:
Products (64)

64 Results for "thyroxine" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-18341
CAS No.: 51-48-9
Synonyms: Levothyroxine; T4
L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-18341B
CAS No.: 55-03-8
Synonyms: Levothyroxine sodium; T4 sodium
L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-18341A
CAS No.: 6106-07-6
Synonyms: Sodium levothyroxine pentahydrate
L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-W010669
CAS No.: 25416-65-3
Synonyms: Sodium levothyroxine
L-Thyroxine sodium xhydrate (Levothyroxine; T4) is a synthetic hormone in the treatment of hypothyroidism. DIO enzymes convert biologically active hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-101406
CAS No.: 77074-49-8
Purity:  99.84%
Synonyms: T4 Sulfate
Thyroxine sulfate is a thyroid hormone metabolite.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0035
CAS No.: 57-68-1
Synonyms: Sulfadimidine; Sulfadimerazine
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Neurological Disease

Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B0035A
CAS No.: 1981-58-4
Synonyms: Sulfadimidine sodium; Sulfadimerazine sodium
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Neurological Disease

Sulfamethazine (Sulfadimidine) sodium is a brain-penetrant sulfonamide antibiotic. Sulfamethazine sodium inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine sodium can be used for research on bacterial infections .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N1957
CAS No.: 31271-07-5
Synonyms: γ-Mangostin
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer . Gamma-Mangostin inhibits [3 H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W010696
CAS No.: 5817-39-0
Synonyms: 3′,5′,3-Triiodothyronine
Research Areas:  

Cardiovascular Disease

Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine . Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B0558
CAS No.: 22232-54-8
Target:  

p38 MAPK

Research Areas:  

Neurological Disease Endocrinology

Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D0896
CAS No.: 82-76-8
Synonyms: ANSA; 8-Anilino-1-naphthalenesulfonic acid
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (Ki=2.09×10 6 M -1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W008859
CAS No.: 67-30-1
Synonyms: Tetraiodothyroacetic acid; 3,3',5,5'-Tetraiodothyroacetic acid
Tetrac (Tetraiodothyroacetic acid), a derivative of L-thyroxine (T4), is a thyrointegrin receptor antagonist. Tetrac blocks the actions of T4 and 3,5,3'-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3. Tetra has anti-angiogenic and anti-tumor activities .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D0896A
CAS No.: 28836-03-5
Synonyms: NSC 1746 ammonium; Peri acid, phenyl- ammonium; Phenyl peri acid ammonium
ANS ammonium is a potent antibacterial agent and a textile dye. ANS ammonium can be used as fluorescence probe. ANS ammonium blocks the binding of triiodothyronine to thyroxine binding globulin in radioimmunoassay of triiodothyronine .
loading...
    loading...
Cat. No.: HY-107903
CAS No.: 9010-34-8
Purity:  93%
Synonyms: Thyroglobulin from bovine
Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .
loading...
    loading...
Cat. No.: HY-B1234
CAS No.: 5466-77-3
Synonyms: Octyl methoxycinnamate
Octinoxate (Octyl methoxycinnamate) is a thyroid hormone receptor agonist, reducing the levels of triiodothyronine (T3) and thyroxine (T4) and transcription levels of genes related to type II deiodinase (deio2) in Japanese Medaka. Octinoxate is commonly used as a safe ultraviolet (UV) filter used in the aquatic environment. Octinoxate inhibits CYP1A1 and CYP1B1 to regulate hyaluronan (HA) (HY-B0633A) metabolism in a PI3K pathway-dependent manner in human keratinocytes. Octinoxate also exhibits an anti-estrogenic and anti-androgenic effect in vitro and in vivo .
loading...
    loading...
Cat. No.: HY-18341R
CAS No.: 51-48-9
Synonyms: Levothyroxine (Standard); T4 (Standard)
L-Thyroxine (Standard) is the analytical standard of L-Thyroxine. This product is intended for research and analytical applications. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
loading...
    loading...
Cat. No.: HY-A0069
CAS No.: 562-10-7
Doxylamine succinate is a first-generation antihistamine and acts as a histamine H1 receptor antagonist. Doxylamine succinate is orally active, possessing analgesic and hypnotic activities. Doxylamine succinate enhances the activities of CYP2B, CYP2A, CYP3A and thyroxine-glucuronosyltransferase via promoting substrate hydroxylation and thyroxine metabolic pathways. Doxylamine succinate decreases serum thyroxine (T4) level and elevates serum thyroid-stimulating hormone (TSH) level. Doxylamine succinate induces liver enlargement and increases the activities of hepatic microsomal cytochrome P450, cytochrome b5 and NADPH-cytochrome c reductase. Doxylamine succinate can be used for the research of nausea, allergy, insomnia .
loading...
    loading...
Cat. No.: HY-18341S2
CAS No.: 720710-30-5
L-Thyroxine- 13C6 is the 13C labeled L-Thyroxine . L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
loading...
    loading...
Cat. No.: HY-A0152
CAS No.: 51-49-0
Synonyms: D-T4
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. D-Thyroxine can inhibit goiter, promote metamorphosis of tadpoles and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia .
loading...
    loading...
Cat. No.: HY-113082
CAS No.: 1596-67-4
Purity:  98.91%
L-Thyronine is a deiodinated thyroxine.
loading...
    loading...