Triacetylresveratrol
Based on 1 publication(s) in Google Scholar
Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects.
For research use only. We do not sell to patients.
- Purity: 99.11%
- CAS No.: 42206-94-0
- Formula: C20H18O6
- Molecular Weight:354.35
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Publications Citing Use of MedChemExpress (MCE) Triacetylresveratrol
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Biological Activity
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NF-κB |
STAT3 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
7.5 μM
Compound: 18
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Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level
Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level
|
[PMID: 26750258] |
| HEK293 | IC50 |
>10 μM
Compound: 18
|
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
|
[PMID: 26750258] |
| HEK293 | IC50 |
11.8 μM
Compound: 18
|
Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced increase of intracellular calcium level
|
[PMID: 26750258] |
| HeLa | IC50 |
3.4 μM
Compound: 92
|
Anticancer activity against human HeLa cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
Anticancer activity against human HeLa cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
|
[PMID: 32485531] |
Triacetylresveratrol significantly down-regulates anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability, and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 42206-94-0
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Appearance Solid
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Molecular Weight 354.35
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Formula C20H18O6
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Color White to off-white
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SMILES
O=C(OC1=CC=C(/C=C/C2=CC(OC(C)=O)=CC(OC(C)=O)=C2)C=C1)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
Resveratrol Analog ResA1 Targeting MoYpk1 Exhibits Broad-Spectrum Antifungal Activity against Rice Blast. [Abstract]2026 Jun 3;74(21):16299-16311. PMID: 42172023
Solvent & Solubility
DMSO : 125 mg/mL (352.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (560 KB)
- English - EN (560 KB)
- Français - FR (560 KB)
- Deutsch - DE (560 KB)
- Norwegian - NO (560 KB)
- Español - ES (560 KB)
- Swedish - SV (560 KB)
- Italian - IT (560 KB)
- Korean - KR (560 KB)
- Portuguese - PT (560 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8221 mL | 14.1103 mL | 28.2207 mL | 70.5517 mL |
| 5 mM | 0.5644 mL | 2.8221 mL | 5.6441 mL | 14.1103 mL | |
| 10 mM | 0.2822 mL | 1.4110 mL | 2.8221 mL | 7.0552 mL | |
| 15 mM | 0.1881 mL | 0.9407 mL | 1.8814 mL | 4.7034 mL | |
| 20 mM | 0.1411 mL | 0.7055 mL | 1.4110 mL | 3.5276 mL | |
| 25 mM | 0.1129 mL | 0.5644 mL | 1.1288 mL | 2.8221 mL | |
| 30 mM | 0.0941 mL | 0.4703 mL | 0.9407 mL | 2.3517 mL | |
| 40 mM | 0.0706 mL | 0.3528 mL | 0.7055 mL | 1.7638 mL | |
| 50 mM | 0.0564 mL | 0.2822 mL | 0.5644 mL | 1.4110 mL | |
| 60 mM | 0.0470 mL | 0.2352 mL | 0.4703 mL | 1.1759 mL | |
| 80 mM | 0.0353 mL | 0.1764 mL | 0.3528 mL | 0.8819 mL | |
| 100 mM | 0.0282 mL | 0.1411 mL | 0.2822 mL | 0.7055 mL |