Antiproliferative agent-42
Antiproliferative agent-42 (compound 7m) is a dihydrodipyrrolo compound. Antiproliferative agent-42 showed antiproliferative activity against Panc-1 cell line with an IC50 value of 12.54 μM.
For research use only. We do not sell to patients.
- CAS No.: 3002404-74-9
- Formula: C18H13N5O4
- Molecular Weight:363.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Antiproliferative agent-42 (0-100 μM, 48 h) can inhibit Panc-1 and PC3 as well as MDA-MB-231 cell lines with IC50 values of 12.5 μM, 17.7 μM, and 13.1 μM, respectively[1].
Antiproliferative agent-42 (12.54 μM, 48 h) can induce sub-G1 phase arrest in Panc-1 cancer cells[1].
Antiproliferative agent-42 (12.54 μM) turns down the protein lever of cleaved-caspase-3 and caspase-3 in Panc-1 cancer cells, while the protein lever of pro-caspase-3 retains unchanged in Panc-1 cancer cells [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Panc-1
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Concentration:12.54 μM
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Incubation Time:48 h
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Result:Induced apoptosis at 15.54 μM concentration (11.1%).
Chemical Information
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CAS No. 3002404-74-9
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Molecular Weight 363.33
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Formula C18H13N5O4
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SMILES
O=C1NNC(C2=C1C(C3=CC([N+]([O-])=O)=CC=C3)=C4N2CCN5C4=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiproliferative agent-42 Related Classifications
HY-155402 Related Classifications
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