Ageconyflavone C
Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC50 values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research.
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- CAS. Nr.: 93124-90-4
- Formel: C20H20O8
- Molecular Weight:388.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Ageconyflavone C (compound 5) (>30 μg/mL; >90 μg/mL) exhibits moderate in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense (IC50 = 7.8 μM), Leishmania donovani (IC50 = 9.2 μM), and Plasmodium falciparum (IC50 = 9.25 μM), with no activity against Trypanosoma cruzi and no cytotoxicity against L6 rat skeletal myoblasts at the highest tested concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 93124-90-4
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Molecular Weight 388.37
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Formel C20H20O8
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SMILES
O=C1C=C(C2=CC(OC)=C(O)C(OC)=C2)OC3=C1C(OC)=C(OC)C(OC)=C3
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)