2-Nonylimidazole
2-Nonylimidazole is a CYP2A13 inhibitor with an IC50 of 277 μM. 2-Nonylimidazole modulates the enzymatic activity of CYP2A13. 2-Nonylimidazole is applicable to research on drug metabolism and tobacco-related cancers.
For research use only. We do not sell to patients.
- CAS No.: 52819-56-4
- Formula: C12H22N2
- Molecular Weight:194.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
CYP2A13 277 μM (IC50) |
In Vitro
2-Nonylimidazole (10 min pre-incubation, 60 min reaction) does not inhibit CYP2A6 from baculovirus-infected insect cell microsomes[1].
2-Nonylimidazole (10 min pre-incubation, 60 min reaction) inhibits CYP2A13 from Sf9 insect cell microsomes with an IC50 of 277 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 52819-56-4
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Molecular Weight 194.32
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Formula C12H22N2
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SMILES
CCCCCCCCCC1=NC=CN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)