Tebufelone
Based on 1 Customer Validation
Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 112018-00-5
- Formula: C20H28O2
- Molecular Weight:300.44
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
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COX-2 |
5-LO |
Chemical Information
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CAS No. 112018-00-5
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Appearance Solid
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Molecular Weight 300.44
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Formula C20H28O2
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Color White to off-white
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SMILES
OC1=C(C=C(C(CCCC#C)=O)C=C1C(C)(C)C)C(C)(C)C
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Synonyms
NE-11740
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. [Content Brief]
[2]. Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)