1. JAK/STAT Signaling Stem Cell/Wnt
  2. STAT
  3. STAT6-IN-1

STAT6-IN-1 (compound 19a) is a STAT6 inhibitor with a high affinity for the SH2 domain of STAT6 (IC50=0.028 µM). STAT6-IN-1 can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer.

For research use only. We do not sell to patients.

STAT6-IN-1 Chemical Structure

STAT6-IN-1 Chemical Structure

CAS No. : 1637532-68-3

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Description

STAT6-IN-1 (compound 19a) is a STAT6 inhibitor with a high affinity for the SH2 domain of STAT6 (IC50=0.028 µM). STAT6-IN-1 can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1][2].

IC50 & Target

IC50: 0.028 µM (SH2)[1].

Molecular Weight

745.54

Formula

C33H37IN3O7P

CAS No.
SMILES

O=C([C@H]1N(CCC1)C([C@H](C(C)(C)C)NC(/C=C(C2=CC=C(C=C2)OP(O)(O)=O)\C)=O)=O)N(C3=CC=CC=C3)C4=CC=C(C=C4)I

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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STAT6-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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STAT6-IN-1
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HY-148096
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