648 Results for "

utilization

" in MedChemExpress (MCE) Product Catalog:
Products (648)

648 Results for "utilization" in MCE Product Catalog:

50
DPPH
DPPH
0 Images
50 Publications Verification
Cat. No.: HY-112053
CAS No.: 1898-66-4
Purity:  98.77%
Synonyms: 2,2-Diphenyl-1-picrylhydrazyl
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Metabolic Disease

DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
40
Exendin(9-39) amide acetate
Exendin(9-39) amide acetate
0 Images
40 Cited Publications
Cat. No.: HY-P0264A
CAS No.: 2051593-46-3
Synonyms: Avexitide acetate
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Exendin(9-39) amide (Avexitide) acetate is a glucagon-like peptide-1 (GLP-1) antagonist that competes with endogenous GLP-1 for the GLP-1R, counteracting the effects of excessive GLP-1 secretion. Exendin(9-39) amide acetate can be utilized in Postbariatric hypoglycemia (PBH) research .
19
C12-200
C12-200
0 Images
19 Cited Publications
Cat. No.: HY-145405
CAS No.: 1220890-25-4
Purity:  99.91%
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
10
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
0 Images
10 Cited Publications
Cat. No.: HY-W074143
CAS No.: 36309-88-3
Synonyms: [Ru(DPP)3]Cl2
Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
9
ROS Assay Kit
ROS Assay Kit
0 Images
9 Cited Publications
Cat. No.: HY-K0320

MCE ROS Assay Kit utilizes the fluorescent probe DCFH-DA to detect ROS.

8
Molidustat
Molidustat
0 Images
8 Cited Publications
Cat. No.: HY-12654
CAS No.: 1154028-82-6
Purity:  98.58%
Synonyms: BAY 85-3934
Target:  

HIF/HIF Prolyl-Hydroxylase

Research Areas:  

Cardiovascular Disease

Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia .
6
Cell Ferrous Iron (Fe2+) Assay Kit (Fluorometric)
Cell Ferrous Iron (Fe2+) Assay Kit (Fluorometric)
0 Images
6 Cited Publications
Cat. No.: HY-K0322

MCE Cell Ferrous Iron (Fe2+) Assay Kit (Fluorometric) utilizes fluorescence detection technology to analyze the levels of ferrous ions (Fe2+) in cells.

6
Urea
Urea
0 Images
6 Cited Publications
Cat. No.: HY-Y0271
CAS No.: 57-13-6
Synonyms: Carbonyl diamide
Category:  

Natural Products Microorganisms Endogenous metabolite Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Target:  

Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK

Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
6
MB05032
MB05032
0 Images
6 Cited Publications
Cat. No.: HY-16307
CAS No.: 261365-11-1
Target:  

FBPase

Research Areas:  

Metabolic Disease Cancer

MB05032 is a fructose-1,6-bisphosphatase (FBP1/FBPase) inhibitor with an IC50 value of 16 nM. MB05032 blocks FBP1-mediated glycolysis inhibition in NK cells, restores NK cell glucose uptake, lactate production, degranulation, perforin production, and cytotoxicity against gastric cancer cells. MB05032 elevates ATP/ADP ratios, increases glucose utilization, and enhances insulin secretion in pancreatic β-cells. MB05032 increases neutrophil adhesion, phagocytosis, and mRNA abundance of HKII, ITGA9, CD36 in subclinically hypocalcemic dairy cows. MB05032 inhibits gluconeogenesis in hepatocytes, acts as the active metabolite of prodrug Managlinat dialanetil (MB06322) (HY-14955). MB05032 can be used for the research of gastric cancer, type 2 diabetes, subclinical hypocalcemia, and insulin resistance .
5
Xylose
Xylose
0 Images
5 Cited Publications
Cat. No.: HY-N0537
CAS No.: 58-86-6
Synonyms: D-(+)-Xylose; (+)-Xylose; Wood sugar
Category:  

Other Diseases Endogenous metabolite Disease Research Fields Saccharides Monosaccharides

Target:  

Environmental Pollutants Endogenous Metabolite

Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .
5
Concanavalin A
Concanavalin A
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5 Cited Publications
Cat. No.: HY-P2149
CAS No.: 11028-71-0
Concanavalin A can be coupled to agarose to form Concanavalin A (agarose) (HY-P2149A). Concanavalin A (ConA) is a selective, competitive binding agent that targets specific carbohydrate structures containing glucose and mannose; it acts as a mitogen and exhibits varying degrees of cytotoxicity, hepatotoxicity, and teratogenicity. Concanavalin A is also utilized for in vivo blood glucose monitoring in the context of diabetes .
4
Mycoplasma Detection Kit (PCR)
Mycoplasma Detection Kit (PCR)
0 Images
4 Cited Publications
Cat. No.: HY-K0552

MCE Mycoplasma Detection Kit (PCR) is a diagnostic kit that utilizes the PCR method to detect mycoplasma contamination in biological materials such as cultured cells.

4
Rat IgG2a kappa, Isotype Control
Rat IgG2a kappa, Isotype Control
0 Images
4 Cited Publications
Cat. No.: HY-P990679

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .
3
HPPE
HPPE
0 Images
3 Cited Publications
Cat. No.: HY-153040
CAS No.: 1325721-55-8
Purity:  99.67%
Synonyms: Bach1-IN-1
Target:  

Mitochondrial Metabolism

Research Areas:  

Metabolic Disease

HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD .
3
DODAP
DODAP
0 Images
3 Cited Publications
Cat. No.: HY-130751
CAS No.: 127512-29-2
Purity:  ≥98.0%
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
3
Diethyl succinate
Diethyl succinate
0 Images
3 Cited Publications
Cat. No.: HY-Y0836
CAS No.: 123-25-1
Synonyms: Diethyl Butanedioate
Category:  

Natural Products other families Metabolic Disease Plants Disease Research Fields

Target:  

Environmental Pollutants Biochemical Assay Reagents Reactive Oxygen Species (ROS)

Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
3
DSPE-PEG2000-Maleimide sodium (purity>95%)
DSPE-PEG2000-Maleimide sodium (purity>95%)
0 Images
3 Cited Publications
Cat. No.: HY-140739
Purity:  99.58%
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
2
α-Terpineol
α-Terpineol
0 Images
2 Cited Publications
Cat. No.: HY-N5142
CAS No.: 98-55-5
Category:  

Infection Other Monoterpenes Saururaceae Terpenoids Myrtaceae Plants Eucalyptus globulus Labill. Disease Research Fields Inflammation/Immunology

Target:  

Environmental Pollutants Antibiotic Bacterial Fungal AMPK NF-κB

α-Terpineol (with oral activity) can be found in Eucalyptus globulus Labill. α-Terpineol exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria.α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. In addition, α-Terpineol exhibits antineuropathic and anti-inflammatory activities. α-Terpineol can be utilized in research related to diarrhea, neuropathic pain, infections, and inflammation .
2
TRITC-dextran, MW 4000
TRITC-dextran, MW 4000
0 Images
2 Cited Publications
Cat. No.: HY-158082
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 4000
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
1
MitoTracker Orange CMTMRos
MitoTracker Orange CMTMRos
0 Images
1 Cited Publications
Cat. No.: HY-D1696
CAS No.: 199116-50-2
MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm) .
Assay Types