1. Protein Tyrosine Kinase/RTK
  2. Bcr-Abl Src
  3. AP 24149

AP 24149 is a potent Src-Abl dual inhibitor with IC50 values of 9.1, 3.6 nM for Src and Abl, respectively.

For research use only. We do not sell to patients.

AP 24149 Chemical Structure

AP 24149 Chemical Structure

CAS No. : 926922-29-4

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Description

AP 24149 is a potent Src-Abl dual inhibitor with IC50 values of 9.1, 3.6 nM for Src and Abl, respectively[1].

IC50 & Target[1]

Abl

3.6 nM (IC50)

Src

9.1 nM (IC50)

Molecular Weight

417.44

Formula

C23H24N5OP

CAS No.
Unlabeled CAS

SMILES

O=P(C)(C)C(C=C1)=CC=C1NC2=C3N=CN(/C=C/C4=C(C)C=CC=C4C)C3=NC=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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AP 24149 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AP 24149
Cat. No.:
HY-10363
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