Transmembrane Glycoprotein
Transmembrane Glycoprotein
Transmembrane glycoproteins are important components of cell membranes and are characterized by oligosaccharide chains covalently linked to polypeptide chains. Glycosylation sites are mainly located in their extracellular regions, achieved by N-linked glycosylation (linked to asparagine residues) or O-linked glycosylation (linked to serine or threonine residues). Sugar chains not only provide structural stability to proteins but also confer functional specificity. Many transmembrane glycoproteins are receptors, such as G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). Most （clusters of differentiation）CD molecules are also transmembrane glycoproteins expressed on the surface of antigen-presenting cells[1][2].
References:
- [1]. L Franco, et al. The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes. FASEB J. 1998 Nov;12(14):1507-20. [Content Brief]
- [2]. Kumi Oshima, et al. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett. 2002 May 22;519(1-3):1-7. [Content Brief]
All Product Categories
-
Transmembrane Glycoprotein Inhibitors
(234)
View all products
-
Transmembrane Glycoprotein Agonists
(8)
View all products
-
Transmembrane Glycoprotein Antagonists
(7)
View all products
-
Transmembrane Glycoprotein Activators
(10)
View all products
-
Transmembrane Glycoprotein Modulators
(5)
View all products
-
Transmembrane Glycoprotein Ligands
(16)
View all products
-
Transmembrane Glycoprotein Related Products (380)
Related Products (380)
-
Anti-UPK-1B Antibody
0 ImagesCat. No.: HY-P992310
-
BAT-6021
0 ImagesCat. No.: HY-P991390BAT-6021 is a human monoclonal antibody (mAb) targeting TIGIT. BAT-6021 can be used in Solid tumours research.
-
EU101
0 ImagesCat. No.: HY-P992044Synonyms: NOV1801EU101 (NOV1801) is a humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137, with potential immunostimulatory and antineoplastic activities.
-
ASP8374
0 ImagesCat. No.: HY-P991393
-
ABB071
0 ImagesCat. No.: HY-P991956ABB071 is a humanized anti-CD180 monoclonal antibody. ABB071 can down-regulate the highly expressed TLR7 and IRF5 genes in systemic lupus erythematosus and induce the expression of PNPT1 and DNASE1L3 genes. ABB071 can inhibit the expression of genes related to the type I interferon pathway as well as interferon-stimulated genes (ISGs). ABB071 has anti-inflammatory activity and can reduce the levels of inflammatory cytokines. ABB071 can be used for research on systemic lupus erythematosus and psoriasis.
-
AK-001
0 ImagesCat. No.: HY-P991071AK-001 is a fully human IgG1 antibody that targets Siglec-8. VRC-01 can be used for the study of chronic rhinosinusitis with nasal polyps. The isotype control for AK-001 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
-
Anti-Mouse TIM-1/CD365 Antibody (3B3)
0 ImagesCat. No.: HY-P990154Anti-Mouse TIM-1/CD365 Antibody (3B3) is a rat-derived IgG2a κ type agonistic antibody, targeting to mouse TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3B3) enhances T-cell proliferation and responses by forming a stable TIM-1 complex and bringing TIM-1 into the T-cell receptor (TCR)-CD3 complex. Anti-Mouse TIM-1/CD365 Antibody (3B3) can be used for the researches of cancer, inflammation and immunology, such as experimental autoimmune encephalomyelitis, B16 F10 tumor and transplant.
-
Anti-CD32b Antibody (HuMax-CD32b)
0 ImagesCat. No.: HY-P991527Anti-CD32b Antibody (HuMax-CD32b) is a humanized antibody against CD32b.
-
Anti-CD300C Antibody
0 ImagesCat. No.: HY-P992208
-
Anti-Plexin A1 Antibody
0 ImagesCat. No.: HY-P992292
-
Anti-Canine CD34 Antibody (1H6)
0 ImagesCat. No.: HY-P990274Anti-Canine CD34 Antibody (1H6) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to canine CD34. Anti-Canine CD34 Antibody (1H6) reacts with canine CD34. Anti-Canine CD34 Antibody (1H6) can be used for the separation and identification of CD34+ cells. Anti-Canine CD34 Antibody (1H6) can be used for detections of western blot, immunohistochemistry and flow cytometry.
-
Anti-CD317 Antibody (HM1.24 )
0 ImagesCat. No.: HY-P991885Anti-CD317 Antibody (HM1.24 ) is an antibody against human BST2/CD317. Recommend Isotype Controls:?Rat IgG2b kappa, Isotype Control (HY-P990682).
-
Anti-L1-CAM Antibody
0 ImagesCat. No.: HY-P992253
-
B18 peptide
0 ImagesCat. No.: HY-P12375CAS No.: 3027663-77-7B18 peptide is a cationic amphipathic α-helical peptidomimetic that binds to the BST-2 extracellular domain and forms a stable complex through intermolecular hydrogen bonds near the N-terminus. B18 peptide competitively inhibits the binding of BST-2 to the extracellular matrix via its extracellular domain, reducing migrasome formation. B18 peptide induces membrane lysis through the formation of pores/water channels and annular pores, impairing membrane integrity. B18 peptide exhibits anticancer activity against breast cancer. B18 peptide can be used for research on breast cancer.
-
Anti-TMEFF2 Antibody
0 ImagesCat. No.: HY-P990523Anti-TMEFF2 Antibody is a humanized antibody expressed in CHO cells, targeting TMEFF2. The Anti-TMEFF2 Antibody features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-TMEFF2 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
-
Anti-CD86 Antibody (3D1)
0 ImagesCat. No.: HY-P991908
-
PD1-PDL1-IN-4
0 ImagesCat. No.: HY-185098CAS No.: 2007110-15-6PD1-PDL1-IN-4 (compound 19) is a potent and orally active PD1-PDL1 inhibitor that modulates TIGIT and PD-1 signalling pathways. PD1-PDL1-IN-4 can rescue CD8+ T cell and mouse splenocyte proliferation. PD1-PDL1-IN-4 inhibits tumor growth in a CT26 syngeneic colon adenocarcinoma mouse model. PD1-PDL1-IN-4 can be used for research on colon cancer.
-
Glycotriosyl glutamine
0 ImagesCat. No.: HY-126800CAS No.: 83235-86-3Glycotriosyl glutamine is a synthetic analogue of the Glycopeptide. Glycotriosyl glutamine induces focal glomerulonephritis (FGN) and the appearance of myeloid bodies in the epithelial cells of the podocytes in rats with nephritogenic activity.
-
Anti-CD99 Antibody
0 ImagesCat. No.: HY-P992216
-
WM-A1-3389
0 ImagesCat. No.: HY-P992021WM-A1-3389 is an anti-human IGSF1monoclonal antibody and tumor growth inhibitor. WM-A1-3389 specifically binds to the C-terminus of IGSF1, increases secretion of Granzyme B, IFN?γ, and TNF?α, and inhibits growth of colon cancer or biliary tract cancer in xenogeneic or allogeneic mouse implantation models. WM-A1-3389 can be used for the research of colon cancer, biliary tract cancer, and head and neck cancer.
