STAT6-IN-7
Based on 1 Customer Validation
STAT6-IN-7 is a STAT6 inhibitor. STAT6-IN-7 exhibits an IC50 of 0.28 μM for inhibiting the binding of human STAT6/pIL-4Rα. STAT6-IN-7 can be used in the research of atopic dermatitis.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 3033743-58-4
- Formula: C36H33F3N8O4
- Molecular Weight:698.69
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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STAT6 |
IL-4 |
STAT6-IN-7 (Compound 178) is a STAT6 inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3033743-58-4
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Appearance Solid
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Molecular Weight 698.69
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Formula C36H33F3N8O4
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Color White to off-white
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SMILES
O=C(C1=CC(NC(C2=CC(C(F)(F)F)=CC3=C2N(CCOC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1)NC6=NN(C7CC7)C=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (143.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4312 mL | 7.1562 mL | 14.3125 mL | 35.7812 mL |
| 5 mM | 0.2862 mL | 1.4312 mL | 2.8625 mL | 7.1562 mL | |
| 10 mM | 0.1431 mL | 0.7156 mL | 1.4312 mL | 3.5781 mL | |
| 15 mM | 0.0954 mL | 0.4771 mL | 0.9542 mL | 2.3854 mL | |
| 20 mM | 0.0716 mL | 0.3578 mL | 0.7156 mL | 1.7891 mL | |
| 25 mM | 0.0572 mL | 0.2862 mL | 0.5725 mL | 1.4312 mL | |
| 30 mM | 0.0477 mL | 0.2385 mL | 0.4771 mL | 1.1927 mL | |
| 40 mM | 0.0358 mL | 0.1789 mL | 0.3578 mL | 0.8945 mL | |
| 50 mM | 0.0286 mL | 0.1431 mL | 0.2862 mL | 0.7156 mL | |
| 60 mM | 0.0239 mL | 0.1193 mL | 0.2385 mL | 0.5964 mL | |
| 80 mM | 0.0179 mL | 0.0895 mL | 0.1789 mL | 0.4473 mL | |
| 100 mM | 0.0143 mL | 0.0716 mL | 0.1431 mL | 0.3578 mL |
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