Interleukin Related
IL
Interleukins are a group of cytokines (secreted proteins and signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4 T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.
Interleukin Related Isoform Specific Products
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Interleukin Related
(947)
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IL-1
(468)
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IL-2
(116)
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IL-3
(8)
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IL-4
(83)
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IL-5
(33)
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IL-6
(493)
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IL-8
(101)
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IL-10
(87)
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IL-12
(40)
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IL-13
(51)
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IL-15
(9)
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IL-17
(102)
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IL-23
(38)
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IL-7
(14)
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IL-33
(5)
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IL-22
(11)
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IL-18
(21)
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All Product Categories
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Interleukin Related Inhibitors
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Interleukin Related Agonists
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Interleukin Related Antagonists
(34)
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Interleukin Related Activators
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Interleukin Related Modulators
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Interleukin Related Chemicals
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Interleukin Related Inducers
(62)
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Interleukin Related Degraders
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Interleukin Related Controls
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Interleukin Related Ligands
(10)
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IL-4 Proteins
(26)
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IL-12 Proteins
(39)
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IL-17 Proteins
(71)
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IL-8/CXCL8 Proteins
(16)
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Multi-CSF/IL-3 Proteins
(18)
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IL-1 Proteins
(43)
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IL-2 Proteins
(22)
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IL-5 Proteins
(20)
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IL-6 Proteins
(24)
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IL-10 Proteins
(16)
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IL-13 Proteins
(19)
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IL-15 Proteins
(18)
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IL-23 Proteins
(22)
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Interleukin Related Related Products (2213)
Related Products (2213)
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Recombinant Proteins (352)
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Antibodies (36)
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Interleukin Related Isoform Comparison
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(±)-Lisofylline (Standard)
0 ImagesSynonyms: (±)-Lisophylline (Standard)(±)-Lisofylline (Standard) is the analytical standard of (±)-Lisofylline. This product is intended for research and analytical applications. (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research.
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4,5-Dehydro-6-oxoallosecurinine
0 ImagesCat. No.: HY-1818184,5-Dehydro-6-oxoallosecurinine is a Keap1-Nrf2 pathway activator. 4,5-Dehydro-6-oxoallosecurinine promotes the nuclear translocation of Keap1-Nrf2, and induces the expression of antioxidant and cytoprotective genes. 4,5-Dehydro-6-oxoallosecurinine reduces the production of NO, and decreases the levels of iNOS, TNF-α, IL-6 and IL-1β in LPS-stimulated microglia. 4,5-Dehydro-6-oxoallosecurinine can be used for the research of neurodegenerative diseases.
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Anti-IL-32 Antibody
0 ImagesCat. No.: HY-P992248
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Fosfenopril (Standard)
0 ImagesSynonyms: Fosinoprilat (Standard); Fosinoprilic acid (Standard); SQ 27519 (Standard)Fosfenopril (Standard) is the analytical standard of Fosfenopril. This product is intended for research and analytical applications. Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes.
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Anti-neuroinflammation agent-4
0 ImagesCat. No.: HY-189271CAS No.: 3113312-38-9Anti-neuroinflammation agent-4 is a blood-brain barrier-penetrating inhibitor of IκBα, NLRP3, and NF-κB p65. Anti-neuroinflammation agent-4 exerts anti-neuroinflammatory effects by inhibiting IκBα phosphorylation, reducing NLRP3 and caspase-1 expression, and suppressing p65 phosphorylation and its nuclear translocation, thereby decreasing the release of inflammatory mediators such as ROS, NO, IL-1β, IL-6, TNF-α, and IL-18 in microglia. Anti-neuroinflammation agent-4 can be used for research on neuroinflammation.
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Dazupegleukin
0 ImagesCat. No.: HY-P992106CAS No.: 3049254-88-5Dazupegleukin is an interleukin-2 derivative with antineoplastic properties.
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Taxamairin B
0 ImagesCat. No.: HY-N12042CAS No.: 110300-77-1Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice.
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(±)19(20)-EDP ethanolamide
0 ImagesCat. No.: HY-138970CAS No.: 2123485-34-5Synonyms: 19,20-DHEA epoxide; 19,20-Epoxy docosapentaenoic acid ethanolamide; 19,20-EDP-EA(±)19(20)-EDP ethanolamide (19,20-DHEA epoxide) (compound 19) is an ω-3 endocannabinoid epoxide with cytokine modulation in neuroinflammation studies, antiangiogenic effects in vascular endothelial cells, and vasodilatory effects on coronary arteries.
