- Signaling Pathways
- Anti-infection
- Antibiotic
Antibiotic
Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.
Antibiotic Isoform Specific Products
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Antibiotic
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Aminoglycoside
(46)
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Glycopeptide
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Lipopeptide
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Macrolide
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Oxazolidinone
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Quinolone
(101)
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Tetracycline
(42)
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β-lactam
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Antibiotic Related Products (3548)
Related Products (3548)
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Related Compound Screening Libraries (1)
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Antibiotic Isoform Comparison
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Pyrrolomycin B
0 ImagesCat. No.: HY-N14575CAS No.: 79763-00-1Pyrrolomycin B is a pyrrole antibiotic. Pyrrolomycin B has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-individual fungi activity. -
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LB 11058
0 ImagesCat. No.: HY-183459CAS No.: 591207-81-7LB 11058 is a Cephalosporin Antibacterial agent. LB 11058 inhibits the growth of pathogenic bacteria, including multidrug-resistant staphylococci and streptococci, but shows weak activity against Enterococcus faecium, Corynebacterium species, Enterobacteriaceae and non-fermenting Gram-negative bacilli. LB 11058 can be used in bacterial infection research. -
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Doxycycline fosfatex
0 ImagesCat. No.: HY-N0565DCAS No.: 83038-87-3Doxycycline fosfatex is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline fosfatex is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and fosfatex atoms. Doxycycline fosfatex also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline fosfatex induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline fosfatex also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline fosfatex has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers. -
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Anti-MRSA agent 12
0 ImagesCat. No.: HY-161803CAS No.: 2314380-76-0Anti-MRSA agent 12 (Compound SM-5) is an antibiotic, which exhibits antibacterial activity against Staphylococcus aureus, S. epidermidis and Escherichia coli with MIC of 7.81, 7.81 and 62.5 μM. Anti-MRSA agent 12 inhibits the methicillin-resistant S. aureus (MRSA) through inhibition of biofilm formation. -
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Indometacin-d7
0 ImagesCat. No.: HY-14397S2Indometacin-d7 is deuterated labeled Indomethacin (HY-14397). Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research. -
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Azidocillin sodium
0 ImagesCat. No.: HY-B2091ACAS No.: 35334-12-4Azidocillin sodium, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin sodium bears an azide functionality and retains on-target activity within bacteria. Azidocillin sodium can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases. Azidocillin sodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. -
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Oxytetracycline-13C,d3 hydrochloride
0 ImagesCat. No.: HY-W755036Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity. -
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Sulopenem etzadroxil (Standard)
0 ImagesCat. No.: HY-109754RCAS No.: 1000296-70-7Synonyms: PF-03709270 (Standard)Sulopenem etzadroxil (Standard) is the analytical standard of Sulopenem etzadroxil (HY-109754). This product is intended for research and analytical applications. Sulopenem etzadroxil is an orally active prodrug of the antibiotic Sulopenem (HY-105284). Sulopenem etzadroxil is active in mice infected with Bacillus anthracis. -
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Nafcillin sodium monohydrate (Standard)
0 ImagesCat. No.: HY-B0555ARCAS No.: 7177-50-6Nafcillin (sodium monohydrate) (Standard) is the analytical standard of Nafcillin (sodium monohydrate). This product is intended for research and analytical applications. Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections. -
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Isoplumbagin
0 ImagesCat. No.: HY-W452285CAS No.: 14777-17-4Isoplumbagin is antimicrobial agent. Isoplumbagin exhibits anticancer activity mainly through modulating mitochondrial dynamics and function. -
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Ala0-Actagardine
0 ImagesCat. No.: HY-N5203CAS No.: 223465-14-3Ala0-Actagardine is a lantibiotic found in the cultures of Actinoplanes liguriae ATCC 31048. -
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Lankacidinol A
0 ImagesCat. No.: HY-125618CAS No.: 23498-36-4Synonyms: T-2636 DLankacidinol A (T-2636 D) is an antibiotic, and shows antibacterial activity against Gram-positive bacteria. -
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Tebipenem (Standard)
0 ImagesSynonyms: LJC 11036 (Standard)Tebipenem (Standard) is the analytical standard of Tebipenem. This product is intended for research and analytical applications. Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. -
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Nothramicin
0 ImagesCat. No.: HY-165483CAS No.: 205752-47-2Nothramicin is an anthracycline antibiotic with anti-mycobacterial activity . -
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Arylomycin A3
0 ImagesCat. No.: HY-N13956CAS No.: 459844-21-4Arylomycin A3 is a lipohexapeptide antibiotic against Gram-positive bacteria. -
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Lenapenem hydrochloride hydrate
0 ImagesCat. No.: HY-105180ACAS No.: 149882-71-3Synonyms: BO-2727 hydrochloride hydrateLenapenem (BO-2727) hydrochloride hydrate, a carbapenem antibiotic, has potent antibacterial activity against Gram-positive and Gram-negative bacteria including P. aeruginosa. -
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Basacv
0 ImagesCat. No.: HY-136991CAS No.: 95676-71-4Basacv is a DNA-polyintercalating bifunctional compound with DNA-high affinity. Basacv is structurally analogous to the antibiotic anti-tumour drug Triostin A and act as a bis-intercalator. -
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Tedizolid-13C,d3
0 ImagesCat. No.: HY-14855SCAS No.: 2931763-72-1Synonyms: TR 700-13C,d3; Torezolid-13C,d3; DA-7157-13C,d3Tedizolid-13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome. -
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Ampicillin trihydrate (Standard)
0 ImagesCat. No.: HY-B0522BRCAS No.: 7177-48-2Synonyms: D-(-)-α-Aminobenzylpenicillin trihydrate (Standard)Ampicillin (trihydrate) (Standard) is the analytical standard of Ampicillin (trihydrate). This product is intended for research and analytical applications. Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. -
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Ciprofloxacin-d4
0 ImagesCat. No.: HY-B0356S2Synonyms: Bay-09867-d4Ciprofloxacin-d4 (Bay-09867-d4) is deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. -
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Sorry. There is currently no product that acts on isoform Bcl-2, Bcl-W and Bim together.Please
try each isoform separately.