Integrin
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Integrin Inhibitors
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Integrin Antagonists
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Integrin Chemicals
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Integrin Inducers
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Integrin Ligands
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Integrin Produits associés (379)
Produits associés (379)
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Euchrestaflavanone A
0 ImagesCat. No.: HY-125123CAS No.: 80510-05-0Euchrestaflavanone A is a flavonoid found in the root bark of Cudrania tricuspidate. Euchrestaflavanone A inhibits platelet aggregation and has some antiplatelet and antithrombotic properties, making it a potential compound for thromboprophylaxis.
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VIP236
0 ImagesCat. No.: HY-164429CAS No.: 2418533-90-9VIP236 is a small-molecule drug conjugate targeting αvβ3 integrin. VIP236 achieves tumor homing via specific binding to αvβ3 integrin and delivers its payload to the tumor microenvironment. The linker of VIP236 is cleavable by neutrophil elastase, which is highly expressed in the tumor microenvironment, to release the payload 7-ethylcamptothecin. This payload induces DNA damage by inhibiting topoisomerase 1, thereby exerting anti-tumor effects. VIP236 exhibits excellent plasma stability and tumor targeting property, with a tumor/plasma payload ratio 10-fold higher than that of the single administration. It effectively induces tumor regression, reduces metastasis formation, and shows good tolerance in mouse models. VIP236 has been used in studies related to non-small cell lung cancer, clear cell renal cell carcinoma, colon cancer, triple-negative breast cancer, small cell lung cancer, and metastatic solid tumors.
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HYNIC-3P-RGD2
0 ImagesCat. No.: HY-P11774CAS No.: 1094848-99-3HYNIC-3P-RGD2 is a dimeric cyclic RGD peptide with high binding affinity for integrin αvβ3 (IC50 = 33 nM). HYNIC-3P-RGD2 acts as a precursor molecule for radiotracers and is used to detect tumor angiogenesis.
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A20FMDV2-Cys
0 ImagesCat. No.: HY-P1654ACAS No.: 3107375-56-1
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HB-3-20
0 ImagesCat. No.: HY-P10677HB-3-20 leads to degradation of the cell surface integrin αVβ5. Transglutaminase 2 (TG2) has specificity for HB-3-20 (kcat/KM=0.16 μM-1min-1).
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Dihydropelitinib
0 ImagesCat. No.: HY-184113Synonyms: DHPDihydropelitinib (DHP) is a ILK ligand with a Kd value of 252 nM. Dihydropelitinib acts as a cytoskeleton modulator that induces actin (Actin) cytoskeleton rearrangement. Dihydropelitinib exhibits anticancer activity against liver cancer and lung adenocarcinoma. Dihydropelitinib can be used in studies related to liver cancer and lung adenocarcinoma.
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Anti-CD103 Antibody (hCD103.01A)
0 ImagesCat. No.: HY-P992051Anti-CD103 Antibody (hCD103.01A) is a monoclonal antibody targeting human CD103 and can be used in cancer immunotherapy and immunological research. Recommend Isotype Controls: human IgG1 kappa, Isotype Control (HY-P99001).
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BI-1950
0 ImagesCat. No.: HY-124040CAS No.: 1159724-42-1BI-1950 is a lymphocyte function-associated antigen 1 (LFA-1) inhibitor. BI-1950 regulates immune system function through interaction with LFA-1. BI-1950 can be used in the research of inflammatory diseases.
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D-RGDW
0 ImagesCat. No.: HY-P11384CAS No.: 144161-76-2D-RGDW is an Arg-Gly-Asp (RGD) containing peptide. D-RGDW inhibits αIIbβ3 mediated platelet aggregation.
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AFP464
0 ImagesCat. No.: HY-16031ACAS No.: 468719-53-1Synonyms: NSC710464AFP464 (NSC710464) is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 is applicable to research related to breast cancer.
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Dentonin TFA
0 ImagesCat. No.: HY-P2633ASynonyms: AC-100 TFADentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism.
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Tris-ανβ6 integrin ligand-1
0 ImagesCat. No.: HY-185467CAS No.: 3047235-29-7
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Lotrafiban hydrochloride
0 ImagesCat. No.: HY-10314ACAS No.: 179599-82-7Synonyms: SB-214857-ALotrafiban hydrochloride is an orally-active platelet GPIIb/IIIa blocker for research of coronary and cerebrovascular disease.
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ATL 1102 sodium
0 ImagesCat. No.: HY-153481ASynonyms: ISIS-107248 sodium; Avicursen sodiumATL 1102 (Avicursen) sodium is a novel second-generation antisense oligonucleotide to CD49d mRNA
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Roxifiban
0 ImagesCat. No.: HY-10307CAS No.: 170902-47-3Roxifiban is a platelet glycoprotein (GP) IIb/IIIa receptor inhibitor that can be used in the study of angina.
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Anti-Fibulin-4 Antibody (5G11)
0 ImagesCat. No.: HY-P991850Anti-Fibulin-4 Antibody (5G11) reacts with the human fibulin-4. Anti-Fibulin-4 Antibody (5G11) does not show any crossreactivity with other family members. Fibulin-4 is an elastic-fibre-associated glycoprotein.
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Crocatin B
0 ImagesCat. No.: HY-N15519CAS No.: 143816-02-8Crocatin B is found in P. crocatum Ruiz & Pav. Crocatin B exerts anti-inflammatory activity by inhibiting the expression of TNF-α and ICAM-1. Crocatin B has anti-tumor activity.