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Anti-IL-31 Antibody
0 ImagesCat. No.: HY-P992247Anti-IL-31 Antibody is a monoclonal antibody that targets IL-31. Anti-IL-31 Antibody can be used in ELISA, FACS, and functional assays.
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PPARγ agonist 20
0 ImagesCat. No.: HY-178447PPARγ agonist 20 is a potent, orally active PPAR-γ agonist. PPARγ agonist 20 effectively increases antioxidant defenses (SOD, GSH) and reduces lipid peroxidation. PPARγ agonist 20 can upregulate of Pparg, Glut4, and AdipoQ, suppresses of TNF-α, IL-6, and NF-κB p65. PPARγ agonist 20 significantly lowers fasting blood glucose, improving glucose tolerance, and restoring metabolic balance in Streptozotocin (HY-13753)-Nicotinamide (HY-B0150)-induced diabetic rats. PPARγ agonist 20 can be used for the study of type 2 diabetes.
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Il10 Mouse Pre-designed siRNA Set A
0 ImagesCat. No.: HY-RS06671Il10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Undecane-d24
0 ImagesCat. No.: HY-N8593SCAS No.: 164858-54-2Undecane-d24 is the deuterium labeled Undecane (HY-N8593).Undecane is a potent cAMP agonist with anti-allergic and anti-inflammatory activities. Undecane inhibits degranulation and the secretion of histamine and TNF-α. Undecane reverses the increased levels of p38 phosphorylation, NF-κB transcriptional activity and target cytokine/chemokine genes, including thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and interleukin-8 (IL-8). Undecane can be used for the study of skin inflammatory disorders, such as atopic dermatitis.
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EP4 receptor antagonist 8
0 ImagesCat. No.: HY-178465CAS No.: 3068255-86-4EP4 receptor antagonist 8 is an orally active EP4 antagonist (human EP4 IC50 = 6.40 nM). EP4 receptor antagonist 8 significantly reduced paw and joint swelling, inflammatory cell infiltration, cartilage damage, pannus formation, and joint bone erosion in arthritis (AIA) mice in a dose-dependent manner. EP4 receptor antagonist 8 can be used for the study of inflammatory pain.
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Sodium chloride, United States Pharmacopeia (USP) Reference Standard
0 ImagesSodium chloride, United States Pharmacopeia (USP) Reference Standard is an orally active salt. Sodium chloride, United States Pharmacopeia (USP) Reference Standard induces the expression of ATP1A1. Sodium chloride, for cell culture induces the pro-inflammatory cytokines IL-2, TNFα, IL-9 and several chemokines. Sodium chloride, United States Pharmacopeia (USP) Reference Standard enhances the anti-tumor activities of Digoxin (HY-B1049) against small cell lung cancer. Sodium chloride, United States Pharmacopeia (USP) Reference Standard drives autoimmune disease by the induction of pathogenic Th17 cells.
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FB-825
0 ImagesCat. No.: HY-P991256FB-825 is a human monoclonal antibody (mAb) targeting IGHE. FB-825 targets the CεmX domain of membrane IgE (mIgE), resulting in the downregulation of mIgE-positive B cells and the production of IgE. FB-825 can be used in Allergic asthma, Atopic dermatitis, Job syndrome and Allergic rhinitis research.
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5-Hydroxy-6,7-dimethoxyflavone
0 Images5-Hydroxy-6,7-dimethoxyflavone is an orally active inhibitor of ferroptosis (Ferroptosis). 5-Hydroxy-6,7-dimethoxyflavone inhibits H1N1 virus-induced ferroptosis by upregulating the expression of SLC7A11 and GPX4. 5-Hydroxy-6,7-dimethoxyflavone alleviates inflammatory responses and inhibits apoptosis by suppressing the activation of the NF-κB and p38 MAPK signaling pathways. 5-Hydroxy-6,7-dimethoxyflavone can be used in studies related to H1N1 influenza virus infection.
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Antiflammin-1
0 ImagesCat. No.: HY-P1931CAS No.: 118850-71-8Synonyms: Uteroglobin(39-47)Antiflammin-1 is an anti-inflammatory peptide 1 (MQMKKVLDS). Antiflammin-1 is a derivative of uteroglobin. Antiflammin-1 has anti-inflammatory and antifibrotic actions in bleomycin (HY-108345)-induced lung injury.
