Irindalone
Irindalone is a novel serotonin 5-HT2 antagonist.
For research use only. We do not sell to patients.
- CAS No.: 96478-43-2
- Formula: C24H29FN4O
- Molecular Weight:408.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT2 Receptor |
Irindalone causes a concentration-related inhibition of serotonin-induced contractions and shifts the serotonin curve to the right. Irindalone is more potent in inhibiting the serotonin-induced contractions. Irindalone has a similar profile in vitro, with a high affinity for serotonin 5-HT2 receptors and about a 10 times lower affinity for α1-adrenoceptors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 96478-43-2
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Molecular Weight 408.51
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Formula C24H29FN4O
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SMILES
O=C1NCCN1CCN2CCN([C@@H]3C[C@@H](C4=CC=C(F)C=C4)C5=C3C=CC=C5)CC2
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Synonyms
Lu 21-098
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)