Tovecimig
Based on 1 Customer Validation
HY-P991033 is an VEGFA/DLL4-targeting G1-scFvlh_L-κ type bispecific antibody.
For research use only. We do not sell to patients.
- Purity: 97.39%
- CAS No.: 2923284-73-3
- Molecular Weight:199.624 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
More
Biological Activity
IgG1-kappa-[scFv]2-lambda-heavy
Human
VEGFA & DLL4
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
IgG1-kappa-[scFv]2-lambda-heavy
ELISA, FACS, Functional assay
-
Immobilized VEGF121 Protein, Human (120 a.a, HY-P7420) can bind Tovecimig. The EC50 for this effect is 10.9 ng/mL. -
Immobilized Delta-like protein 4/DLL4 Protein, Human (HEK293, HY-P72972) can bind Tovecimig. The EC50 for this effect is 16.06 ng/mL. -
Flow cytometric analysis of 1X106 HeLa cells with Tovecimig (HY-P991033, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
Chemical Information
-
CAS No. 2923284-73-3
-
Appearance Liquid
-
Molecular Weight 199.624 kDa
-
Color Colorless to light yellow
-
SMILES
[Tovecimig]
-
Synonyms
CTX-009
-
Shipping
Shipping with dry ice.
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (254 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)