Art. -Nr.: HY-B0825

(E)-Fenpyroximate

Name: (E)-Fenpyroximate
Brand: MedChemExpress
SKU: HY-B0825
Price: 50.00 USD
Availability: InStock
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(E)-Fenpyroximate is a potent acaricide.

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Reinheit : 98.09%
CAS. Nr.: 134098-61-6
Formel: C₂₄H₂₇N₃O₄
Molecular Weight:421.49

Speicherung:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

(E)-Fenpyroximate Chemical Structure

CAS. Nr.: 134098-61-6

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
- In Vivo
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

(E)-Fenpyroximate is a potent acaricide^[1].

IC₅₀ & Target

Mite

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Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.12 μg/mL Compound: 36	Cytotoxic activity against A549 cell line (non-small cell lung carcinoma) Cytotoxic activity against A549 cell line (non-small cell lung carcinoma)	[PMID: 15922597]
HCT-15	IC₅₀	0.02 μg/mL Compound: 36	Cytotoxic activity against HCT15 cell line (human colon solid tumor cell line) Cytotoxic activity against HCT15 cell line (human colon solid tumor cell line)	[PMID: 15922597]
SK-MEL-2	IC₅₀	13.27 μg/mL Compound: 36	Cytotoxic activity against SKMEL-2 cell line Cytotoxic activity against SKMEL-2 cell line	[PMID: 15922597]
SK-OV-3	IC₅₀	0.21 μg/mL Compound: 36	Cytotoxic activity against SKOV-3 cell line (human solid ovarian tumor cell line) Cytotoxic activity against SKOV-3 cell line (human solid ovarian tumor cell line)	[PMID: 15922597]
XF498	IC₅₀	0.04 μg/mL Compound: 36	Cytotoxic activity against XF498 cell line (human CNS solid tumor) Cytotoxic activity against XF498 cell line (human CNS solid tumor)	[PMID: 15922597]

Chemical Information

CAS. Nr. 134098-61-6
Appearance Solid
Molecular Weight 421.49
Formel C₂₄H₂₇N₃O₄
Color White to off-white
SMILES

O=C(OC(C)(C)C)C1=CC=C(CO/N=C/C2=C(OC3=CC=CC=C3)N(C)N=C2C)C=C1
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (237.25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.3725 mL

11.8627 mL

23.7254 mL

5 mM

0.4745 mL

2.3725 mL

4.7451 mL

10 mM

0.2373 mL

1.1863 mL

2.3725 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 2.5 mg/mL (5.93 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 2.5 mg/mL (5.93 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (625 KB)
- English - EN (625 KB)
- Français - FR (625 KB)
- Deutsch - DE (625 KB)
- Norwegian - NO (625 KB)
- Español - ES (625 KB)
- Swedish - SV (625 KB)
- Italian - IT (625 KB)
- Korean - KR (625 KB)
- Portuguese - PT (625 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Motoba. K, et al. Species-specific detoxification metabolism of fenpyroximate, a potent acaricide.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.3725 mL	11.8627 mL	23.7254 mL	59.3134 mL
	5 mM	0.4745 mL	2.3725 mL	4.7451 mL	11.8627 mL
	10 mM	0.2373 mL	1.1863 mL	2.3725 mL	5.9313 mL
	15 mM	0.1582 mL	0.7908 mL	1.5817 mL	3.9542 mL
	20 mM	0.1186 mL	0.5931 mL	1.1863 mL	2.9657 mL
	25 mM	0.0949 mL	0.4745 mL	0.9490 mL	2.3725 mL
	30 mM	0.0791 mL	0.3954 mL	0.7908 mL	1.9771 mL
	40 mM	0.0593 mL	0.2966 mL	0.5931 mL	1.4828 mL
	50 mM	0.0475 mL	0.2373 mL	0.4745 mL	1.1863 mL
	60 mM	0.0395 mL	0.1977 mL	0.3954 mL	0.9886 mL
	80 mM	0.0297 mL	0.1483 mL	0.2966 mL	0.7414 mL
	100 mM	0.0237 mL	0.1186 mL	0.2373 mL	0.5931 mL

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(E)-Fenpyroximate

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