2. Epigenetics Metabolic Enzyme/Protease
  3. Epigenetic Reader Domain Apolipoprotein
  4. GW 841819X

GW 841819X is a potent inducer of the ApoA1 report gene, with an EC170 of 0.22 µM, and its pIC50 for Brd2/3/4 is 5.9/6.2/6.3.

For research use only. We do not sell to patients.

GW 841819X

GW 841819X Chemical Structure

CAS No. : 146135-18-4

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GW 841819X Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE GW 841819X

View All Apolipoprotein Isoform Specific Products:

View All Isoforms
apoE apoB apoA1 apoA2 apoA4 apoC1 apoC2 apoC3

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Description

GW 841819X is a potent inducer of the ApoA1 report gene, with an EC170 of 0.22 µM, and its pIC50 for Brd2/3/4 is 5.9/6.2/6.3[1].

IC50 & Target

apoA1

 

Cellular Effect
Cell Line Type Value Description References
HepG2 EC50
440 nM
Compound: 1, GW841819X
Induction of human ApoA1 gene expression in stably transfected human HepG2 cells coexpressing luciferase reporter gene after 18 hrs by luminescence assay
Induction of human ApoA1 gene expression in stably transfected human HepG2 cells coexpressing luciferase reporter gene after 18 hrs by luminescence assay
[PMID: 21568322]
Molecular Weight

423.47

Formula

C25H21N5O2
CAS No.
SMILES

CC1=NN=C2N1C3=CC=CC=C3C(C4=CC=CC=C4)=NC2NC(OCC5=CC=CC=C5)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GW 841819X Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GW 841819X146135-18-4Epigenetic Reader DomainApolipoproteinInhibitorinhibitorinhibit

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HY-13031
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