1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N12866
    Monensin C
    Inhibitor
    Monensin C is an oxygen-containing heterocyclic polyether antibiotic. Monensin C has antibacterial, mycobacterial, fungal and protozoan activity, but it has a weaker effect on Gram-negative bacteria and has an inhibitory effect on HeLa cells.
    Monensin C
  • HY-152105
    Metallo-β-lactamase-IN-9
    Inhibitor
    Metallo-β-lactamase-IN-9 (Compound 23) is a pan metallo-beta-lactamase (MBL) inhibitor with IC50s of 35, 269 and 369 nM against NDM-1, VIM-1 and IMP-1, respectively.
    Metallo-β-lactamase-IN-9
  • HY-N14505
    Mycinamicin Ⅵ
    Inhibitor
    Mycinamicin VI is a macrolide antibiotic. Mycinamicin VI shows activity against Gram-positive bacteria.
    Mycinamicin Ⅵ
  • HY-N5189
    Emerimicin IV
    Inhibitor
    Emerimicin IV mainly has activity against Gram-positive bacteria.
    Emerimicin IV
  • HY-129691
    Ro 14-1761
    Inhibitor
    Ro 14-1761 is a third-generation cephalosporin with antibacterial activity.
    Ro 14-1761
  • HY-N2984
    Calanolide E
    Inhibitor
    Calanolide E is a natural coumarin with weakly inhibitory towards the Bacilli strains with MIC values ranging from 0.25-0.50 mg/mL.
    Calanolide E
  • HY-180812
    Antibacterial agent 312
    Inhibitor
    Antibacterial agent 312 (Compound 8c) is a highly effective antibacterial agent that can effectively damage the integrity of bacterial membranes and enhance membrane permeability. Antibacterial agent 312 exhibits MIC values against Vibrio parahaemolyticus and Vibrio alginolyticus of 6 and 16 μg/mL respectively. Antibacterial agent 312 has bactericidal activity against Vibrio parahaemolyticus and can effectively inhibit the formation of biofilms. Antibacterial agent 312 demonstrates excellent biological safety and can be used for research on the infection of the aquatic pathogen Vibrio parahaemolyticus.
    Antibacterial agent 312
  • HY-N14722
    Lactonamycin
    Inhibitor
    Lactonamycin had strong activity against Gram-positive bacteria including Staphylococcus, Streptococcus, Enterococcus, MRSA (MIC of 0.39-0.78 μg/mL) and VRE (MIC of 0.39-0.78 μg/mL). Lactonamycin also has inhibitory effect on L-1210, P388, S180, FS-3, Ehrlich, B16-BL5 and other tumor cell lines (IC50s of 0.06-3.3 μg/mL).
    Lactonamycin
  • HY-N6680R
    Virginiamycin S1 (Standard)
    Inhibitor
    Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections.
    Virginiamycin S1 (Standard)
  • HY-129347
    Lankacyclinol A
    Inhibitor
    Lankacyclinol A is an orally active antibiotic isolated from Streptomyces rochei. Lankacyclinol A has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. Lankacyclinol A exhibits low toxicity in mice.
    Lankacyclinol A
  • HY-124106
    Resorstatin
    Inhibitor
    Resorstatin is a dialkylresorcinol that can be isolated from a liquid culture of Pseudomonas sp. Ki19. Resorstatin exhibits antimicrobial activity.
    Resorstatin
  • HY-179376
    Anti-virulence factor-IN-3
    Inhibitor
    Anti-virulence factor-IN-3 (Compound 21) is a covalent β-aminosulfinyl type anthrax edema factor (EF) inhibitor, with a Ki value of 0.44 μM. Anti-virulence factor-IN-3 generates an active ethylene sulfinyl intermediate, which forms an irreversible covalent bond with the Lys residue at the active center of EF, permanently inhibiting the adenylate cyclase activity of EF. Anti-virulence factor-IN-3 effectively inhibits the cAMP production induced by EF, with an EC50 value of 0.15 μM. Anti-virulence factor-IN-3 can be used for research on anthrax Infection.
    Anti-virulence factor-IN-3
  • HY-N2552R
    Vitamin K5 hydrochloride (Standard)
    Inhibitor
    Vitamin K5 (hydrochloride) (Standard) is the analytical standard of Vitamin K5 (hydrochloride). This product is intended for research and analytical applications. Vitamin K5 hydrochloride is a photosensitizer and a antimicrobial agent. Vitamin K5 hydrochloride is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 hydrochloride induces apoptosis of colon 26 cells. Vitamin K5 hydrochloride can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages[1][2][3].
    Vitamin K5 hydrochloride (Standard)
  • HY-A0208R
    Rosoxacin (Standard)
    Inhibitor
    Rosoxacin (Standard) is the analytical standard of Rosoxacin. This product is intended for research and analytical applications. Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 μg/mL).Rosoxacin can be used in studies of urinary tract infections and certain sexually transmitted diseases.
    Rosoxacin (Standard)
  • HY-W739149
    Rifapentine-d8
    Inhibitor
    Rifapentine-d8 is deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic used in tuberculosis research.
    Rifapentine-d<sub>8</sub>
  • HY-182310
    Antibacterial agent 333
    Inhibitor
    Antibacterial agent 333, Tryptanthrin (HY-N6607) derivative, is a antibacterial agent with antibacterial activity against Vibrio parahaemolyticus (MIC50 = 8 μg/mL) and Vibrio alginolyticus (MIC50 = 16 μg/mL). Antibacterial agent 333 inhibits biofilm formation and maturation. Antibacterial agent 333 exhibits activity against drug-resistant Vibrio strains. Antibacterial agent 333 lacks cytotoxicity toward mammalian cells and has no hemolytic activity. Antibacterial agent 333 can be used for the research of infection.
    Antibacterial agent 333
  • HY-B0992R
    Nithiamide (Standard)
    Inhibitor
    Nithiamide (Standard) is the analytical standard of Nithiamide. This product is intended for research and analytical applications. 0
    Nithiamide (Standard)
  • HY-168956
    Pks13-IN-2
    Inhibitor
    Pks13-IN-2 (Compound 43) is an orally active inhibitor of Pks13. Pks13-IN-2 exhibits inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 0.8-1.8 μM. Pks13-IN-2 shows good metabolic stability in mouse liver microsomes and hepatocytes. Pks13-IN-2 can be used for tuberculosis research.
    Pks13-IN-2
  • HY-W749146
    Raja 42
    Inhibitor
    Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains.
    Raja 42
  • HY-170312
    Antimicrobial-IN-1
    Inhibitor
    Antimicrobial-IN-1 (compound 17) exhibits strong antibacterial activity against S. aureus and E. coli, with the inhibition zone diameter of 18 , 16 mm/mg, respectively.
    Antimicrobial-IN-1
Cat. No. Product Name / Synonyms Application Reactivity