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Ertapenem
0 ImagesCat. No.: HY-A0294CAS No.: 153832-46-3Synonyms: MK-0826Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract. -
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Bafilomycin A1 (Standard)
0 ImagesCat. No.: HY-100558RCAS No.: 88899-55-2Synonyms: BafA1 (Standard)Bafilomycin A1 (Standard) is the analytical standard of Bafilomycin A1 (HY-100558). This product is intended for research and analytical applications. Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis. -
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Tacrolimus-d3
0 ImagesCat. No.: HY-13756S2Synonyms: FK506-d3; Fujimycin-d3; FR900506-d3Tacrolimus-d3 (FK506-d3) is the deuterated-labeled Tacrolimus (HY-13756). Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. -
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Capreomycin
0 ImagesCat. No.: HY-P3270CAS No.: 11003-38-6Capreomycin is a macrocyclic peptide antibiotic. Capreomycin can be used for anti-multidrug-resistant-tuberculosis research. Capreomycin can inhibit phenylalanine synthesis in in mycobacterial ribosomes translation -
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Minocycline-d7
0 ImagesCat. No.: HY-W654013Minocycline-d7 is deuterium labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect. -
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Cefazolin-13C2,15N
0 ImagesSynonyms: Cephazolin-13C2,15NCefazolin-13C2,15N (Cephazolin-13C2,15N) is 13C and 15N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD). -
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Rosuvastatin (Standard)
0 ImagesCat. No.: HY-17504ARCAS No.: 287714-41-4Synonyms: ZD 4522 (Standard)Rosuvastatin (Standard) is the analytical standard of Rosuvastatin (HY-17504A). This product is intended for research and analytical applications. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels. -
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Pyocyanin (Standard)
0 ImagesCat. No.: HY-111278RCAS No.: 85-66-5Synonyms: Pyocyanine (Standard); Sanazin (Standard); Sanasin (Standard)Pyocyanin (Standard) is the analytical standard of Pyocyanin. This product is intended for research and analytical applications. Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity[1][2][3][4]. -
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2-ambo-Vitamin E-13C6
0 ImagesCat. No.: HY-N0683SCAS No.: 2140857-08-3Synonyms: 2-ambo-α-Tocopherol-13C6α-Vitamin E-13C6 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant. -
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Cefcapene pivoxil
0 ImagesCat. No.: HY-135221ACAS No.: 105889-45-0Cefcapene pivoxil, the pivalate ester prodrug form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene has the potential for the palmoplantar pustulosis (PPP) research. -
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- Indolicidin TFA
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Fluconazole mesylate
0 ImagesCat. No.: HY-B0101BCAS No.: 159532-41-9Synonyms: UK 49858 mesylateFluconazole (UK-49858) mesylate is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole mesylate inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL. -
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Caryophyllene oxide (Standard)
0 ImagesCaryophyllene oxide (Standard) ((-)-Caryophyllene oxide (Standard)) is the analytical standard of Caryophyllene oxide (HY-N3544). This product is intended for research and analytical applications. Caryophyllene oxide is a bicyclic sesquiterpene with anticancer effects. Caryophyllene oxide induces apoptosis of PC-3 cells. Caryophyllene oxide shows analgesic and anti-inflammatory activities. Caryophyllene oxide has insecticidal, antioxidant, antimicrobial, antifungal, and antiparasitic properties. -
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RhlR antagonist 1
0 ImagesCat. No.: HY-131337CAS No.: 2614320-29-3RhlR antagonist 1 is a potent RhlR antagonist with an IC50 of 26 μM. RhlR antagonist 1 displays selective RhlR antagonism over LasR and PqsR, strong inhibition of biofilm formation in static and dynamic settings, and reduces production of virulence factors such as rhamnolipid and pyocyanin in P. aeruginosa. RhlR antagonist 1 can be utilized for developing QS-modulating molecules in the control of P. aeruginosa infections. RhlR antagonist 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. -
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Evybactin
0 ImagesCat. No.: HY-P3473Evybactin is a DNA gyrase inhibitor. Evybactin is a selective inhibitor of Mycobacterium tuberculosis with a MIC value of 0.25 µg/mL. Evybactin is the first antimicrobial compound found to employ this unusual mechanism of selectivity. -
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Vitamin D3-13C5
0 ImagesCat. No.: HY-15398S4CAS No.: 2483734-99-0Synonyms: Cholecalciferol-13C5; Colecalciferol-13C5Vitamin D3-13C5 is the 13C-labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. -
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L-Lactic acid-2-13C1
0 ImagesCat. No.: HY-Y0479S3CAS No.: 740788-63-0Synonyms: (S)-2-Hydroxypropanoic acid-13C1L-Lactic acid-2-13C1 is the 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. -
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Afabicin disodium
0 ImagesCat. No.: HY-109000ACAS No.: 1518800-29-7Synonyms: Debio 1450 disodium; AFN-1720 disodiumAfabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. -
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Contezolid acefosamil
0 ImagesCat. No.: HY-19915ACAS No.: 1807497-11-5Synonyms: MRX-4Contezolid acefosamil (MRX-4) is the orally active proagent of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA. -
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Voxvoganan
0 ImagesCat. No.: HY-119123CAS No.: 1166254-80-3Synonyms: LTX-109 -
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