VER-3323
VER-3323 is an oral active 5-HT2C agonist and belongs to the class of indoline analogs. VER-3323 reduces food intake in rats by inducing swallowing dysfunction, with no significant impact on energy expenditure generated through thermogenesis or exercise. VER-3323 can be utilized in obesity research.
For research use only. We do not sell to patients.
- CAS No.: 259857-99-3
- Formula: C11H15BrN2
- Molecular Weight:255.15
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
More
Biological Activity
|
5-HT2C Receptor |
Human 5-HT2C Receptor |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
11 nM
Compound: 49 (VER-3323)
|
Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate reader
Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate reader
|
[PMID: 15081042] |
| CHO | EC50 |
44 nM
Compound: 49 (VER-3323)
|
Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate reader
Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate reader
|
[PMID: 15081042] |
| CHO | EC50 |
719 nM
Compound: 49 (VER-3323)
|
Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometric imaging plate reader
Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometric imaging plate reader
|
[PMID: 15081042] |
Chemical Information
-
CAS No. 259857-99-3
-
Molecular Weight 255.15
-
Formula C11H15BrN2
-
SMILES
C[C@H](N)CN1C2=CC(Br)=CC=C2CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)