Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2567)
Related Products (2567)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
AZ960
0 ImagesCat. No.: HY-10411CAS No.: 905586-69-8AZ960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM.
-
Eprinomectin
0 ImagesSynonyms: MK-397Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity.
-
4-Amino-L-phenylalanine
0 ImagesSynonyms: H-Phe(4-NH2)-OH4-Amino-L-phenylalanine (H-Phe(4-NH2)-OH) is a metabolic intermediate and an α-carbonic anhydrase (TcCA) activator with a Ka value of 0.75 μM. 4-Amino-L-phenylalanine acts through active site cavity entrance binding and a proton shuttle mechanism to enhance the catalytic rate of CO2 hydration. 4-Amino-L-phenylalanine serves as a diamine monomer for bio-based polymer synthesis and is produced in Escherichia coli via the shikimate pathway. 4-Amino-L-phenylalanine constitutes a structural component of haptens used in immunoassay development. 4-Amino-L-phenylalanine is used for the production of Chloramphenicol (HY-B0239) and Pristinamycin I in Streptomyces venezuelae and S. pristinaespiralis, respectively. 4-Amino-L-phenylalanine is used in research related to Trypanosoma cruzi infection.
-
Benzyl isothiocyanate
0 ImagesBenzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia.
-
Oxantel pamoate
0 ImagesSynonyms: Oxantel embonateOxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM).
-
(R)-(-)-2-Phenylglycinol
0 ImagesSynonyms: D-Phenylglycinol; (-)-Phenylglycinol(R)-(-)-2-Phenylglycinol (D-Phenylglycinol; (-)-Phenylglycinol) is a chiral β-amino alcohol, a starting material for chiral synthesis, and a potential nematicide. (R)-(-)-2-Phenylglycinol exhibits nematicidal and egg hatching inhibitory activity against the southern root-knot nematode (Meloidogyne incognita), and is also an upregulated metabolite in the fermentation broth of Streptomyces aquilus JXGZ01. (R)-(-)-2-Phenylglycinol can be used as a framework for constructing zwitterionic bicyclic lactams and multi-substituted piperidine/piperidine acid drugs. (R)-(-)-2-Phenylglycinol can be used in drug synthesis and nematode infection-related research.
-
Diethyltoluamide
0 ImagesDiethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction.
-
Tioconazole
0 ImagesSynonyms: UK-20349Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy.
-
Isomaltose
0 ImagesSynonyms: 6-O-α-D-Glucopyranosyl-D-glucose; D-IsomaltoseIsomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection.
-
Azithromycin hydrate
0 ImagesSynonyms: CP-62993 hydrateAzithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
-
Albendazole sulfoxide
0 ImagesSynonyms: Ricobendazole; Albendazole oxideAlbendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
-
Quinine sulfate
0 ImagesQuinidine sulfate is an antiarrhythmic agent. Quinidine sulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine sulfate can be used for malaria research.
-
DAUDA
0 ImagesDAUDA is a fluorescent fatty acid analog probe, with Kd values of 0.63 μM, 0.82 μM, and 0.66 μM against subtypes/mutants of Schistosoma mansoni Sm14 fatty acid-binding protein, respectively. DAUDA binds to Sm14 fatty acid-binding protein variants, enters their non-polar binding pockets and alters fluorescence emission properties. DAUDA serves as a tracer in competitive binding assays with natural fatty acids to evaluate the fatty acid-binding capacity of Sm14 protein variants. DAUDA is applicable to the research of schistosomiasis.
-
Hexylresorcinol
0 ImagesHexylresorcinol (4-Hexylresorcinol) is a natural compound found in plants with antimicrobial, anthelmintic, antiseptic and antitumor activities. Hexylresorcinol can induce apoptosis in squamous carcinoma cells. Hexylresorcinol is a reversible and noncompetitive inhibitor of α-glucosidase. Hexylresorcinol has protective effects against oxidative DNA damage.
-
Piperaquine tetraphosphate tetrahydrate
0 ImagesPiperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. Piperaquine tetraphosphate tetrahydrate can be used in antimalarial research in combination with Artemisinin.
-
D-Carnitine
0 ImagesD-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity.
-
α-Thujone
0 Imagesα-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and can cross the blood-brain barrier.
-
Nemadectin
0 ImagesSynonyms: CL-287088; LL-F28249 αNemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
