Ch282-5
Ch282-5 is an orally active inhibitor targeting the Bcl-2 protein, inducing mitochondria-dependent apoptosis (Apoptosis) by disrupting mitophagy and the mTOR pathway. Ch282-5 exhibits antiproliferative activity against colorectal cancer cells both in vitro and in vivo, and it also inhibits metastasis. Additionally, Ch282-5 enhances Oxaliplatin (HY-17371)-induced autophagy (Autophagy) by downregulating the Mcl-1 protein and increasing platelet count, alleviating adverse effects of Navitoclax (HY-10087).
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- CAS. Nr.: 65891-87-4
- Formel: C34H34N2Na2O14S2
- Molecular Weight:804.75
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 65891-87-4
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Molecular Weight 804.75
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Formel C34H34N2Na2O14S2
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SMILES
CC(C1=C(O)C(O)=C(/C=N/CCS(=O)(O[Na])=O)C(C(C(C(C2=O)=C(C)C(C3=C2C(/C=N/CCS(=O)(O[Na])=O)=C(O)C(O)=C3C(C)C)=O)=C4C)=O)=C1C4=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ch282-5 Related Classifications
HY-164468 Related Classifications
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