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Art. -Nr.: HY-118410

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L-738167

L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research.

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CAS. Nr.: 163212-43-9
Formel: C₂₅H₃₄N₆O₆S
Molecular Weight:546.64

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

L-738167 Chemical Structure

CAS. Nr.: 163212-43-9

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG) Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)	[PMID: 9191954]
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin	[PMID: 9191954]
HUVEC	IC₅₀	>3 nM Compound: 5	Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN) Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)	[PMID: 9191954]

Chemical Information

CAS. Nr. 163212-43-9
Molecular Weight 546.64
Formel C₂₅H₃₄N₆O₆S
SMILES

O=C(O)[C@H](CNC(C1=NN2C(C(N(CCC3CCNCC3)CCC2)=O)=C1)=O)NS(=O)(C4=CC=C(C)C=C4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Terence G, et al. Non-peptide fibrinogen receptor antagonists. 21. The synthesis of [3H]L-738,167. Journal of Labelled Compounds and Radiopharmaceuticals. Volume41, Issue4. April 1998

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
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L-738167

Alle Integrin Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

L-738167 Related Classifications

HY-118410 Related Classifications