1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. Thermopsoside

Thermopsoside 

Cat. No.: HY-N6023
Handling Instructions

Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively.

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Thermopsoside Chemical Structure

Thermopsoside Chemical Structure

CAS No. : 19993-32-9

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Description

Thermopsoside is a flavone derivative isolated from Aspalathus linearis. Thermopsoside exhibits inhibitory effects on CYP450 isozymes with IC50 values of 6.0 μM, 9.5 μM, 12.0 μM, 32.0 μM, for CYP3A4, CYP2C19, CYP2D6 and CYP2C9, respectively[1].

Molecular Weight

462.40

Formula

C₂₂H₂₂O₁₁

CAS No.

19993-32-9

SMILES

O=C1C2=C(O)C=C(O[[email protected]@H]3O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]3O)CO)C=C2OC(C4=CC(OC)=C(O)C=C4)=C1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

ThermopsosideCytochrome P450CYPsInhibitorinhibitorinhibit

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