1. PROTAC
  2. Ligand for E3 Ligase
  3. Thalidomide-5,6-F

Thalidomide-5,6-F 

Cat. No.: HY-W093272
Handling Instructions

Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-F can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-5,6-F Chemical Structure

Thalidomide-5,6-F Chemical Structure

CAS No. : 1496997-41-1

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Estimated Time of Arrival: December 31
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Description

Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-F can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target[1]

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

294.21

Formula

C₁₃H₈F₂N₂O₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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Product Name:
Thalidomide-5,6-F
Cat. No.:
HY-W093272
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