22 Results for "

tobacco alkaloid

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "tobacco alkaloid" in MCE Product Catalog:

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3
3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
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2
2 Cited Publications
Cat. No.: HY-126047A
CAS No.: 2743-90-0
Purity:  98.75%
Research Areas:  

Inflammation/Immunology

(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
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1
1 Cited Publications
Cat. No.: HY-19918A
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
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Cat. No.: HY-B1532
CAS No.: 494-52-0
Synonyms: (S)-Anabasine; (+)-Anabasine
Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
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Cat. No.: HY-W001909
CAS No.: 532-12-7
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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Cat. No.: HY-118614
CAS No.: 487-19-4
Purity:  99.35%
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
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Cat. No.: HY-135560
CAS No.: 494-04-2
Purity:  99.92%
Synonyms: Nicotellin
Target:  

Cytochrome P450

Research Areas:  

Neurological Disease

Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .
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Cat. No.: HY-126047AR
CAS No.: 2743-90-0
(R,S)-Anatabine (Standard) is the analytical standard of (R,S)-Anatabine (HY-126047A). This product is intended for research and analytical applications. (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
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Cat. No.: HY-W001909S
CAS No.: 66148-17-2
Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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Cat. No.: HY-121255
CAS No.: 482-22-4
Purity:  ≥99.0%
Synonyms: (R)-Cryptopleurine; NSC 19912
Target:  

TMV

Research Areas:  

Cancer

(–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
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Cat. No.: HY-W004515
CAS No.: 6419-36-9
Research Areas:  

Others

3-Pyridineacetic acid hydrochloride is a high homolog of nicotinic acid and is a decomposition product of nicotine (and other tobacco alkaloids). 3-Pyridylacetic acid hydrochloride can be used to synthesize anti-inflammatory agents or as a precursor for the preparation of herbicides .
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Cat. No.: HY-N12249
CAS No.: 145987-74-2
7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .
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Cat. No.: HY-B1178R
CAS No.: 486-56-6
Synonyms: (-)-Cotinine (Standard); (S)-Cotinine (Standard); NIH-10498 (Standard)
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
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Cat. No.: HY-126047AS
CAS No.: 1020719-11-2
(R,S)-Anatabine-d4 is a deuterated labeled (R,S)-Anatabine (HY-126047A). (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
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Cat. No.: HY-W004515S
CAS No.: 1219802-37-5
3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride . 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
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Cat. No.: HY-W001909R
CAS No.: 532-12-7
Myosmine (Standard) is the analytical standard of Myosmine. This product is intended for research and analytical applications. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
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Cat. No.: HY-W004515R
CAS No.: 6419-36-9
3-Pyridylacetic acid (hydrochloride) (Standard) is the analytical standard of 3-Pyridylacetic acid (hydrochloride). This product is intended for research and analytical applications. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids). 3-Pyridylacetic acid hydrochloride can be used to synthesize anti-inflammatory agents or as a precursor for the preparation of herbicides .
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Cat. No.: HY-W014928
CAS No.: 53912-89-3
Synonyms: (S)-Anabasine hydrochloride; (+)-Anabasine hydrochloride
Target:  

nAChR

Research Areas:  

Neurological Disease

Anabasine ((S)-Anabasine) hydrochloride is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 µM) .
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Cat. No.: HY-B1532R
CAS No.: 494-52-0
Synonyms: (S)-Anabasine (Standard); (+)-Anabasine (Standard)
Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
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Cat. No.: HY-126047S
(R,S)-Anatabine-d4 hydrochloride is the deuterium labeled (R,S)-Anatabine hydrochloride (HY-126047A). (R,S)-Anatabine is a a minor tobacco alkaloid found in the?Solanaceae?family of?plants?that can be used as a specific marker for the detection of tobacco use.
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