1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1360R
    Chlorquinaldol (Standard)
    Inhibitor
    Chlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells.
    Chlorquinaldol (Standard)
  • HY-121268R
    Demeclocycline (Standard)
    Inhibitor
    Demeclocycline (Standard) is the analytical standard of Demeclocycline (HY-121268). This product is intended for research and analytical applications. Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections.
    Demeclocycline (Standard)
  • HY-N8504
    Neoaureothin
    Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50=13 μM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50=1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s=34.3, 47, and 37.2 μg/mL, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50=0.84 μg/mL) and increases survival of P. densiflora trees inoculated with B. xylophilus.
    Neoaureothin
  • HY-19951A
    A-867191 hydrochloride
    Inhibitor
    A-867191 hydrochloride is a 2-pyridone DNA gyrase inhibitor. A-867191 hydrochloride has antibacterial activity. A-867191 hydrochloride can be used for research on infections.
    A-867191 hydrochloride
  • HY-B0101A
    Fluconazole hydrate
    Fluconazole (hydrate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
    Fluconazole hydrate
  • HY-N15059
    Cissetin
    Inhibitor
    Cissetin shows activity against Gram-positive bacteria, including drug-resistant strains.
    Cissetin
  • HY-120138
    BDM31827
    Inhibitor
    BDM31827 is an EthR inhibitor. BDM31827 can be used for multidrug-resistant-tuberculosis research.
    BDM31827
  • HY-N14077
    Monamycin D2
    Inhibitor
    Monamycin D2 is an ester peptide antibiotic. Monamycin D2 has activity against Gram-positive bacteria.
    Monamycin D2
  • HY-B0159R
    Balofloxacin (Standard)
    Inhibitor
    Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections.
    Balofloxacin (Standard)
  • HY-124431
    Kikumycin A
    Inhibitor
    Kikumycin A is an antibiotic, which can be generated from Streptomyces. Kikumycin A exhibits antibacterial activity against Gram-positive and Gram-negative bacteria. Kikumycin A exhibits antitrichomonal activity, with MIC of 25 μg/mL for Trichomonas foetus.
    Kikumycin A
  • HY-N0444R
    Rubiadin (Standard)
    Inhibitor
    Rubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections.
    Rubiadin (Standard)
  • HY-181935
    Antibiotic adjuvant 4
    Inhibitor
    Antibiotic adjuvant 4 (Compound 13) is an Antibiotic adjuvant and efflux pump inhibitor. Antibiotic adjuvant 4 exhibits potent efflux pump inhibitory activity. Antibiotic adjuvant 4 significantly downregulates virulence-related genes of Staphylococcus aureus when used alone or in combination with antibiotics. Antibiotic adjuvant 4 enhances the efficacy of Ciprofloxacin (HY-B0356) against multiagent-resistant Staphylococcus aureus strains.
    Antibiotic adjuvant 4
  • HY-17518R
    Valifenalate (Standard)
    Inhibitor
    Valifenalate (Standard) is the analytical standard of Valifenalate. This product is intended for research and analytical applications. Valifenalate (IR5885; Valiphenal) is an insecticide agent and fungicide, which is approved for application on high-value crops such as grapes, tomatoes and other vegetables. Valifenalate interferes with cell-wall synthesisValifenalate is effective against various types of mildew. Valifenalate can be used against crown rot of rose cuased by Phytophthora citrophthora. Valifenalate induces non-adverse thyroid changes via adaptive induction of uridine 5’-diphosphoglucuronosyltransferase (UGT) in the liver of dogs and rats.
    Valifenalate (Standard)
  • HY-169973
    PhoPS
    Inhibitor
    PhoPS is the photocaged inhibitor for β-lactamase. PhoPS is activated upon light irradiation, and active β-lactamase inhibitor Sulbactam (HY-B0334) is released. PhoPS inhibits the synthesis of bacterial cell wall and the formation of E. coli biofilm, exhibits antimicrobial activity.
    PhoPS
  • HY-W129661
    Pyrazine-2-carbothioamide
    Inhibitor 99.63%
    Pyrazine-2-carbothioamide is an effective antituberculosis agent with inhibitory activity against mycobacterium in vitro.
    Pyrazine-2-carbothioamide
  • HY-181819
    Antibacterial agent 327
    Inhibitor
    Antibacterial agent 327 (Compound 6f) is an Antibacterial agent. Antibacterial agent 327 potently inhibits the supercoiling activity of Staphylococcus aureus DNA gyrase with an IC50 of 0.28 μM. It also inhibits the ATPase activities of DNA gyrase and Topoisomerase IV, as well as the decatenation activity of Topoisomerase IV (IC50: 0.43 μM, 0.73 μM, and 2.31 μM, respectively). Antibacterial agent 327 potently inhibits Clostridioides difficile and methicillin-resistant Staphylococcus aureus (HY-121544), with an MIC of 0.78 μg/mL for both. Antibacterial agent 327 inhibits Escherichia coli with an MIC50 of 0.78 μg/mL.
    Antibacterial agent 327
  • HY-N14336
    Halomicin D
    Inhibitor
    Halomicin D is an ansamycin antibiotic. Halomicin A has activity against Gram-positive and Gram-negative bacteria (individual).
    Halomicin D
  • HY-135062
    9-Methylguanine
    Inhibitor
    9-Methylguanine, a derivative of 8-mercaptoguanine, is a dihydropteroate synthase (DHPS) inhibitor with a Kd of 58 μM for E.coli DHPS (EcDHPS).
    9-Methylguanine
  • HY-W140555
    5,7-Dimethoxyphthalide
    Inhibitor 99.97%
    5,7-Dimethoxyphthalide, a dimethoxy derivative of phthalide, can undergo nucleophilic substitution reactions with functionalized long-chain alkyl iodides. 5,7-Dimethoxyphthalide acts as a synthetic building block to prepare anti-Helicobacter pylori products including CJ molecule and sporotricale methyl ether. 5,7-Dimethoxyphthalide can be utilized for relevant researches on Helicobacter pylori infection and structure-activity relationship (SAR).
    5,7-Dimethoxyphthalide
  • HY-N14364
    Flavipucine
    Inhibitor
    Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells.
    Flavipucine
Cat. No. Product Name / Synonyms Application Reactivity