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Wnt Related Products (345)
Related Products (345)
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AXIN2/β-catenin-IN-1
0 ImagesCat. No.: HY-180449CAS No.: 3004884-16-3Anticancer agent 291 (Compound 2406) is an anti-cancer agent. Anticancer agent 291 interferes with the integrity of the β-tubulin cytoskeleton and inhibits the Wnt/β-catenin signal transduction. Anticancer agent 291 significantly inhibits the invasion, migration and colony formation of tumor cells. Anticancer agent 291 induces the cell cycle of EC-9706 and HT-29 cells to arrest at the G2/M phase and inhibits cell proliferation. Anticancer agent 291 can be used for the study of gastrointestinal cancer.
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KY1022
0 ImagesCat. No.: HY-113680CAS No.: 1029721-36-5KY1022 is a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway. KY1022 can inhibit cellular EMT, metastasis and apoptosis. KY1022 can be used for the research of metastatic colorectal cancer.
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SEN461
0 ImagesCat. No.: HY-120864CAS No.: 1287727-28-9SEN461 is a potent and orally active Wnt pathway inhibitor. SEN461 shows effective anti-tumor activity and can be used for GBM research.
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Anti-DKK2 Antibody
0 ImagesCat. No.: HY-P992224
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Apoptosis inducer 22
0 ImagesCat. No.: HY-161900Apoptosis inducer 22 (QR-5) is an apoptosis inducer with IC50 values of 63.1 and 46.5 μM for colon cancer cell lines SW480 and HT29, respectively. Apoptosis inducer 22 induces apoptosis by inhibiting the Wnt/β-catenin axis in colon cancer cells. Apoptosis inducer 22 can be used in anti-colon cancer research.
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21H7
0 ImagesCat. No.: HY-169671CAS No.: 217317-45-821H7 is a selective inhibitor of the Wnt/b-catenin pathway. 21H7 markedly inhibits the growth of HFs. 21H7 potently decreases growth of breast and colon cancer cells.
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Anti-LRP5 Antibody
0 ImagesCat. No.: HY-P992263
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Pamidronic acid sodium
0 ImagesCat. No.: HY-B0012BCAS No.: 89131-02-2Pamidronic acid sodium, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronic acid sodium significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronic acid sodium can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.
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β-catenin-IN-7
0 ImagesCat. No.: HY-149858CAS No.: 2952779-17-6
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Viridicatol (Standard)
0 ImagesCat. No.: HY-116474RCAS No.: 14484-44-7Viridicatol (Standard) is the analytical standard of Viridicatol (HY-116474). This product is intended for research and analytical applications. Viridicatol is a quinolone alkaloid with anti-inflammatory, antibacterial, antifungal, osteogenic and chondrogenic activities. Viridicatol reduces the phosphorylation levels of ERK, JNK, p38 and STAT6; inhibits MMP-2, MMP-9, NF-κB signaling pathway and PTP1B; downregulates genes related to mast cell activation; and binds to SHN3 to activate the Wnt/SHN3 signaling pathway. Viridicatol inhibits the expression of pro-inflammatory mediators and cytokines, and promotes osteogenic/chondrogenic differentiation. Viridicatol can be used in studies related to fibrosarcoma, allergy, bacterial infection, fungal infection and osteoporosis.
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Combretastatin A-1 phosphate tetrasodium
0 ImagesCat. No.: HY-16146CAS No.: 288847-34-7Synonyms: OXi-4503 tetrasodiumCombretastatin A-1 phosphate (OXi-4503) tetrasodium, a proagent of Combretastatin A-1, is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 phosphate tetrasodium inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 phosphate tetrasodium exhibits anti-tumor and anti-vascular effects.
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TWS119 TFA
0 ImagesCat. No.: HY-110074CAS No.: 1507095-58-0TWS119 TFA is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.
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YW2036
0 ImagesYW2036 (compound 2a) is a potent Wnt/β-Catenin signaling pathway inhibitor with an IC50 value of 637 nM. YW2036 can be used in research of colorectal cancer (CRC).
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hsBCL9CT-24
0 ImagesCat. No.: HY-P10652CAS No.: 2094604-98-3
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PI3Kα-IN-16
0 ImagesCat. No.: HY-161140CAS No.: 1448711-61-2
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CDK8-IN-11 hydrochloride
0 ImagesCat. No.: HY-151463A
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Methyl vanillate (Standard)
0 ImagesMethyl vanillate (Standard) is the analytical standard of Methyl vanillate. This product is intended for research and analytical applications. Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
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UM206_C
0 ImagesCat. No.: HY-P11867ACAS No.: 1242439-01-5UM206_C is a circular Wnt fragment peptide derived from conserved Wnt3a/Wnt5a sequences, inactive in soluble form but capable of activating canonical Wnt/β-catenin signaling when conjugated to magnetic nanoparticles and exposed to a high-gradient, time-varying magnetic field or immobilized on glass surfaces.
